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1.
Prog Orthod ; 25(1): 16, 2024 May 06.
Article En | MEDLINE | ID: mdl-38705914

OBJECTIVE: This study aimed to investigate orthodontists' utilization and perceptions of tele-orthodontics. MATERIALS AND METHODS: A 30-item online survey was distributed to members of the American Association of Orthodontists (AAO). The questionnaire encompassed topics concerning the orthodontists' utilization, perceptions, clinical applications, limitations, and concerns regarding tele-orthodontics. Descriptive statistics were employed, and comparisons between responses from users and non-users were conducted  using Wilcoxon rank-sum tests and Fisher's exact tests. RESULTS: 152 members completed the survey, (response rate: 2.4%). More than two third of respondents (69.74%) were users of tele-orthodontics. Users were more aligned with the belief that tele-orthodontics facilitates effective communication (mean ± standard deviation (SD) 4.06 ± 0.83 vs. 3.33 ± 0.94, p < 0.001). Both groups agreed on the requirement of patient fees for tele-orthodontic visits (mean ± SD: 3.62 ± 1.11 users vs. 3.74 ± 1.02 non-users, p = 0.659), and on the capability  of the system to reduce unwarranted referrals (p = 0.20). The majority of participants acknowledged  the utility of the system in monitoring aligners' patients (89% in users vs. 61% in non-users, p < 0.001). Non-users expressed greater concerns regarding privacy risks (mean ± SD: 3.06 ± 0.97 users vs. 3.57 ± 0.86 non-users, p = 0.002). Both groups stressed the significance of obtaining informed consent before utilizing tele-orthodontics. CONCLUSIONS: The widespread acceptance of tele-orthodontics among AAO members was apparent, as demonstrated by their recognition of its effectiveness. There was notable variation in how users and non-users perceived tele-orthodontics. The study's results offer valuable insights into both the potential benefits and drawbacks of incorporating this technology into clinical practice from the clincians' perspective.


Attitude of Health Personnel , Orthodontics , Orthodontists , Telemedicine , Humans , United States , Surveys and Questionnaires , Orthodontists/psychology , Female , Societies, Dental , Male , Adult
2.
J World Fed Orthod ; 2024 Apr 19.
Article En | MEDLINE | ID: mdl-38643033

BACKGROUND: An uncommon location for placing miniscrews, used to provide anchorage control in various tooth movements, is the alveolar ridge. This study aimed to provide an evaluation of the success rate of alveolar ridge miniscrews and examine variables that might impact their success. METHODS: Charts for 295 patients who had miniscrews were screened. Twenty patients (5 male and 15 female: average age = 38.15 ± 15.10 years) with a total of 50 alveolar ridge miniscrews were analyzed. A customized data form was used to collect patients' and miniscrews' related variables. Kaplan-Meier estimator was used for the survival function, whereas Cox proportional hazards regression models were used to associate collected variables with alveolar ridge miniscrew survival. RESULTS: In total, 31 (62.0%) miniscrews were stable and 19 (38.0%) failed. The survival time for those that failed was 6.03 ± 7.08 months. The follow-up period for those that survived was 35.84 ± 19.47 months. Male gender versus female (hazard ratio [HR] 2.46; 95% confidence interval [CI] 1.35-4.48; P = 0.003), and if the miniscrew was a replacement versus non-replacement (HR 0.27; 95% CI 0.07-0.99; P = 0.048) influenced the survival. Additionally, miniscrews that were used for both indirect and direct or indirect anchorage alone plus those with evidence of splinting showed a 100% survival rate, which led to an HR 0 (P < 0.001). When the previously mentioned variables were modeled, none seemed to have a significant effect on failure except for splinting and type of anchorage (P < 0.001), because none of the splinted miniscrews failed. CONCLUSIONS: The failure rate of alveolar ridge miniscrews was (38.0%) over 6.03 ± 7.08 months. The survival rate was (62.0%) over 35.84 ± 19.47 months. The evidence of splinting and the type of anchorage had a significant effect on survival probability.

