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West Indian med. j ; 41(suppl 1): 52, Apr. 1992.
Artigo em Inglês | MedCarib | ID: med-6551


Forty-eight paediatric patients admitted with bacterial meningitis during a 10-year period, comprising 22 males (46 percent) and 26 females (54 percent), were reviewed. Ages ranged between 7 weeks and 12 years (mean 2.7 years). The mean 10-year incidence was 29/10,000 ward admissions, with a peak incidence of 69/10,000 admissions in 1989. The highest seasonal prevalence occurred during the dry months. Twenty-five patients (52 percent) were less than 2 years of age. Predominant symptoms were fever (85 percent), gastrointestinal (65 percent), and lethargy (40 percent). Frequently associated illnesses included upper respiratory infections in 21 (44 percent), and otitis media in 5(10 percent) of cases. H. influenzae was cultured from the cerebrospinal fluid in 34 cases (71 percent), S. pneumoniae in 4 cases (8 percent), and no organism in 10 cases (21 percent). Thirteen patients (27 percent) had received antibiotic therapy within a week of admission. Initial therapy consisted of parenteral ampicillin and chloramphenicol in 37 cases (77 percent), penicillin and chloramphenicol in 9 cases (19 percent) chlodramphenicol in 1 (2 percent), and trimethoprin/sulfamethoxazole in 1 case (2 percent). These data support a case for routine administration of H. influenzae B vaccine which will lead to the eradication of, or reduction of the overall incidence of bacterial meningitis in childhood (AU)

Lactente , Pré-Escolar , Criança , Meningite/epidemiologia , Infecções Bacterianas/epidemiologia , Criança , Barbados/epidemiologia , Febre , Gastroenteropatias , Fases do Sono , Infecções Respiratórias , Otite Média , Streptococcus pneumoniae/imunologia , Ampicilina/uso terapêutico , Cloranfenicol/uso terapêutico , Penicilinas/uso terapêutico , Trimetoprima/uso terapêutico , Sulfametoxazol/uso terapêutico , Haemophilus influenzae/imunologia
West Indian med. j ; 41(1): 41-2, Mar. 1992.
Artigo em Inglês | MedCarib | ID: med-11735


Persistant symptomatic hypoglycaemia developed in a 26-year-old woman with chronic renal failure. Several factors, including the use of sulfametethroxaole, recent peritoneal dialysis, and poor nutrition may have combined with defective glycogenosis and gluconeogenesis present in chronic renal failure to play a role in its aetiology. Increased awareness of this condition is necessary because chronic renal failure is common in the Caribbean. (AU)

Humanos , Adulto , Feminino , Hipoglicemia/etiologia , Insuficiência Renal Crônica/complicações , Glucose/uso terapêutico , Uremia/complicações , Hipoglicemia/terapia , Diálise Peritoneal/efeitos adversos , Sulfametoxazol/efeitos adversos , Transtornos Nutricionais/complicações , Doença de Depósito de Glicogênio/complicações
West Indian med. j ; 37(4): 201-4, Dec. 1988.
Artigo em Inglês | MedCarib | ID: med-11665


The in-vitro sensitivity to ampicillin, cotrimoxazole, nitrofuratoin, nalidixic acid and mecillinam was determined for 511 organisms isolated from 399 consecutive urine specimens. Urine specimens were divided into those of hospital in-patient origin (group B). Group B organisms were more sensitive than group A organisms. Over 75 percent of all group B organisms were sensitive to nitrofurantoin, nalidixic acid and mecillinam. Organisms resistant to multiple antibiotics were more frequently isolated from group A catheterized patients and are now less frequently isolated than in 1983. The antibiotic implications of these findings are discussed (AU)

Humanos , Andinocilina Pivoxil/uso terapêutico , Antibacterianos/uso terapêutico , Testes de Sensibilidade Microbiana , Infecções Urinárias/microbiologia , Andinocilina/uso terapêutico , Administração Oral , Amoxicilina/uso terapêutico , Ampicilina/uso terapêutico , Combinação de Medicamentos/uso terapêutico , Ácido Nalidíxico/uso terapêutico , Nitrofurantoína/uso terapêutico , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêutico , Infecções Urinárias/tratamento farmacológico , Estudos Prospectivos