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1.
Radiats Biol Radioecol ; 44(6): 637-52, 2004.
Artículo en Ruso | MEDLINE | ID: mdl-15700803

RESUMEN

Investigation of application of chromosome aberrations of lymphocytes in peripheral blood for biological dosimetry purposes in remote (up to 40 years) period after acute exposure to doses of 1 Gy and more was carried out. The comparative analysis of frequency of unstable and stable (using FISH and G-banding methods) aberrations was performed for 24 subjects accidentally exposed to radiation on nuclear submarines during 1961-1985. Statistically significant increasing of frequency of dicentrics and centric rings was determined in the exposed subjects in remote period after exposure to compare with controls. Their sum frequency in the exposed group varied depending on ARS heaviness from 0.1 to 1.0 aberrations per 100 cells. In control group it was from 0 to 0.2 correspondingly. Translocation frequency (complete + incomplete) fixed by FISH method (2, 4, and 12 chromosomes) varied within the limits of 0.2-16.0 for exposed subjects and 0.3-1.26 translocations per genome per 100 cells for controls. Some examined persons (5 subjects) exposed to accident in 1985 had results of analysis of unstable chromosome aberration in acute period after exposure that allow to estimate obtained doses by dicentrics frequency which having good correlation with ARS heaviness. Individual dosed using traslocation frequency were defined retrospectively in 11 from 21 exposed persons. They correlate with calculated physics doses and doses estimated by haematolotical parameters in acute period and also doses obtained by ESR spectroscopy of tooth enamel in remote period.


Asunto(s)
Aberraciones Cromosómicas , Exposición a Riesgos Ambientales , Liberación de Radiactividad Peligrosa , Radiometría/métodos , Bandeo Cromosómico , Cromosomas Humanos/genética , Análisis Citogenético/métodos , Humanos , Hibridación Fluorescente in Situ , Linfocitos/sangre , Linfocitos/citología , Linfocitos/efectos de la radiación , Dosis de Radiación , Radiación Ionizante
3.
Voen Med Zh ; 317(10): 51-4, 80, 1996 Oct.
Artículo en Ruso | MEDLINE | ID: mdl-9027095

RESUMEN

By one of ways of perfection of means and methods of the radioactive-hygiene irradiation doses control of personnel and radioactive contamination control of environment in the regions of dislocation of radioactive dangerous objects is creation of mobile complexes of the radioactive hygiene control, forming basis of mobile medical-economic complex (Zhiliaev E. G., Volodin A. S., Gavriutin V. M., 1995). In article a general characteristic of such complexes is given and example of practical use of one of typical mobile radiologic laboratories of domestic production as analogue of a mobile complex of the radioactive hygiene control.


Asunto(s)
Física Sanitaria/instrumentación , Medicina Militar/instrumentación , Medicina Naval/instrumentación , Protección Radiológica/instrumentación , Humanos , Laboratorios , Centrales Eléctricas , Federación de Rusia , Navíos
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