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Sturge-Weber syndrome is a rare, sporadic, progressive neurocutaneous condition that presents with congenital hamartomatous malformations, epilepsy, and a variety of facial symptoms. We discussed a rare case of an eighteen-year-old female child who came to our neurology department with status epilepticus, mental impairment, and a port-wine in the lateral left side of her face. We diagnosed Sturge-Weber syndrome after a thorough neurological and radiological evaluation. The purpose of presenting this case is to illustrate both the characteristic presentation and the complications associated with managing Sturge-Weber syndrome.
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Introduction: Nasopalatine duct cyst (NDC) is the most prevalent non-odontogenic cyst emerging from the epithelial remnants in the maxillary incisive canal. A sublabial or transpalatal approach is performed to enucleate NDC completely. More recently, transnasal endoscopic marsupialization has been used gradually. Case Presentation: A 24-year-old male patient with a large nasopalatine duct cyst with a diameter of 51 mm was managed by transnasal endoscopic marsupialization under general anesthesia. The presentation involves painless swelling around the left side of the anterior maxilla and bulging of the hard palate. No postoperative complications were observed after a 3-month follow-up. Transnasal endoscopic marsupialization is a minimally invasive surgery for large NDC. Clinical discussion: Approximately 1% of the population has a nasopalatine duct cyst. Surgical treatment was carried out under general anesthesia; the cyst was dissected and removed using a typically transnasal endoscopic marsupialization technique. Conclusion: The cause of the NDC is unclear. Simple surgical resection and clinical and radiological control are recommended to ensure the case is resolved correctly.
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Introduction and importance: Paecilomyces species are rare fungi that are resistant to standard treatment and have increasing clinical relevance. The Purpureocillium lilacinum, formerly known as Paecilomyces lilacinus, has a unique sensitivity for the corneal surface. However, only a few cases have been documented globally. This case report presents the successful management of a patient with Paecilomyces lilacinus keratitis with topical voriconazole and oral itraconazole. Case presentation: A 40-year-old woman came to our ophthalmology clinic complaining of right eye pain due to a severe corneal infection in her right eye. Corneal scraping and identification of the cultured pathogen were performed, which revealed Paecilomyces lilacinus. The corneal infection improved after being treated with hourly topical voriconazole (10 mg/ml) and oral traconozole. Clinical discussion: Paecilomyces/Purpureocillium keratitis, which accounts for 5% of keratomycosis cases in tropical and subtropical areas, is extremely rare. It does not respond well to conventional antifungal treatment and frequently requires therapeutic surgery. Risk factors include wearing contact lenses, ocular trauma, ocular surgery, corticosteroids, and intraocular lens implantation. Conclusion: For the treatment of Paecilomyces lilacinus keratitis that is unresponsive to conventional antifungal medications, voriconazole may be helpful. Early organism detection and the appropriate therapy are necessary for the management of keratitis.
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BACKGROUND: Dengue has become an alarming global problem and is endemic in many countries, particularly in tropical and subtropical countries. The aim of this study was to investigate dengue fever outbreak in Banadir Region, Somalia, to understand the risk factors (time, place, personal characteristics). METHODS: A descriptive cross-sectional study was undertaken to determine the levels of circulating anti-dengue virus antibodies and DENV NS1 antigen among Banadir Region residents, while a questionnaire survey was conducted to understand the clinical and demographic characteristics of the patients. RESULTS: A total of 735 febrile patients were studied, with 55.6% men and 44.3% women. The majority of the participants were children aged 14 years and younger. Among them, 10.8% tested positive for IgM antibodies against dengue virus (DENV), while the prevalence of DENV NS1 antigen was 11.8%. Fever and myalgia were the most common symptoms observed in the DENV-positive patients. CONCLUSIONS: A dengue fever outbreak has been confirmed in Banadir region, Somalia. This study provides information on the most affected districts and identifies risk factors contributing to DF outbreaks. The study recommends improving outbreak readiness and response, particularly in surveillance and laboratory diagnostics, by fostering intersectoral collaboration and establishing regulatory frameworks for financial and operational participation.
