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1.
Clin Chim Acta ; 30(1): 17-23, Oct. 1970.
Artigo em Inglês | MedCarib | ID: med-14760

RESUMO

Beta-aminopropionaldehyde is one of the serum aldehydes whose level increases on treating serum with As2O3 and methanol. In animal tissues, beta-aminopropionaldehyde can arise directly from the oxidation of spermidine or diaminopropane. A pathway linking spermidine, b-aminopropionaldehyde and malondialdehyde to the control of RNA and DNA synthesis is proposed (AU)


Assuntos
Humanos , 21003 , Aldeídos/sangue , Metanol/farmacologia , Aldeídos/metabolismo , Oxirredutases atuantes sobre Doadores de Grupo CH-NH/metabolismo , Aminas/sangue , Arsenicais/farmacologia , Derivados de Benzeno , Divisão Celular/efeitos dos fármacos , Química , Cromatografia em Camada Delgada , Dinitrofenóis , DNA/biossíntese , Hidrazinas , Rim/enzimologia , Malonatos/análise , Propionatos/sangue , RNA/biossíntese , Espermina/metabolismo , Suínos
2.
Clin Chim Acta ; 30(1): 13-6, Oct. 1970.
Artigo em Inglês | MedCarib | ID: med-14761

RESUMO

On heating human serum with As2O3 in the presence of methanol, the level of aldehyde is increased. The increase, expressed as a percentage of the total aldehyde content, is referred to as the bound aldehyde. In the sera of patients with early malignancy, the value of bound aldehyde is found to be significantly lower than that of normal sera, but as metastases occur, it rises above the normal value. In the sera of patients with malignancy, but who responded to treatment, the value for bound aldehyde is similar to that found in the sera of patients with non-malignant disease (AU)


Assuntos
Humanos , Aldeídos/sangue , Arsenicais/farmacologia , Métodos , Neoplasias/sangue , Ligação Proteica
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