3.
Orthod Craniofac Res ; 2024 Apr 18.
Article En | MEDLINE | ID: mdl-38634214

INTRODUCTION: This study aimed to compare the efficiency of temporary anchorage devices (TADs) and fixed functional appliances (FFAs) for mandibular molar protraction. METHODS: Orthodontic records of 1050 consecutively treated patients with molar protraction were screened. Thirty-six records (22 females and 14 males; mean age, 17.4 years) were divided into two groups: TAD (21 subjects with 25 edentulous spaces) and FFA (15 subjects with 24 edentulous spaces). The primary outcome measure was the efficiency of protraction [magnitude and time required for protraction (rate) and anchor loss (AL)]. The secondary outcomes involved measuring the type of tooth movement (TOTM), external apical root resorption (EARR), alveolar bone height change (ABHC), alveolar bone width change (ABWC) and appliance failure. RESULTS: The rate of tooth movement was significantly higher for FFAs (0.83 ± 0.35 mm/month) versus TADs (0.49 ± 0.2 mm/month) (P = .005). Total treatment duration was less for FFAs (34.78 ± 8.1 months) versus TADs (47.72 ± 13.94 months) (P = .002). TOTM was similar for both (P = .909). EARR was 1.42 ± 1.38 mm for TAD and 1.25 ± 0.88 mm for FFA (P = .81). ABHC increased in the FFA group (1.01 ± 3.62 mm) and decreased for the TAD group (0.68 ± 1.66 mm). ABWC increased for both TAD (1.81 ± 1.73 mm) and FFA (1.75 ± 1.35 mm). The failure rate was 50% for FFAs and 33% for TADs. CONCLUSIONS: Both systems provided translation of lower molars with comparable anchorage control. However, FFAs were more efficient than TADs for lower molar protraction.

6.
Angle Orthod ; 94(3): 263-272, 2024 May 01.
Article En | MEDLINE | ID: mdl-38195060

OBJECTIVES: To assess the accuracy of ChatGPT answers concerning orthodontic clear aligners. MATERIALS AND METHODS: A cross-sectional content analysis of ChatGPT generated responses to queries related to clear aligner treatment (CAT) was undertaken. A total of 111 questions were generated by three orthodontists based on a set of predefined domains and subdomains. The artificial intelligence (AI)-generated (ChatGPT) answers were extracted and their accuracy was determined independently by five orthodontists. The accuracy of answers was assessed using a prepiloted four-point scale scoring rubric. Descriptive statistics were performed. RESULTS: The total mean accuracy score for the entire set was 2.6 ± 1.1. It was noted that 58% of the AI-generated answers were scored as objectively true, 18% were selected facts, 9% were minimal facts, and 15% were false. False claims included the ability of CAT to reduce the need for orthognathic surgery (4.0 ± 0.0), improve airway function (3.8 ± 0.5), achieve root parallelism (3.6 ± 0.5), alleviate sleep apnea (3.8 ± 0.5), and produce more stable results compared to fixed appliances (3.8 ± 0.5). CONCLUSIONS: The overall level of accuracy of ChatGPT responses to questions concerning CAT was suboptimal and lacked citations to relevant literature. Ability of the software to offer current and precise information was limited. Therefore, clinicians and patients must be mindful of false claims and relevant facts omitted in the answers generated by ChatGPT.


Artificial Intelligence , Orthodontic Appliances, Removable , Humans , Cross-Sectional Studies , Software , Orthodontic Appliances, Fixed
7.
J Dent ; 142: 104840, 2024 03.
Article En | MEDLINE | ID: mdl-38219888

OBJECTIVES: To assess whether ChatGPT can help to identify predatory biomedical and dental journals, analyze the content of its responses and compare the frequency of positive and negative indicators provided by ChatGPT concerning predatory and legitimate journals. METHODS: Four-hundred predatory and legitimate biomedical and dental journals were selected from four sources: Beall's list, unsolicited emails, the Web of Science (WOS) journal list and the Directory of Open Access Journals (DOAJ). ChatGPT was asked to determine journal legitimacy. Journals were classified into legitimate or predatory. Pearson's Chi-squared test and logistic regression were conducted. Two machine learning algorithms determined the most influential criteria on the correct classification of journals. RESULTS: The data were categorized under 10 criteria with the most frequently coded criteria being the transparency of processes and policies. ChatGPT correctly classified predatory and legitimate journals in 92.5 % and 71 % of the sample, respectively. The accuracy of ChatGPT responses was 0.82. ChatGPT also demonstrated a high level of sensitivity (0.93). Additionally, the model exhibited a specificity of 0.71, accurately identifying true negatives. A highly significant association between ChatGPT verdicts and the classification based on known sources was observed (P <0.001). ChatGPT was 30.2 times more likely to correctly classify a predatory journal (95 % confidence interval: 16.9-57.43, p-value: <0.001). CONCLUSIONS: ChatGPT can accurately distinguish predatory and legitimate journals with a high level of accuracy. While some false positive (29 %) and false negative (7.5 %) results were observed, it may be reasonable to harness ChatGPT to assist with the identification of predatory journals. CLINICAL SIGNIFICANCE STATEMENT: ChatGPT may effectively distinguish between predatory and legitimate journals, with accuracy rates of 92.5 % and 71 %, respectively. The potential utility of large-scale language models in exposing predatory publications is worthy of further consideration.