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Virus del Dengue , Dengue , Niño , Masculino , Humanos , Femenino , Dengue/epidemiología , Estudios Transversales , Somalia/epidemiología , Ensayo de Inmunoadsorción Enzimática , Factores Socioeconómicos , Brotes de Enfermedades , Fiebre/epidemiología , Anticuerpos AntiviralesRESUMEN
Introduction and Importance: Ecthyma gangrenosum is a skin lesion that can be caused by either bacterial hematogenous seeding or a primary skin infection. Despite being the most frequent causal agent, Pseudomonas aeruginosa is not the only bacteria that has been involved. Other types of bacteria may also be implicated in the etiology of EG: cocci bacteria, both gram-positive and gram-negative. Case Presentation: Here, we report the case of a 10-month-old male infant who developed ecthyma gangrenosum after a measles infection. At the time of admission, the patient had a high fever of about 40.3°C and appeared conscious. Physical examination revealed several skin lesions that were in various stages of development and appeared as nodules with a central crust and round, ulcerated, necrotic papules in the face, chest, and upper extremities. Laboratory tests showed CRP of 25 mg/l, LDH of 579 U/L, WBC of 15.06 × 1000/mm3, and absolute neutrophils of 1930/mm3 (12.8%). The result of the culture showed coagulase-negative Staphylococcus. According to the drug susceptibility test results, intravenous Vancomycin (20 mg/kg per dose, 3 times daily) should be started. A coagulase-negative Staphylococcus was eliminated as a result of this defervescence. The necrotic lesion was surgically removed from the patient. Clinical Discussion: Ecthyma gangrenosum is the all-over-the-body cutaneous manifestation of pseudomonas infection in sepsis patients. Patients who suffer from severe illnesses. Immune deficiencies commonly increase the chance of acquiring EG. Our patient had a history of measles, which led to neutropenia before developing EG. The management of ecthyma gangrenosum requires early identification and antimicrobial treatment. Conclusion: We describe a measles patient who developed coagulase-negative Staphylococcus ecthyma gangrenosum and had good results from both surgical debridement and systemic antibiotics. Our case serves as an example of the uncommon presentation of ecthyma gangrenosum. This example emphasizes the value of an early diagnosis and vigorous antimicrobial therapy in cases where ecthyma gangrenosum is clinically suspected.
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Tetanus is still a major problem in sub-Saharan African countries. This study aims to evaluate tetanus disease and vaccine awareness among healthcare workers in Mogadishu. This descriptive, cross-sectional study was scheduled for January 2-7, 2022. A questionnaire consisting of 28 questions was applied in a face-to-face manner to 418 healthcare workers. Only health workers aged≥18 living in Mogadishu were included. Questions about sociodemographic characteristics, tetanus disease, and vaccines were developed. 71.1% of the participants were female, 72% were Ë25 years old, 42.6% were nursing students, and 63.2% had a university education. It was observed that 46.9% of the volunteers had an income level of <$250, and 60.8% resided in the city center. 50.5% of the participants received a tetanus vaccine in their childhood. Questions to determine participants' level of knowledge about tetanus and the tetanus vaccine were responded to with an accuracy of between 44 and 77%. Although 38.5% of the participants reported that they were exposed to trauma at least once a day, the rate of those who had three or more doses of the vaccine was only 10.8%. On the other hand, 51.4% reported that they had received training about tetanus and vaccination. There was a significant difference (p < .001) in terms of knowledge level among sociodemographic characteristics. The fear of side effects was the most important reason for not being vaccinated. Healthcare workers in Mogadishu have little awareness of tetanus disease and vaccines. Efforts to improve education and other factors will be sufficient to eliminate the disadvantage brought about by the socio-demographic structure.
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Tétanos , Humanos , Femenino , Niño , Adulto , Masculino , Tétanos/prevención & control , Estudios Transversales , Somalia , Vacunación , Toxoide Tetánico , Personal de SaludRESUMEN
Restoration of degraded drylands is urgently needed to mitigate climate change, reverse desertification and secure livelihoods for the two billion people who live in these areas. Bold global targets have been set for dryland restoration to restore millions of hectares of degraded land. These targets have been questioned as overly ambitious, but without a global evaluation of successes and failures it is impossible to gauge feasibility. Here we examine restoration seeding outcomes across 174 sites on six continents, encompassing 594,065 observations of 671 plant species. Our findings suggest reasons for optimism. Seeding had a positive impact on species presence: in almost a third of all treatments, 100% of species seeded were growing at first monitoring. However, dryland restoration is risky: 17% of projects failed, with no establishment of any seeded species, and consistent declines were found in seeded species as projects matured. Across projects, higher seeding rates and larger seed sizes resulted in a greater probability of recruitment, with further influences on species success including site aridity, taxonomic identity and species life form. Our findings suggest that investigations examining these predictive factors will yield more effective and informed restoration decision-making.
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Ecosistema , Plantones , Cambio Climático , Humanos , Plantas , SemillasAsunto(s)
Infecciones por Coronavirus/terapia , Pandemias , Neumonía Viral/terapia , Universidades , Betacoronavirus , COVID-19 , Infecciones por Coronavirus/prevención & control , Infecciones por Coronavirus/psicología , Educación en Salud , Humanos , Nigeria/epidemiología , Pandemias/prevención & control , Neumonía Viral/prevención & control , Neumonía Viral/psicología , SARS-CoV-2RESUMEN
Gender and educational equality have been extensively debated by scholars in South Africa, researchers have failed to capitalize on why enthusiastic postgraduate female students have a higher dropout rate than their male counterparts. This study has capitalized on this vacuity, via a phenomenological lens, to examine the challenges experienced by female postgraduate students at University of KwaZulu-Natal. This study presents the lived experiences of ten female postgraduate honours students from University of KwaZulu-Natal in 2017. The study sought to research the learner's impetus to pursue postgraduate studies and the limitations eminent during the process. The ostensive constraints acknowledged by participants have seeped in socio-cultural beliefs rooted in traditional and religious affirmations, financial impediments and balancing their educational pursuit with traditional role expectations within their gendered familial domain. This study advances the requirement to critique the socio-cultural principles that impede females' succession in postgraduate studies while simultaneously engaging in discourse on the concealed practices in higher educational institutions separating students based on gender.
