Reactive changes with microfilaria in a suspected metastatic axillary lymph node on positron emission tomography-computed tomography in breast malignancy: An interesting finding.

Positron emission tomography-computed tomography (PET-CT) has evolved as an important diagnostic tool in the diagnosis and management of breast carcinoma. PET/CT can help in staging as well as detecting metastases to mediastinal, axillary, and internal mammary nodes. However, PET-CT is not useful in differentiating between inflammation and malignancy.

Parasitic Leiomyoma on PET-CT in A Suspected Case of Uterine Sarcoma - Report on Diagnosis and Management.

This case is a very good example of how a multimodality approach was taken in diagnosis and management of patient with suspected uterine sarcoma, which turned out to be uterine leiomyoma with parasitic leiomyoma mimicking the pararenal deposit. There has been an increased use of fluorodeoxyglucose avid positron emission tomography-computed tomography in pelvic malignancies, especially in the cases where there is suspected extrapelvic spread. It was an interesting finding of parasitic leiomyoma, which can be easily thought to be as deposit/mass in a patient with pelvic malignancy.

Sternal Foramina in Patient with Hepatocellular Carcinoma: A Diagnostic Dilemma on Bone Scan.

Presenting known treated case of hepatocellular carcinoma, complaining of non specific backache. 99mTc methylene diphosphonate bone scan showed photopenic area in sternal body, which could be easily thought of osteolytic metastasis from hepatocellular carcinoma; however CT scan revealed it to be sternal foramina- a normal variant of sternum. The possibility of a sternal foramen should be mentioned to the clinician because infiltration, biopsy or acupuncture of this area may lead to fatal cardiac complications. Knowledge of the existence of such anatomic variants is important to avoid misdiagnosis as an osteolytic process.

Granulomatous reaction in a patient with lung cancer: should we treat it?

In TB endemic regions, granulomatous inflammation in the samples from a tumour in the lung or in the draining lymph nodes will not be sufficient to diagnose TB as granulomas can also arise as a reaction to tumour cells http://ow.ly/tOTm30kSFAY.

Cervical and uterine metastasis from carcinoma of breast diagnosed by PET/CT: an unusual presentation.

A 44-year-old apparently healthy woman presented with a 5-month history of intermittent vaginal bleeding. Clinical examination raised the suspicion of cervical neoplasia which was confirmed to be a metastatic adenocarcinoma on subsequent histopathological evaluation. An F-18 FDG PET/CT scan performed soon after revealed increased uptake in the cervix, extending upwards into the endometrial cavity. Additionally, small FDG avid spiculated soft tissue density masses were visualized in bilateral breast parenchyma, which proved to be lobular carcinoma on sonomammography followed by histopathology. Multiple lytic FDG avid skeletal metastases were also noted. Endometrial biopsy showed infiltrative malignant tumor with cytologic features similar to those observed in the breast biopsy specimen. The entire spectrum of findings pointed to a diagnosis of bilateral lobular carcinoma with uterine, cervical, and skeletal metastasis. Metastasis to the uterus and cervix from a breast primary is extremely rare. Most cases have been diagnosed in the follow-up of known cases of breast carcinoma. Our case is unique in that the patient, who had no prior history of breast carcinoma, was suspected to have a breast primary with cervical and uterine metastasis, based on the PET/CT findings.