Periodicals as Topic , Cross-Sectional Studies
8.
Prog Orthod ; 24(1): 37, 2023 Nov 13.
Article En | MEDLINE | ID: mdl-37953383

AIMS: To systematically assess the efficacy of the various interventions used to intrude maxillary molars. Furthermore, to evaluate associated root resorption, stability of intrusion, subsequent vertical movement of mandibular molars, cost effectiveness, compliance, patient reported outcomes and adverse events. METHODS: A pre-registered and comprehensive literature search of published and unpublished trials until March 22nd 2023 with no language restriction applied in PubMed/Medline, Embase, Scopus, DOSS, CENTRAL, CINAHL Plus with Full Text, Web of Science, Global Index Medicus, Dissertation and Theses Global, ClinicalTrials.gov, and Trip (PROSPERO: CRD42022310562). Randomized controlled trials involving a comparative assessment of treatment modalities used to intrude maxillary molars were included. Pre-piloted data extraction forms were used. The Cochrane Risk of Bias tool was used for risk of bias assessment, and The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used for certainty of evidence appraisal. RESULTS: A total of 3986 records were identified through the electronic data search, of which 24 reports were sought for retrieval. Of these, 7 trials were included. One trial was judged at high risk of bias, while the others had some concerns. Based on individual small sample studies, maxillary molar intrusion was achieved using temporary anchorage devices (TADs) and rapid molar intruder appliance (RMI). It was also observed to a lesser extent with the use of open bite bionator (OBB) and posterior bite blocks. The molar intruder appliance and the posterior bite blocks (spring-loaded or magnetic) also intruded the lower molars. Root resorption was reported in two studies involving TADs. None of the identified studies involved a comparison of conventional and TAD-based treatments for intrusion of molars. No studies reported outcomes concerning stability, cost-effectiveness, compliance and patient-reported outcomes. Insufficient homogeneity between the included trials precluded quantitative synthesis. The level of evidence was very low. CONCLUSIONS: Maxillary molar intrusion can be attained with different appliances (removable and fixed) and with the use of temporary anchorage devices. Posterior bite blocks (spring-loaded or magnetic) and the RMI offer the additional advantage of intruding the mandibular molars. However, stability of the achieved maxillary molar intrusion long term is unclear. Further high-quality randomized controlled trials are needed.


Malocclusion , Open Bite , Orthodontic Anchorage Procedures , Root Resorption , Humans , Maxilla , Tooth Movement Techniques , Malocclusion/therapy , Open Bite/therapy , Molar
9.
Prog Orthod ; 24(1): 27, 2023 Aug 28.
Article En | MEDLINE | ID: mdl-37635155

OBJECTIVES: This clinical report aims to highlight the factors affecting the clinical success of alveolar ridge mini-implants used for orthodontic anchorage and provide an overview of the biomechanical versatility of this miniscrew and steps involving the proper technique of its placement. METHODS: For this clinical report, charts for 295 patients who had temporary anchorage devices (TADs) were screened. Twenty patients [15 females and 5 males: mean age = 38.15 ± 15.10 years] with 50 alveolar ridge mini-screws were assessed. A descriptive summary of the main factors affecting their clinical success and the technique employed for their placement was comprehensively discussed and illustrated, in addition to the presentation of some clinical cases illustrating their potential clinical uses. RESULTS: The survival duration (7.32 ± 9.01 months) and clinical success of the alveolar ridge mini-implants that failed (19/50) seem to be affected primarily by 2 factors: splinting; none of the splinted mini-implants failed (0/10) compared to (19/40) of the single mini-implants that failed, and the length of the used mini-implant; the average length of the mini-implants that did not fail was 9.23 mm. Additionally, it appears that these mini-implants are biomechanically robust and durable, those that did not fail had an average survival duration of 35.97 ± 19.79 months. CONCLUSION: Ridge mini-implants offer significant biomechanical versatility in patients with partially edentulous ridges needing complex pre-prosthetic orthodontic movements. The presence of splinting and the length of the used mini-implants are factors that might affect the clinical success of the alveolar ridge mini-implants.