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A comparative study of testicular biometry was done in rams using three major breeds of sheep in Nigeria. Biometrical parameters observed were scrotal circumference (SC), testes weight (TW), testes length (TL), tunica albuginea weight (TAW), testes volume (TV), testes density (TD), epididymal weight (EW), epididymal length (EL), caput (CA), corpus (CO), cauda weight (CU), epididymal volume (EV) and epididymal density (ED). The results showed significant differences (p<0.05) between the Uda, Balami and Yankasa breed in the SC, TW, TV, EW, EL, CA, CO, CU, and EV. The Uda had significantly higher (p<0.05) values in most of the parameters examined than the two other breeds. A bilateral symmetry was observed for Uda and Balami in testes weight and testes volume. It was concluded that the testicular biometry of Uda and Balami observed are suggestive of high spermatozoa per unit mass of the testes and epididymis and subsequently higher fertility, and these biometry can be used by farmers in selecting good breeding animals for genetic improvement.
Se realizó un estudio comparativo de la biometría testicular en carneros con las tres razas principales de ovejas de Nigeria. Los parámetros biométricos observados fueron la circunferencia escrotal (CE), peso testicular (PT), longitud testicular (LT), peso de la túnica albugínea (PTA), volumen testicular (VT), densidad testicular (DT), peso del epidídimo (PE), longitud del epidídimo (EL), peso de la cabeza (CA), cuerpo (CU) y cauda (CA), volumen del epidídimo (VE) y densidad del epidídimo (ED). Los resultados mostraron diferencias significativas (p <0,05) entre la raza Uda, Balami y Yankasa para la CE, PT, VT, PE, LE, CA, CU, CA, y VE. La raza Uda tuvo valores significativamente mayores (p <0,05) en la mayoría de los parámetros analizados con las otras dos razas. Se observó una simetría bilateral en el peso de los testículos y el volumen de los testículos para las razas Uda y Balami. Se concluyó que la biometría testicular observada en las razas Uda y Balami son sugerentes de alta cantidad de espermatozoides por unidad de masa de los testículos y el epidídimo, y subsecuentemente una alta fertilidad. La biometría de éstos pueden ser utilizada por los agricultores en la selección de buenos animales para la mejora genética de las crías.
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Animales , Masculino , Ovinos/anatomía & histología , Genitales Masculinos/anatomía & histología , Escroto/anatomía & histología , Testículo/anatomía & histología , Epidídimo/anatomía & histologíaRESUMEN
PURPOSE: In the standard classical method of indirect inguinal hernia (IIH) repair in female children, after transligation of hernia sac along with round ligament at the level of internal ring, the distal portion is divided or cut off, thereby removing a possible future support for the internal genital organs. In this article, we propose a modification to the standard technique for IIH repair which preserves the continuity of round ligament along with hernia sac without increasing the recurrence rate. METHODS: In a 3-year prospective clinical trial, from March 2007 to March 2010, IIH repairs were performed on 217 female children. In all of these cases, the hernia sac along with round ligament is only transligated at the level of internal ring and a window is created in the distal portion of the sac to prevent a hydrocele formation and the continuity of round ligament along with hernia sac was preserved. The charts of these patients were then analyzed to determine if recurrence had occurred. In addition, we noted any other early postoperative complications such as wound infection, bleeding, and tolerance. RESULTS: Within the 25-month mean follow-up period (6-36 months), none of the patients developed any of the above-mentioned complications. The most important result of this study was that preserving the continuity of round ligament along with hernia sac did not increase the rate of recurrence. CONCLUSION: On the basis of results obtained from this study, we conclude that preserving the continuity of round ligament along with hernia sac in female children during IIH repair does not increase the rate of recurrence, and is less intrusive to the normal anatomy of the inguinal region and needs less time to do.
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Hernia Inguinal/cirugía , Herniorrafia/métodos , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Estudios Prospectivos , Recurrencia , Ligamento Redondo del ÚteroRESUMEN
Prior to the introduction of cosmopolitan medicine, traditional medicine used to be the dominant medical system available to millions of people in Africa in both rural and urban communities. However, the arrival of the Europeans marked a significant turning point in the history of this age-long tradition and culture. This paper examines the trends and challenges of traditional medicine in Africa. The impact of colonialism on African traditional medicine is also examined. Although the paper is on Africa, references are drawn around the world to buttress the growing demand for traditional medicine. The paper concludes that to minimise the current distrust between modern and traditional doctors and to achieve the objective of regulation, standardisation and cooperation, both traditional and modern doctors must acknowledge their areas of strengths and weaknesses from which they operate and be genuinely concerned about the difficult but necessary task of being human.