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1.
J Ophthalmic Vis Res ; 16(3): 377-383, 2021.
Article En | MEDLINE | ID: mdl-34394866

PURPOSE: There are primarily two techniques for affixing the scleral buckle (SB) to the sclera in the repair of rhegmatogenous retinal detachment (RRD): scleral tunnels or scleral sutures. METHODS: This retrospective study examined all patients with primary RRD who were treated with primary SB or SB combined with vitrectomy from January 1, 2015 through December 31, 2015 across six sites. Two cohorts were examined: SB affixed using scleral sutures versus scleral tunnels. Pre- and postoperative variables were evaluated including visual acuity, anatomic success, and postoperative strabismus. RESULTS: The mean preoperative logMAR VA for the belt loop cohort was 1.05 ± 1.06 (Snellen 20/224) and for the scleral suture cohort was 1.03 ± 1.04 (Snellen 20/214, p = 0.846). The respective mean postoperative logMAR VAs were 0.45 ± 0.55 (Snellen 20/56) and 0.46 ± 0.59 (Snellen 20/58, p = 0.574). The single surgery success rate for the tunnel cohort was 87.3% versus 88.6% for the suture cohort (p = 0.601). Three patients (1.0%) in the scleral tunnel cohort developed postoperative strabismus, but only one patient (0.1%) in the suture cohort (p = 0.04, multivariate p = 0.76). All cases of strabismus occurred in eyes that underwent SB combined with PPV (p = 0.02). There were no differences in vision, anatomic success, or strabismus between scleral tunnels versus scleral sutures in eyes that underwent primary SB. CONCLUSION: Scleral tunnels and scleral sutures had similar postoperative outcomes. Combined PPV/SB in eyes with scleral tunnels might be a risk for strabismus post retinal detachment surgery.

2.
J Heart Lung Transplant ; 40(10): 1145-1152, 2021 10.
Article En | MEDLINE | ID: mdl-34389222

BACKGROUND: Venous thromboembolism (VTE) post lung transplantation is common and has been associated with worse post transplant survival. We report a comprehensive single center review of VTE incidence in the first post transplant year, investigate modifiable risk factors and assess impact on short term outcomes. METHODS: Retrospective review of all lung transplant recipients between August 2016 to 2018 at Temple University Hospital. Patients were followed for 1 year post transplant. All patients were screened for deep venous thrombosis (DVT) within the first 2 weeks with a venous duplex study. Pre transplant, intra operative, post operative variables, and peri-operative practice patterns were compared between VTE positive and VTE negative groups. Logistic regression modeling was used to identify risk factors for early VTE (VTE within 30 days after transplant). RESULTS: A total of 235 patients were included in the study, 58 patients (24.7%) developed a VTE in the first post transplant year. Median time to diagnosis was 17 days. Of the patients with VTE, 76% had an isolated DVT, 13.5 % had an isolated pulmonary embolism (PE), and 10.3% had concomitant DVT and PE. In a multivariate logistic regression model, cardiopulmonary bypass (CPB) (OR 1.93 p = 0.015) and interruption of VTE prophylaxis (OR 4.42 p < 0.0001) were predictive of early VTE. CONCLUSION: VTE post lung transplant is common despite the use of prophylactic anticoagulation. CPB use and interruption of DVT prophylaxis are risk factors for early post transplant VTE. Measures to ensure consistent and uninterrupted prophylaxis may help decrease VTE incidence after lung transplantation.


Lung Transplantation/adverse effects , Postoperative Complications/epidemiology , Transplant Recipients , Venous Thromboembolism/etiology , Aged , Female , Follow-Up Studies , Graft Survival , Humans , Incidence , Male , Pennsylvania/epidemiology , Postoperative Complications/etiology , Retrospective Studies , Risk Factors , Venous Thromboembolism/epidemiology
3.
Br J Ophthalmol ; 105(3): 410-413, 2021 03.
Article En | MEDLINE | ID: mdl-32409294

