Antimicrobial efficacy of phyto-synthesized silver nanoparticles using aqueous leaves extract of Rosamarinus officinalis L.

The current research investigation demonstrated that the aqueous leaves extract of Rosamarinus officinalis possesses cardinal phyto-chemicals to fabricate AgNPs in an eco-friendly way. The phyto-synthesized AgNPs were characterized to be stable, monodispersed, polycrystalline and mostly spheroidal in conformation. The nano-spheriods were observed to be 25-75 nm in diameter, displaying λmax peak at 430 nm. From the comparative antimicrobial investigations, it was observed that AgNPs manifested tremendous bactericidal properties against all test organisms particularly S. epidermis (89%), S. aureus (84%) and K. pneumonia (84%), owing least MIC values of 40µL. The aced fungicidal activity was also exhibited by AgNPs against all fungal test species particularly C. herbarum (90%), A. flavus (85%), R. stolonifer (85%) and C. jadinii (85%). In contrast to AgNPs, all crude ethanolic, aqueous, methanolic and n-hexanoic extracts manifested less to moderate antimicrobial activity against all test micro-organisms with three-fold escalating MIC values i.e., 160µL.

Exploring the therapeutic potential and bio-evaluation of muesli (Chlorophytum borivilianum) for the management of postprandial glucose management in healthy and diabetic female subjects.

Muesli and cereal based breakfast contain generous amounts of fiber that are helpful in the management of blood glucose levels. Muesli contains ß-glucans that ensure gradual rise in blood glucose levels. Muesli also limits the absorption of glucose by making it unavailable. This study explored the effect of muesli in the management of postprandial blood glucose levels. 15 healthy and 15 diabetic females were offered muesli meal after 8h fasting. Fasting blood glucose levels and blood glucose level 30 and 60 minutes after meal were measured. Results of study showed that muesli brought a gradual rise in blood sugar level. Healthy females showed fasting sugar (92.17±11.27), after 30 minutes (110.87±13.85) and after 60 minutes (114.25±15.67) while diabetic females showed fasting sugar (113.25±10.87), after 30 minutes (117.83±18.74) and after 60 minutes (118.26±17.85). The nutritional profile of muesli showed that it contained 202 kcal of energy, 32.7g of carbohydrates, 9g of fiber, 12.4g of protein and 2.5g of fats. It also contained 5.1g of ß-glucans. Muesli found to be effective in the management of postprandial blood glucose levels in healthy and diabetic populations.