[Paclitaxel containing chemotherapeutic regimens in first line and reintroduced palliative treatment of metastatic cervical cancer]. / Paklitaxeltartalmú kemoterápiás kombináció metasztatikus cervixtumor elso vonali és reindukciós palliatív kezelésében.

INTRODUCTION: The paclitaxel-carboplatin doublet is an alternative choice in the first line treatment of metastatic or recurrent cervical cancer according to international guidelines. METHOD: The history of seven patients treated with paclitaxel-platinum in the last three years in the Petz Aladár Hospital is reported. A case report, supporting the efficacy of the combination in emergency and in reintroduced settings is presented as well. RESULTS: The average progression-free survival was 10 months. All patients were alive at the time of the submission of the article. CONCLUSION: The results confirm the efficacy of the paclitaxel-carboplatin AUC 5 and the paclitaxel-cisplatin combinations in the treatment of metastatic cervical cancer. Orv Hetil. 2018; 159(24): 974-977.

Modified Heyman packing performed with small number of Simon-Norman catheters.

PURPOSE: Modified Heyman packing method, performed usually with 6-11 flexible catheters is one out of many brachytherapy treatments. We described the insertion and dose planning method, with the use of 4-6 Simon-Norman catheters positioned to the fundus uteri, which is the most frequent source of the endometrial cancer. MATERIAL AND METHODS: We investigated the dose distribution of the main classes of regular catheter insertions with Simon-Norman applicators using dose profiles, obtained in lateral and axial direction at the fundus, and compared with the dose distribution of the Y-shaped catheter arrangements. RESULTS: The insertions with five and six Simon-Norman catheters produced higher dose at the fundus uteri, compared with the Y-shaped applicator. CONCLUSIONS: Insertions performed with small number of catheters permits to perform dosimetry optimisation for each treatment fraction.