BACKGROUND/AIMS: Vitrectomy to repair retinal detachment is often performed with either non-contact wide-angle viewing systems or wide-angle contact viewing systems. The purpose of this study is to assess whether the viewing system used is associated with any differences in surgical outcomes of vitrectomy for primary non-complex retinal detachment repair. METHODS: This is a multicenter, interventional, retrospective, comparative study. Eyes that underwent non-complex primary retinal detachment repair by either pars plana vitrectomy (PPV) alone or in combination with scleral buckle/PPV in 2015 were evaluated. The viewing system at the time of the retinal detachment repair was identified and preoperative patient characteristics, intraoperative findings and postoperative outcomes were recorded. RESULTS: A total of 2256 eyes were included in our analysis. Of those, 1893 surgeries used a non-contact viewing system, while 363 used a contact lens system. There was no statistically significant difference in single surgery anatomic success at 3 months (p=0.72), or final anatomic success (p=0.40). Average postoperative visual acuity for the contact-based cases was logMAR 0.345 (20/44 Snellen equivalent) compared with 0.475 (20/60 Snellen equivalent) for non-contact (p=0.001). After controlling for numerous confounding variables in multivariable analysis, viewing system choice was no longer statistically significant (p=0.097). CONCLUSION: There was no statistically significant difference in anatomic success achieved for primary retinal detachment repair when comparing non-contact viewing systems to contact lens systems. Postoperative visual acuity was better in the contact-based group but this was not statistically significant when confounding factors were controlled for.


Contact Lenses , Retinal Detachment/surgery , Scleral Buckling/instrumentation , Surgery, Computer-Assisted/instrumentation , Visual Acuity , Vitrectomy/instrumentation , Equipment Design , Female , Follow-Up Studies , Humans , Male , Middle Aged , Postoperative Period , Retinal Detachment/diagnosis , Retrospective Studies
5.
Ophthalmic Surg Lasers Imaging Retina ; 51(9): 500-505, 2020 09 01.
Article En | MEDLINE | ID: mdl-32955589

BACKGROUND AND OBJECTIVE: Non-causal macular holes (MHs) can occur concurrently with rhegmatogenous retinal detachments (RRDs). The visual outcomes and surgical approach for these eyes are variable. PATIENTS AND METHODS: This was a multi-institutional, retrospective review of all primary retinal detachment surgeries from January 1, 2015, through December 31, 2015. Pre-, intra-, and postoperative metrics were recorded. RESULTS: There were 2,242 eyes that had pars plana vitrectomy for primary RRD, 43 (1.9%) of which had a MH at the time of surgery. The mean postoperative logMAR visual acuity (VA) for the MH cohort was 0.87 ± 0.64 (20/148) and for eyes without a MH was 0.47 ± 0.63 (20/59; P < .0001). The single-surgery re-attachment rate for the MH cohort and no MH cohort was 86.1% and 84.9%, respectively (P = 1.0000). CONCLUSIONS: Patients with noncausal MHs and RRD had significantly worse VA than patients without a MH. Preoperative counseling is imperative in patients with both RRD and MH. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:500-505.].


Macula Lutea/pathology , Retinal Perforations/diagnosis , Visual Acuity , Vitrectomy/methods , Female , Follow-Up Studies , Humans , Male , Middle Aged , Retinal Perforations/surgery , Retrospective Studies , Treatment Outcome
6.
Ophthalmic Surg Lasers Imaging Retina ; 50(3): 153-158, 2019 03 01.
Article En | MEDLINE | ID: mdl-30893448

BACKGROUND AND OBJECTIVE: This study examines whether pars plana vitrectomy (PPV) can achieve a high rate of reattachment in primary rhegmatogenous retinal detachments (RRDs) caused by inferior breaks in phakic eyes. PATIENTS AND METHODS: Patients with primary, phakic RRD with inferior retinal breaks repaired by PPV, endolaser, and gas tamponade between January 2012 and December 2016 were included. RESULTS: Twenty-six eyes from 26 patients were included. Mean patient age was 61.7 years (range: 38 years to 82 years). Thirteen RRDs were macula-involving, with an average of 2.00 ± 0.70 quadrants and 2.50 ± 2.00 breaks. Twenty-three of 26 eyes (88.5%) were attached at postoperative month (POM) 3. Mean logMAR visual acuity was 0.72 ± 0.84 at baseline, 0.65 ± 0.44 at POM 3, 0.44 ± 0.50 at POM 12, and 0.43 ± 0.36 at the final visit. CONCLUSION: Single-surgery success rate of phakic RRD caused by inferior breaks repaired by PPV is high. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:153-158.].


Retinal Detachment/surgery , Retinal Perforations/surgery , Vitrectomy/methods , Adult , Aged , Aged, 80 and over , Female , Humans , Laser Coagulation/methods , Male , Middle Aged , Retrospective Studies , Visual Acuity
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