[PSA doubling time as a new diagnostic and prognostic method for prostate cancer]. / El tiempo de doblaje de PSA como nuevo método diagnóstico y pronóstico del cáncer de próstata.

OBJECTIVES: To review the value of PSA kinetics in the diagnosis and prognosis of prostate cancer. METHODS: Review of the literature through a Medline search. CONCLUSIONS: A pre-tretament PSAV value >2ng/ ml/yr is a risk factor for increased mortality from prostate cancer after surgery or radiation therapy. A PSADT<3ms is indicative of reduced survival after treatment. For patients with PSA recurrence after surgery a PSADT> 10 is more likely associated with local recurrence.