Alveolar Process , Movement , Adult , Female , Humans , Male , Middle Aged , Young Adult
10.
Am J Orthod Dentofacial Orthop ; 164(3): e72-e88, 2023 Sep.
Article En | MEDLINE | ID: mdl-37452794

This article focuses on on the presentation and management 9 adult patients who experienced complications because of their maxillary or mandibular fixed retainers 5-33 years after orthodontic treatment. Such complications include the development of an anterior crossbite, open bite, incisal cant, and twist- and x-effects. The detrimental effects on periodontal health were highlighted, especially in the mandibular canines. A range of fixed retainer types was identified, including flexible spiral wire bonded to 4 maxillary or 6 mandibular anterior teeth, rigid wire bonded to mandibular canines only and fiber-reinforced composite fixed retainer. Orthodontic retreatment was necessary in all patients using fixed appliances or clear aligners. Radiographic findings from cone-beam computed tomography or orthopantomogram before and after retreatment are presented when available. Despite the improvement of teeth position clinically, the cone-beam computed tomography scans taken directly after the completion of orthodontic retreatment did not show notable improvement with regards to root proximity to the cortical plates. The prevention of further complications was highlighted, including the use of dual retention, remote monitoring, frequent follow-up appointments and the importance of developing clear guidelines for monitoring patients in retention for treating clinicians and general dentists to promote early detection of adverse changes.


Dental Bonding , Dental Bonding/methods , Orthodontic Retainers/adverse effects , Cuspid/diagnostic imaging , Mandible , Orthodontic Appliances, Fixed , Orthodontic Appliance Design
11.
Am J Orthod Dentofacial Orthop ; 164(6): 793-804, 2023 Dec.
Article En | MEDLINE | ID: mdl-37498253

INTRODUCTION: This study compared treatment efficacy for specific tooth movements between 2 clear aligner systems (Clarity [3M Oral Care Solutions, St Paul, Minn] and Invisalign [Align Technology, San Jose, Calif]). METHODS: The study sample included 47 patients (7 males, 40 females; mean age, 36.57 ± 15.97 years) treated with Invisalign and 37 (4 males, 33 females; mean age, 34.30 ± 16.35 years) treated with Clarity aligners who completed their first set of aligners and had an initial refinement scan. Initial and predicted models were obtained from the initial simulated treatment plan. The first model of the refinement scan was labeled as achieved. SlicerCMF software (version 3.1; http://www.slicer.org) was used to superimpose the achieved and predicted digital models over the initial ones with regional superimposition on the relatively stable first molars. Nine hundred forty teeth in the Invisalign system were measured for horizontal, vertical, and angular movements and transverse width and compared with similar measurements of 740 teeth for the Clarity aligners. The deviation from the predicted was calculated and compared between both systems. RESULTS: The deviation achieved from the predicted was significant between the groups for the mandibular interpremolar and intercanine widths (P <0.05). Clarity aligners significantly undercorrected rotations compared with Invisalign for the mandibular first premolars, mandibular canines, maxillary canines, and maxillary central incisors. There was no statistically significant difference between the groups for the achieved vs predicted movements in the horizontal and vertical planes (P >0.05). CONCLUSIONS: The efficacy of clear aligner therapy systems (Clarity and Invisalign) in treating mild and moderate malocclusions was comparable. Deviation of the achieved movements from the predicted was greatest for rotational and vertical movements.


Malocclusion , Orthodontic Appliances, Removable , Male , Female , Humans , Young Adult , Adult , Middle Aged , Adolescent , Malocclusion/therapy , Software , Treatment Outcome , Incisor , Tooth Movement Techniques
12.
Angle Orthod ; 93(4): 417-426, 2023 07 01.
Article En | MEDLINE | ID: mdl-36912674

OBJECTIVES: To investigate aligner treatment protocols among orthodontists in the United States and Canada and assess the factors influencing clinician choices in aligner systems, treatment protocols, and targeted malocclusions for aligners. MATERIALS AND METHODS: A validated online questionnaire was developed specifically for this research and consisted of three sections. Section 1 evaluated demographics and experience with aligners. Section 2 assessed patient selection and demands and clinician confidence in treating various malocclusions with aligners. Section 3 evaluated treatment protocols used by clinicians. The American Association of Orthodontists Partners in Research Program distributed the survey via e-mail to active members in the United States and Canada. RESULTS: A total of 160 providers completed the survey. Aligners were used by 65.00% of respondents, with the Invisalign system the most popular (81.25%). Aligners were mostly used for adults (97.50%). Tipping was ranked as the easiest movement (1.79 ± 1.35). Extrusion (4.34 ± 1.53) and root movement (4.31 ± 1.27) were ranked as the most difficult. Most were confident treating mild (98.8%) and moderate (82.5%) crowded cases, spacing (96.9%), and anterior crossbite (85%). Of the providers, 58.12% recommended aligners to be changed weekly. Respondents who were confident addressing some of the severe malocclusions were more likely to use Invisalign. CONCLUSIONS: Invisalign is the most popular aligner system, and clinicians seem to be confident using it. Providers are aware of the pitfalls of aligners; they find it challenging to perform root movement and extrusion, and they seem confident treating mild to moderate malocclusions. They avoid complex cases with impactions and severe skeletal problems.


