Variables that predict hospital stay and the outcome of Fournier gangrene at King Abdulaziz University Hospital: a retrospective study.

BACKGROUND: The aggressive nature of Fournier gangrene and the associated health issues can result in a more complex clinical course and potentially a longer hospital stay. This study aimed to assess factors that affect the length of hospital stay (LHS) and its relation to the outcome of Fournier gangrene patients. METHODS: A retrospective study was performed at King Abdulaziz University Hospital (KAUH), Saudi Arabia, on patients diagnosed with Fournier gangrene between 2017 and 2023. Data about length of hospital stay (LHS), age, BMI, clinical and surgical data and outcome was obtained. RESULTS: The mean age of the studied patients was 59.23 ± 11.19 years, the mean body mass index (BMI) was 26.69 ± 7.99 kg/m2, and the mean duration of symptoms was 10.27 ± 9.16 days. The most common presenting symptoms were swelling or induration (64%), 88% had comorbidities with diabetes mellitus (DM) (84%), and 76% had uncontrolled DM. of patients, 24% had a poly-microbial infection, with E. coli being the most common (52%). The mean length of hospital stay (LHS) was 54.56 ± 54.57 days, and 24% of patients had an LHS of more than 50 days. Longer LHS (> 50 days) was associated with patients who did not receive a compatible initial antibiotic, whereas shorter LHS was associated with patients who received Impenem or a combination of vancomycin and meropenem as alternative antibiotics following incompatibility. Reconstruction patients had significantly longer LHS and a higher mean temperature. However, none of the studied variables were found to be predictors of long LHS in the multivariate regression analysis. CONCLUSION: Knowledge of the values that predict LHS allows for patient-centered treatment and may be useful in predicting more radical treatments or the need for additional treatment in high-risk patients. Future multicenter prospective studies with larger sample sizes are needed to assess the needed variables and predictors of long LHS.

Primary Urothelial Bladder Cancer in a Young Patient: A Case Report and Review of the Literature.

Despite being a rare condition among young patients, here, we report about a 22-year-old patient with primary urothelial bladder cancer. The patient complained of macroscopic painless hematuria. Transabdominal ultrasound revealed a 2-cm-sized exophytic lesion occupying the left-sided urinary bladder wall. The histologic examination of a specimen obtained during transurethral resection of the bladder tumor showed a superficial low-grade urothelial bladder tumor, pTa G1. Close follow-up with regular cystoscopies and urine cytological examinations is the cornerstone in the disease's therapy. Underlying genetic factors may predispose to the development of the disease, which may require further investigations.

Primary chondrosarcoma of the penis in a young patient: A case report and review of the literature.

INTRODUCTION: Primary chondrosarcoma of the penis is rare. We present a case of primary chondrosarcoma of the penis in a young patient. CASE PRESENTATION: A 35-year-old man presented with a painless mass at the base of his penis for the past 6 months. Incisional biopsy of the lesion revealed a chondrosarcoma. Pelvic magnetic resonance imaging and computed tomography of the thorax, abdomen, and pelvis ruled out a primary lesion in the bones and soft tissues. The patient rejected total penectomy and decided to start chemoradiotherapy followed by local tumor resection. CONCLUSION: Primary chondrosarcoma of the penis is rare. Interdisciplinary management plays an important role in planning the therapy for rare tumors. A combined chemoradiation therapy can be followed by penis-preserving surgery to improve the quality of life in young patients with proximal penile tumors.