1.
Chem Commun (Camb)
; 52(58): 9067-70, 2016 Jul 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26890187
RESUMEN
Incorporation of early druggability assessment in the drug discovery process provides a means to prioritize target proteins for high-throughput screening. We present chemical fragment arrays as a method that is capable of determining the druggability of a given target with low protein and compound consumption, enabling rapid decision making during early phases of drug discovery.