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Toxicon ; 37(1): 159-165, January 1999. ilus
Artigo em Inglês | MedCarib | ID: med-17305


The clinicopathological features of four cases of scorpion envenoming by Tityus trinitatis are presented. The cardiac histopahtology is recorded in the two fatal cases. The pathology of the acute myocarditis was a mixed picture of a toxic myocarditis and coagulative myocytolysis. These cardiac lesions are also seen in catecholamine induced cardiotoxicity and lend support to the theory that an adrenergic surge follows scorpion envenoming. A brief review of scorpion envenoming syndrome is undertaken in the light of these findings (AU)

Humanos , Lactente , Criança , Venenos de Escorpião/efeitos adversos , Venenos de Escorpião/análise , Venenos de Escorpião , Trinidad e Tobago , Miocardite , Pancreatite/complicações , Pancreatite/diagnóstico , Edema Pulmonar/complicações , Edema Pulmonar/diagnóstico , Edema Pulmonar/patologia , Choque/diagnóstico
West Indian med. j ; 46(2): 38-42, June 1997.
Artigo em Inglês | MedCarib | ID: med-2063


This is the first report of dengue haemorrhagic fever and dengue shock syndrome in Trinidad. Dengue infection was confirmed serologically or by viral isolation in five patients, aged 15 to 33 years, who presented with fever, thrombocytopenia and haemoconcentration. Three patients developed dengue shock syndrome, which was fatal; although there was no haemorrhagic tendency among these patients, bleeding occurred shortly before death in one of them. Two patients who had dengue haemorrhagic fever survived. The co-circulation of dengue virus serotypes 1, 2 and 4 in the Caribbean facilitates the development of dengue shock syndrome (DSS) or dengue haemorrhagic fever (DHF). Clinicans should therefore be aware of their clinical features, laboratory diagnosis and clinical management. Appropriate public health interventions and improved surveillance should be implemented to reduce the risk of DHS/DSS associated mortality in Trinidad and Tobago.(AU)

Adolescente , Adulto , Relatos de Casos , Feminino , Humanos , Pessoa de Meia-Idade , Masculino , Choque/epidemiologia , Dengue/epidemiologia , Dengue/complicações , Febres Hemorrágicas Virais/epidemiologia , Febres Hemorrágicas Virais/complicações , Surtos de Doenças , Evolução Fatal , Trinidad e Tobago/epidemiologia , Vírus da Dengue/isolamento & purificação
West Indian med. j ; 26(2): 59-65, June 1977.
Artigo em Inglês | MedCarib | ID: med-11215


Following the administration of levallorphan(100 mg/kg) rats' well-established avoidance behaviour is severly depressed for 30 minutes. During this period, animals are almost incessantly shocked. During saline trials, rats receive relatively few shocks. It is postulated that the rate enhancement observed after the drug-induced depressant period is probably due to the excessive stress which animals undergo during the depressive phase. Following drug treatment, rats were kept out of operant during the depressive phase. No rate enhancement was observed throughout the 120-minute experimental period. Response rate enhancement seems to depend on the level of stress during the depressant phase of the drug (AU)

21003 , Feminino , Humanos , Ratos , Levalorfano/farmacologia , Aprendizagem da Esquiva/efeitos dos fármacos , Depressão Química , Levalorfano/administração & dosagem , Choque , Estresse Psicológico , Fatores de Tempo
West Indian med. j ; 8(1): 50-6, Mar. 1959.
Artigo em Inglês | MedCarib | ID: med-12794


A brief review of the patho-physiology of burns is presented. The main cause of shock following body burns is loss of circulating blood volume either to the exterior or into the burn area. This is best remedied by prompt replacement in accordance with the recommendations of Evans as far as volume and composition are concerned. The hourly urinary output and clinical response of the patient should be the milestones of therapy. Special care must be exercised in the management of the following categories:- children with more than 10 percent body burns, all patients with more than 50 percent involvement, patients over 50 years of age, those with pre-existing cardiovascular, respiratory or renal disease, and those with respiratory burns. Significant nitrogen depletion and anaemia follow most major burns and these must be anticipated or corrected promptly if delayed convalescence and retarded wound healing are to be avoided. (AU)

Humanos , Criança , Adulto , Queimaduras/terapia , Equilíbrio Hidroeletrolítico , Queimaduras/fisiopatologia , Choque/terapia