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Caribbean J Pharmacy ; 1(3): 32-7, Aug. 1986.
Artigo em Inglês | MedCarib | ID: med-8052


Asthma, chronic obstructive bronchitis, and emphysema represent different forms of chronic obstructive pulmonary disease (COPD). Because they have different causes and are based on different pathophysiology, it is reasonable to suspect they may respond differently to treatment. In particular, bronchodilators, such as theophylline, which are purported to act by preventing the spasm of bronchial smooth muscle, should work in asthma but not in chronic bronchitis or emphysema. However, theophylline and other bronchodilators do improve breathing in all three forms of COPD, although to different degrees. Theophylline's effectiveness in chronic bronchitis and emphysema is attributed, in part, to the observation that these forms of COPD commonly have a reversible component (bronchospastic). Furthermore, it is now known that theophylline's mechanism of action includes a strengthening of the diaphragm and other muscles of respiration. These additional mechanisms may explain theophylline's effectiveness in those forms of COPD that lack a bronchospastic component. (AU)

Humanos , Pneumopatias Obstrutivas/tratamento farmacológico , Teofilina/uso terapêutico , Asma , Bronquite , Enfisema
West Indian med. j ; 31(2): 82-5, June 1982.
Artigo em Inglês | MedCarib | ID: med-11390


We report the case of a 30-year-old diabetic woman who developed a urinary tract infection with the rare complications of emphysematous pyelitis and papillary necrosis. Both these complications are commoner in diabetics than in non-diabetics and emphysematous pyelitis is associated with a particularly poor prognosis, necessitating urgent surgery if antibiotic treatment fails. Papillary necrosis may cause obstruction acutely which may further magnify the problem. Long-term antibiotic therapy is recommended in view of the likelihood and danger of a recurrent urinary tract infection. (AU)

Adulto , Feminino , Humanos , Diabetes Mellitus/complicações , Enfisema/etiologia , Necrose Papilar Renal/etiologia , Pielite/etiologia , Infecções Urinárias/complicações , Jamaica
West Indian med. j ; 12(1): 34-8, Mar. 1963.
Artigo em Inglês | MedCarib | ID: med-10606


A study of the type and degree of emphysema has been carried out at the University Hospital of the West Indies using Gough-Wentworth whole lung sections. The lung tissue was obtained from a series of consecutive, unselected autopsies in 125 adults of both sexes, ages 17 years and over. The results show that both the incidence and severity of emphysematous change is greater in males than in females. The overall incidence of what is gauged to be clinically significant emphysema is similar to findings in temperate countries. Reservation must be taken in this comparison because the material was not compared with any from Europe or North America. It is possible that the disease is caused by factors different from those operating in temperate countries. Alternatively, the emphysema-producing processes in temperate and tropical countries are similar, but in temperate areas, clinical prominence results from secondary infection, which does not occur in Jamaica (AU)

Humanos , Adulto , Masculino , Feminino , Enfisema/epidemiologia , Enfisema/etiologia , Jamaica/epidemiologia , Pulmão/patologia
West Indian med. j ; 11(4): 284, Dec. 1962.
Artigo em Inglês | MedCarib | ID: med-7519


A study of 150 consecutive autopsies has been made to establish the extent of emphysema in Jamaica. This has been done by preparing large lung sections (Gough-Wentworth). From these it has been possible to classify and roughly grade the types of emphysema occurring in Jamaica and to correlate the changes with the sex and age of the patients. The results suggested that the incidence of the anatomical changes are similar to those found in temperate zones. This is surprising because, firstly causative factors such as cold, damp atmosphere and industrial pollution do not appear to operated in Jamaica, and secondly clinical lung disease does not play a very great part in the overall morbidity of the Jamaican community (AU)

Humanos , Enfisema/epidemiologia , Fatores Etários , Fatores Sexuais