Disseminated mycobacterium genavense infection with central nervous system involvement in an HIV patient: a case report and literature review.

BACKGROUND: Immunodeficient patients, particularly HIV patients, are at risk of opportunistic infections. Nontuberculous mycobacteria can cause severe complications in immunodeficient patients. CASE PRESENTATION: We describe a 57-year-old HIV patient, primarily presented with coughs and constitutional symptoms, with a unique Mycobacterium genavense abdominal, pulmonary, and central nervous system infection, accompanied by intracranial masses. CONCLUSION: The diagnosis of NTM, including M. genavense, must always be considered by clinicians in immunodeficient patients, especially those with HIV, who have a compromised immune system.

Optimized Er: YAG Laser Irradiation Distance to Achieve the Strongest Bond Strength Between Orthodontic Brackets and Zirconia-Ceramics.

Introduction: In recent decades zirconium oxide has been introduced in the field of dentistry as a high-strength ceramic. Unlike its mechanical advantages, however, due to its inert chemical properties, it bonds poorly to other substrates, so improving bonding strength to an adhesive material is necessary. Methods: In this experimental study, 70 ceramic zirconia blocks were prepared and distributed randomly among 7 groups. Then the shear bond strengths were determined and the samples were examined by a scanning electron microscope (SEM). Statistical analysis was performed by one-way ANOVA and multiple Tukey comparisons. Results: One-way analysis of variance (ANOVA) showed that laser irradiation distance has a significant effect on orthodontics brackets bond strength to zirconia-ceramics. Based on the Tukey post hoc test, each group was compared with other groups and the contact mode and 2 mm distance groups showed significantly higher bond strength than other groups (P value <0.05). Conclusion: Orthodontic bracket bond strength to zirconia-ceramics will be reduced by increasing Er: YAG laser irradiation distance from samples. The highest bond strength will be achieved when laser irradiation distance is 2 mm or when the laser beam is in contact with samples.