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Postgrad Doc - Caribbean ; 11(6): 268-77, Dec. 1995.
Artigo em Inglês | MedCarib | ID: med-5032


Skin manifestations are a common feature of HTLV-1 associated disorders and of HTLV-1 infection itself. These include the lymphomatous skin infiltrates in adult T-cell lymphoma/leukaemia, most commonly manifesting as persistent, generalised papules, nodules and plaques with later ulceration, acquired ichthyosis and xeroderma in HAM/TSP, infective dermatitis of children, dermatomyositis, crusted (Norwegian) scabies, psoriasiform rashes which may precede one of the more serious disease associations, and possibly also seborrhoeic dermatitis. Disorders typically associated with immunosuppression such as disseminated herpes zoster, and ulcerative non-healing herpes simplex may also be seen occasionally both in ATK as well as in other wise asymptomatic HTLV-1 infection (AU)

Humanos , Masculino , Feminino , Criança , Adulto , Vírus Linfotrópico T Tipo 1 Humano , Linfoma Cutâneo de Células T , Dermatite , Dermatomiosite , Escabiose , Psoríase , Herpes Zoster , Herpes Simples , Leucemia-Linfoma de Células T do Adulto , Paraparesia Espástica Tropical , Uveíte , Hipercalcemia , Anemia , Complexo Relacionado com a AIDS , Hanseníase , Sarcoidose , Dermatite Esfoliativa , Escleroderma Sistêmico , Dermatopatias Vesiculobolhosas , Eczema , Ictiose , Imunoglobulina G , Anticorpos Anti-HTLV-I , Staphylococcus , Streptococcus , Bronquiectasia , Catarata , Polimiosite , Eritema , Edema , Sarcoptes scabiei , Dermatite Seborreica , Tinha do Couro Cabeludo , Região do Caribe , Estados Unidos , Haiti , Japão , América do Sul , África
In. Levett, Paul N; Fraser, Henry S; Hoyos, Michael D. Medicine and therapeutics update 1990: proceedings of Continuing Medical Education symposia in Barbados, November 1988 & June 1989. St. Michael, University of the West Indies, (Cave Hill). Faculty of Medical Sciences, 1990. p.34-41.
Monografia em Inglês | MedCarib | ID: med-15007


This article looks at the history, development, progress and research of the Human Immunodeficiency Virus (HIV) which causes AIDS. The author reports of the ongoing research into a vaccine for HIV, he examines the viral life cycle and indicates the points at which the virus can be attacked, and classifies antiviral strategies

HIV , Infecções por HIV/classificação , Infecções por HIV/diagnóstico , Infecções por HIV/tratamento farmacológico , Infecções por HIV/epidemiologia , Infecções por HIV/história , Infecções por HIV/terapia , HIV-2/análise , HIV-2/classificação , HIV-2/crescimento & desenvolvimento , HIV-2/isolamento & purificação , HIV-2/patogenicidade , HIV-1/análise , HIV-1/classificação , HIV-1/crescimento & desenvolvimento , HIV-1/isolamento & purificação , HIV-1/patogenicidade , Sistema Imunitário/patologia , HIV , Complexo Relacionado com a AIDS/diagnóstico , Complexo Relacionado com a AIDS/tratamento farmacológico , Complexo Relacionado com a AIDS/etnologia , Complexo Relacionado com a AIDS/etiologia , Complexo Relacionado com a AIDS/história , Complexo Relacionado com a AIDS/terapia , Complexo Relacionado com a AIDS/transmissão , Vacinas/administração & dosagem , Vacinas/efeitos adversos , Vacinas/análise , Vacinas/classificação , Vacinas/diagnóstico , Vacinas/imunologia , Vacinas/farmacologia , Vacinas Virais/administração & dosagem , Vacinas Virais/efeitos adversos , Vacinas Virais/classificação , Vacinas Virais/diagnóstico , Vacinas Virais/farmacologia , Vacinas Virais/uso terapêutico , Soropositividade para HIV , Produtos do Gene tat/análise , Produtos do Gene tat/classificação , Produtos do Gene tat/diagnóstico , Produtos do Gene tat/uso terapêutico
Br J Obstet Gynaecol ; 96(2): 140-3, Feb. 1989.
Artigo em Inglês | MedCarib | ID: med-10006


In the 13 month period between June 1985 and July 1986, 27 children were found to be HIV positive in the Princess Margaret Hospital in Nassau. Nineteen of the children had clinical AIDS, four were in the prodromal phase and four were symptom free. The clinical course of these infants is presented. Of the 18 mothers 16 were screened and were all seropositive and asymptomatic. They remained healthy in spite of subsequent pregnancies in nine of them (56 percent during a follow-up period of between 13 and 65 months (mean 40 months). Fifteen of the 18 mothers were Haitian but only three had other risk factors, throwing doubt on the valur of selective screening in Afro-Caribbean countries. (AU)

Humanos , Recém-Nascido , Lactente , Pré-Escolar , Síndrome de Imunodeficiência Adquirida/congênito , Síndrome de Imunodeficiência Adquirida/epidemiologia , Complexo Relacionado com a AIDS/congênito , Complexo Relacionado com a AIDS/epidemiologia , Bahamas , Doenças em Gêmeos , Ensaio de Imunoadsorção Enzimática , Saúde da Família , Soropositividade para HIV/diagnóstico
West Indian med. j ; 37(suppl): 42, 1988.
Artigo em Inglês | MedCarib | ID: med-6590


From August 1985 through January 1986, 123 homosexual or bisexual men from the Kingston area were enrolled in a study to determine the prevalence of human immunodeficiency virus (HIV) and the human T-lymphotrophic virus type I (HLTV-I) and the levels of risk factors for these infections. Eighteen men (15 percent) were sero-positive for HIV and 11 (9 percent) were sero-positive for HTLV-I. Only one man was positive for both viruses. The median age was 27 years (range 17 to 70). Overall, the level of promiscuity was lower than that reported in studies of homosexual men in the U.S.A. and in Europe. However, almost a third of the men reported having had homosexual encounters with foreign visitors or whilst travelling outside Jamaica. The presence of lymphadenopathy (p<0.05) was higher in HIV sero-positive patients, as was the percentage who reported having sex with men from the U.S.A. (p=0.16). Men who were sero-positive for HTLV-I tended to be more promiscuous than their sero-negative counterparts; the proportion with a history of gonorrhoea and the mean number of homosexual acts per week were both increased (p<0.05). A history of receptive anal intercourse and the mean number of homosexual partners per month were increased in positive subjects but the difference did not reach statistical significance. These results suggest that HTLV-I is an endemic, sexually transmitted infection. In contrast, HIV appears to have entered this population through homosexual contact with foreigners; the lack of association between HIV infection and promiscuity may be due to the small number of positives and the sporadic nature of transmission early in an epidemic (AU)

Humanos , Masculino , Adulto , Infecções por HIV , Infecções por HTLV-I , Homossexualidade Masculina , Jamaica , Soropositividade para HIV , Complexo Relacionado com a AIDS , Gonorreia , Parceiros Sexuais