Malocclusion , Orthodontic Appliances, Removable , Adult , Humans , United States , Orthodontists , Malocclusion/therapy , Patient Selection , Surveys and Questionnaires , Tooth Movement Techniques/methods
13.
Orthod Craniofac Res ; 26(1): 81-90, 2023 Feb.
Article En | MEDLINE | ID: mdl-35478265

OBJECTIVES: The objective of the study was to quantify the 3-D location of impacted canines by measuring their linear and angular deviations in relation to adjacent structures and further evaluate impaction severity. METHODS: CBCT images of 314 impacted canines were analysed in the sagittal, coronal and axial planes. Linear and angular measurements were recorded. Canine inclination was identified in coronal and sagittal planes. An evaluation system was constructed for analysis. Upright canine was considered as the appropriate position for fully erupted maxillary canine. Outcomes were compared between right and left sides and by gender. For categorical variables, chi-square tests were used while Mann-Whitney U test was used for continuous variables. Regression models were used to measure severity. RESULTS: Impactions were greater in females (119/207; 57.5%). No significant differences between unilateral (100/207; 49.3%) and bilateral (107/207; 51.7%) (P > 0.05). Out of 314 impactions, 105 (33.4%) were mild, 118 (37.58%) moderate and 91 (28.98%) severe. Severe impactions were primarily buccal (44/ 91; 48.3%), in the occlusal ½ of the adjacent incisor root (38/ 91, 41.7%), mesial to the distal border of central incisor (47/91, 51.6%), with sagittal angle value + >45 ̊ (46/ 91, 50.5%) and mesial tip + >30 ̊ (86/ 91, 94.5%). CONCLUSIONS: Severely impacted canines had their crowns buccal, closer to occlusal plane and mesial to the distal border of the central incisor with greater than 45-degree buccal inclination and greater than 30-degree mesial tip. The sagittal angle can have a significant impact on the severity of impaction. A new classification system was proposed to quantify severity.


Tooth, Impacted , Female , Humans , Male , Cone-Beam Computed Tomography/methods , Cuspid/diagnostic imaging , Incisor , Maxilla/diagnostic imaging , Tooth Root , Tooth, Impacted/diagnostic imaging
14.
Angle Orthod ; 2023 Dec 12.
Article En | MEDLINE | ID: mdl-38319063

OBJECTIVE: To explore retainer protocols and how they are influenced by orthodontic presentation and the nature of occlusal correction. MATERIALS AND METHODS: A prepiloted 45-item online questionnaire targeting orthodontists was developed. The questionnaire covered clinical preferences in terms of retainer type, fabrication, and follow-up during retention; the clinical indications for adjunctive surgical procedures; and the use of active designs to mitigate relapse in specific malocclusions. RESULTS: A total of 206 responses were obtained. The majority of the respondents prescribed maxillary removable and mandibular fixed retainers, with almost half (49.1%) reviewing patients for more than 1 year primarily in person (95.1%). The majority prescribed vacuum-formed (69.6%) 1-mm-thick (44.3%) retainers. Only 37.3% were aware of the type of material used, with polyethylene terephthalate glycol copolymer, followed by polypropylene, being the most common. Hawley retainers were preferred following nonsurgical maxillary expansion and with suboptimal interdigitation. A preference for clear retainers and/or fixed retainers was found in open-bite cases and deep-bite cases. Supracrestal fiberotomy was prescribed commonly (61.1%) for rotations greater than 90°. No retainer was rarely prescribed except after the correction of an anterior crossbite. CONCLUSIONS: Blanket prescription of orthodontic retention is common, with limited awareness of clear plastic retainer materials. Future trials evaluating the effectiveness of approaches for retainer prescription based on the presenting malocclusion would be timely.

