RESUMEN
Observational studies consistently show that melanocytic nevus prevalence increases with age and that phenotypic traits are significantly associated with nevus count in children. An observational study of 1,512 children and adolescents from 2010 to 2013 was conducted. Study dermatologists counted the full body, arm, and facial nevi of each participant. Children and their parents were asked to complete a survey to gather data on personal characteristics, pubertal development, and early-life sun exposure. The main aim of the study was to establish pediatric nevus prevalence and its relationship with age, phenotype, sex, menarche, early-life sun exposure, and sun-protection behaviors. Females had a significantly lower nevus count compared with males, but this sex-related difference was significantly modified by menarche. Sun exposure and sun-protection habits were all significantly associated with nevus count; in particular, children who used sunscreen with a sun-protection factor > 30 had a lower nevus count compared with sun-protection factor ≤ 30 sunscreen users. This study shows that sex, menarche status, and sun-protection practices significantly influence nevus count in this pediatric population.
Asunto(s)
Conducta del Adolescente , Conducta Infantil , Menarquia , Nevo Pigmentado/prevención & control , Neoplasias Cutáneas/prevención & control , Luz Solar/efectos adversos , Protectores Solares/farmacología , Adolescente , Niño , Preescolar , Estudios Transversales , Femenino , Humanos , Lactante , Recién Nacido , Italia/epidemiología , Masculino , Nevo Pigmentado/epidemiología , Nevo Pigmentado/etiología , Fenotipo , Prevalencia , Estudios Retrospectivos , Factores Sexuales , Neoplasias Cutáneas/epidemiología , Neoplasias Cutáneas/etiología , Quemadura Solar/complicaciones , Quemadura Solar/prevención & control , Encuestas y CuestionariosRESUMEN
Although, for several decades, the role of ABO blood group antigens has been suspected in the development of cancer, to our knowledge, the association between ABO blood group and the risk of malignant melanoma has not been evaluated yet. We, therefore, examined the relationship between ABO blood group and risk of developing cutaneous malignant melanoma. We retrospectively reviewed 445 patients with a histological diagnosis of malignant melanoma. Blood groups were obtained from medical records. The control group was represented by 38 321 patients. We evaluated the data by investigation with statistical analysis to show a statistically significant increased risk of developing a malignant melanoma in the O Rh-negative group (odds ratio = 1.4). We suggest focus on the melanoma cases belonging to the blood groups O Rh-negative in future studies, because all the clues of this study seem to show a correlation between blood groups and the risk of malignant melanoma among these groups.
Asunto(s)
Sistema del Grupo Sanguíneo ABO/sangre , Melanoma/sangre , Sistema del Grupo Sanguíneo Rh-Hr/sangre , Neoplasias Cutáneas/sangre , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Melanoma/diagnóstico , Oportunidad Relativa , Estudios Retrospectivos , Neoplasias Cutáneas/diagnósticoAsunto(s)
Conocimientos, Actitudes y Práctica en Salud , Melanoma/prevención & control , Neoplasias Cutáneas/prevención & control , Luz Solar/efectos adversos , Adolescente , Niño , Humanos , Italia , Masculino , Melanoma/etiología , Prevención Primaria/organización & administración , Instituciones Académicas/estadística & datos numéricos , Neoplasias Cutáneas/etiología , Estudiantes/estadística & datos numéricos , Protectores Solares/administración & dosificación , Encuestas y CuestionariosAsunto(s)
Hormonas Esteroides Gonadales/metabolismo , Melanoma/metabolismo , Proliferación Celular/efectos de los fármacos , Progresión de la Enfermedad , Antagonistas de Estrógenos/uso terapéutico , Receptor alfa de Estrógeno/metabolismo , Receptor beta de Estrógeno/metabolismo , Humanos , Melanoma/tratamiento farmacológico , Melanoma/patología , Resultado del TratamientoRESUMEN
The incidence of breast carcinoma cutaneous manifestation in patients with breast carcinoma is 23.9%. The most common sites of breast carcinoma cutaneous manifestation are the chest wall and abdomen, but they can occur at the extremities and in the head/neck region. Due the high incidence of breast carcinoma, these cutaneous manifestations are the most common metastases seen by dermatologists. In clinical practice, cutaneous metastases show a wide range of clinical manifestations. Nodules are the most common presentation, but several other patterns are described below.
Asunto(s)
Neoplasias de la Mama/patología , Carcinoma/secundario , Síndromes Paraneoplásicos/etiología , Enfermedades de la Piel/etiología , Neoplasias Cutáneas/secundario , Neoplasias de la Mama/complicaciones , Neoplasias de la Mama/terapia , Carcinoma/complicaciones , Carcinoma/terapia , Femenino , Humanos , Síndromes Paraneoplásicos/patología , Síndromes Paraneoplásicos/terapia , Piel/patología , Enfermedades de la Piel/patología , Enfermedades de la Piel/terapia , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/terapia , Resultado del TratamientoAsunto(s)
Detección Precoz del Cáncer/estadística & datos numéricos , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Tamizaje Masivo/métodos , Melanoma/diagnóstico , Neoplasias Cutáneas/diagnóstico , Femenino , Humanos , Italia/epidemiología , Masculino , Tamizaje Masivo/estadística & datos numéricos , Melanoma/prevención & control , Estudios Prospectivos , Factores de Riesgo , Neoplasias Cutáneas/prevención & controlRESUMEN
BACKGROUND: The diagnosis of squamous cell carcinoma (SCC) is, generally, a clinical diagnosis, but in some cases, when the lesion is pigmented, as in our case, the differential diagnosis between pigmented SCC and other pigmented skin lesions, in particular melanocytic lesions, is difficult. Dermoscopy may improve the early diagnosis of SCC and thus play a role in its preoperative classification. However, its potential role has been hampered so far by the fact that little is known about the dermoscopic features of pigmented SCC. OBJECTIVE: We report the case of a rare pigmented SCC dermoscopically mimicking a melanocytic lesion whose dermoscopic features have been investigated. CONCLUSION: On the basis of the literature and our experience, pigmented SCC can present dermoscopic features typical of melanocytic lesions, such as radial streaks, globules, and homogeneous blue pigmentation, and can lead dermatologists to diagnostic errors.
Asunto(s)
Carcinoma de Células Escamosas/diagnóstico , Dermoscopía , Cara , Neoplasias Cutáneas/diagnóstico , Carcinoma de Células Escamosas/patología , Carcinoma de Células Escamosas/cirugía , Diagnóstico Diferencial , Femenino , Humanos , Persona de Mediana Edad , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/cirugíaAsunto(s)
Dermoscopía , Recurrencia Local de Neoplasia/patología , Neoplasias Cutáneas/secundario , Neoplasias de la Tiroides/patología , Anciano de 80 o más Años , Eritema/etiología , Humanos , Inmunohistoquímica , Neoplasias Pulmonares/secundario , Masculino , Neoplasias Cutáneas/irrigación sanguínea , Neoplasias Cutáneas/patología , Neoplasias de la Tiroides/cirugía , Tiroidectomía , Factores de TiempoRESUMEN
Leiomyosarcomas are rare malignant tumors of smooth muscles. Superficial leiomyosarcoma is generally a disease of middle age, most frequently encountered between 40 and 60 years of age. It is usually diagnosed late or misdiagnosed, since it is a very rare tumor of the head and neck. Awareness of the particularly misleading features of this tumor, especially in elderly patients, is important, as delayed diagnosis is correlated with larger size and invasiveness into contiguous structures, which influence the practicability of radical resection. We present the case of an 81-year-old man with cutaneous leiomyosarcoma on the forehead.