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2.
Arch Dis Child ; 48(11): 901-5, Nov. 1973.
Artigo em Inglês | MedCarib | ID: med-13322

RESUMO

The mean summed skinfold at 6 sites in 20 malnourished Jamaican children was 24.5mm on admission to hospital and 49.8mm on discharge. Marasmic children initially had thinner skinfolds than children with oedematous malnutrition, and they had a highly significant reduction in total specific thermal insulation. During their first week in hospital there was a significant positive correlation between nocturnal mean rectal temperature in the malnourished children and their skinfold thickness and specific thermal insulation. Similar correlations for daytime rectal temperature were not statistically significant. We conclude that loss of thermal insulation may be of importance in the genesis of hypothermia in the sleeping malnourished child, whose posture and inactivity favour a negative heat balance. (AU)


Assuntos
Humanos , Lactente , Pré-Escolar , Masculino , Feminino , Regulação da Temperatura Corporal , Transtornos Nutricionais/fisiopatologia , Pregas Cutâneas , Temperatura Corporal , Edema/fisiopatologia , Meio Ambiente , Jamaica , Kwashiorkor/fisiopatologia , Desnutrição Proteico-Calórica/fisiopatologia , Metabolismo
3.
J Physiol ; 233(Aug): 75-91, 1973.
Artigo em Inglês | MedCarib | ID: med-10772

RESUMO

Twelve malnourished Jamaican children, aged 4-6 months, were studied before and after treatment, to see whether malnutrition impared their response to cold. When they were studied in the post-absorptive state and in a neutral thermal environment, they had a lower rate of oxygen consumption per kg body weight, a slower pulse rate, lower body temperatures, lower R.Q., and evidence of a smaller peripheral blood flow on admission to hospital than they did after recovery. The malnourished children failed to increase their heat production above resting levels at 25§ C, and their rectal temperature fell at a rate of 1§ C/hr in spite of a further decrease in peripheral circulation. When they had recovered they maintained their body temperature within the normal range on exposure to this temperature, while increasing their heat production by 20 percent. The thermogenesis was apparently of the non-shivering type. There was evidence of increased metabolic activity in the interscapular brown fat pad at 25§ C both on admission and before discharge. In the malnourished children this activity was not sufficient to produce a measurable increase in total oxygen consumption. Interscapular brown fat was examined at autopsy in thirteen malnourished and fifteen well nourished children aged 1-24 months. Lipid depletion was found in this tissue in the former but not in the latter. This may explain the impared response of the malnourished child to cold. (AU)


Assuntos
Humanos , Lactente , Masculino , Feminino , Regulação da Temperatura Corporal , Temperatura Baixa , Transtornos da Nutrição do Lactente/fisiopatologia , Autopsia , Velocidade do Fluxo Sanguíneo , Tecido Adiposo Marrom/metabolismo , Lipídeos/metabolismo , Consumo de Oxigênio , Pulso Arterial , Respiração , Temperatura Cutânea
4.
West Indian med. j;21(4): 253-6, Dec. 1972.
em Inglês | MedCarib | ID: med-11014

RESUMO

A child with kernicterus and severe marasmus had marked thermoregulatory instability. An initial episode of hypothermia was attributed to deficient energy reserves, while experimental evidence suggested that subsequent intermittent fever was due to an unstable set-point of the hypothalmic thermoistat. Impaired vasomotor reactivity as a result of autonomic dysfunction may also have contributed to the unstable body temperature (AU)


Assuntos
Humanos , Lactente , Masculino , Kernicterus/fisiopatologia , Regulação da Temperatura Corporal , Desnutrição Proteico-Calórica/fisiopatologia , Hipoglicemia , Hipotermia
5.
West Indian med. j ; 21(3): 164, Sept. 1972.
Artigo em Inglês | MedCarib | ID: med-6263

RESUMO

Twelve malnourished babies were exposed, in sleep, to an environmental temperature of 24§C for 30 minutes. Their oxygen consumption decreased by 13.5 percent and their mean rectal temperature fell from 37.05§C to 35.95§C. When these children, after recovery, were exposed to the same environmental stress, their oxygen consumption increased by 19 percent and their rectal temperature fell from 37.36§C to 36.65§C. These findings provide more evidence that thermoregulation is impaired in malnourished children, and may help to explain the occurrence of hyperthermia in some of them (AU)


Assuntos
Humanos , Lactente , Regulação da Temperatura Corporal , Transtornos Nutricionais , Jamaica
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