15.
Eur J Orthod ; 44(6): 679-689, 2022 12 01.
Article En | MEDLINE | ID: mdl-35801392

BACKGROUND AND OBJECTIVES: The aim of this systematic review and meta-analysis was to evaluate root resorption after maxillary expansion with conventional rapid palatal expansion (RPE) and mini-screw assisted rapid palatal expansion appliances (MARPE) using 2D and 3D radiographic methods and histologic methods of measuring root resorption. SEARCH METHODS AND SELECTION CRITERIA: A search of PubMed/MEDLINE, Scopus, Cochrane Central Register of Controlled Trials, CINAHL, Web of Science, Global Index Medicus, Dissertations & Theses Global, ClinicalTrials.gov registry, ISRCTN Registry, National Research Register, OpenGrey, and the Trip Database was performed. The studies that had analysed root resorption after RPE or MARPE were selected for the systematic review. DATA COLLECTION AND ANALYSIS: The database research, elimination of duplicate studies, data extraction, and risk of bias were performed by the authors independently and in duplication. This systematic review included prospective studies to evaluate root resorption following RPE after tooth-borne (TB), tooth-tissue borne (TTB), bone-borne (BB), and tooth-bone borne (TBB) expansion appliances. RESULTS: A total of 13 prospective trials (six randomized clinical trials and seven non-randomized prospective clinical trials) were identified for inclusion in this systematic review. Histological studies revealed that most teeth experience root resorption on the buccal surfaces after maxillary expansion. MARPE designs with BB and TBB expansion appliances were found to lead to reduced volumetric root resorption than conventional RPE using micro-computed tomography. However, one study using cone beam computed tomography showed no difference in the root resorption with MARPE and RPE designs. CONCLUSIONS AND IMPLICATIONS: Maxillary expansion with RPE can lead to root resorption of maxillary posterior teeth. Root resorption occurs more frequently on buccal surfaces on maxillary posterior teeth. Limited evidence suggests that MARPE may lead to reduced root resorption than RPE. REGISTRATION: This systematic review was conducted following the Cochrane handbook for systematic reviews and interventions and reported according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The protocol was registered at PROSPERO database (https://www.crd.york.ac.uk/prospero/; registration number: PROSPERO CRD42021271181).


Root Resorption , Humans , Root Resorption/diagnostic imaging , Root Resorption/etiology , Palatal Expansion Technique , Prospective Studies , X-Ray Microtomography , Bone Screws
16.
Int Orthod ; 19(1): 37-50, 2021 Mar.
Article En | MEDLINE | ID: mdl-33516650

OBJECTIVE: This systematic review assessed the effects of tooth-borne (TB), tooth-bone-borne (TBB) and bone-borne (BB) micro-implant assisted rapid maxillary expansion (RPE) on airway dimensions and function in young children and adolescents (10- to 17-years-old). MATERIALS AND METHODS: Unrestricted search in 5 electronic databases until June 6th, 2020 was undertaken. This was supplemented with search in 6 additional resources for published, unpublished and ongoing trials up. Randomized (RCT) and non-randomized (Non-RCT) prospective studies that assessed the influence of the mini-screw-assisted rapid palatal expansion (MARPE) approach on airway and breathing in young children and adolescents were included. Two reviewers performed the study selection and data extraction blindly and in duplicate by two authors while disagreements. A random-effects model with a 95% confidence interval (CI), I2 and Chi2 tests were done. ROBINS-I, Cochrane Risk of Bias and GRADE tools were used. Reporting of this review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RESULTS: Overall, 518 articles were retrieved; only 3 studies (2 RCT and one non-RCT) met the inclusion criteria. Both TB RPE and BB RPE improved on a short-term basis the dimensions of the airway, though the difference was not significant (P>0.05). TBB RPE significantly improved nasal airflow [(Mean difference (MD) 52.7 cm3/s, 95% confidence interval (95% CI) 9.0-96.4), P=0.020)], reduced nasal resistance (MD -0.20Pa/cm3, 95% (-0.38)-(-0.02), P=0.028), and changed respiratory muscle strength variables (P>0.05). No correlation was found between the anatomical dimensions of the airway and the functional airway parameters (P>0.05). CONCLUSIONS: The short-term airway volumetric changes secondary to MARPE were not significant. The influence of MARPE appliances on breathing is still not clear. Registration PROSPERO database (CRD42020183340).


Bone Screws , Palatal Expansion Technique/instrumentation , Palate/surgery , Respiration , Adolescent , Child , Databases, Factual , Humans , Maxilla , Middle Aged , Palate/diagnostic imaging
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