Reporte de caso: Miofibroblastoma mamario paratesticular / Case report: Paratesticular mammary myofibroblastoma

RESUMEN Existe una variedad de tumores epiteliales, mesoteliales y de tejidos blandos que pueden desarrollarse en la red testicular y paratesticular. Se presenta el caso clínico de paciente con tumoración paratesticular derecha: Miofibroblastoma Mamario Paratesticular. Importante recalcar la variedad de origen embrionario para el desarrollo de estos tumores, así como el diagnóstico oportuno para el tratamiento y seguimiento resolutivo.

ABSTRACT There is a variety of epithelial, mesothelial, and soft tissue tumors that can develop in the testicular and paratesticular area. We present the case of a patient with a right paratesticular tumor that was diagnosed as paratesticular mammary myofibroblastoma. It is important to emphasize the embryonic origin variety for the development of these tumors, as well as having a timely diagnosis for treatment and decisive follow-up.

Alopecia and severity of COVID-19: a cross-sectional study in Peru.

The aim of this study was to determine the relationship between COVID-19 severity and androgenic alopecia in patients hospitalized in the Surgery Service of Honorio Delgado Espinoza Hospital in Arequipa, Peru. A cross-sectional study was performed in male patients with a diagnosis of COVID-19. Alopecia, clinical characteristics, treatment, and evolution were collected. In all, 98 patients were included; median age was 55 years old (range 18-89), 32.7% with comorbidities, and 45.9% with androgenic alopecia. The severity of COVID-19 infection was moderate to severe in 13.2% of patients without alopecia, and in 88.9% of patients with alopecia (p>0.001). In the logistic regression model analysis, patients with alopecia had a higher risk of presenting moderate to severe symptoms due to SARS-CoV-2 infection (OR: 80.2; 95% CI 16.2-397.7). In conclusion, the severity of infection was statistically significant in patients over 60 years old and those with alopecia.

Consequences of diverse evolutionary processes on american genetic gradients of modern humans.

European genetic gradients of modern humans were initially interpreted as a consequence of the demic diffusion of expanding Neolithic farmers. However, recent studies showed that these gradients may also be influenced by other evolutionary processes such as population admixture or range contractions. Genetic gradients were observed in the Americas, although their specific evolutionary causes were not investigated. Here we extended the approach used to study genetic gradients in Europe to analyze the influence of diverse evolutionary scenarios on American genetic gradients. Using extensive computer simulations, we evaluated the impact of (i) admixture between expansion waves of modern humans, (ii) the presence of ice-sheets during the last glacial maximum (LGM) and (iii) long-distance dispersal (LDD) events, on the genetic gradients (detected by principal component analysis) of the entire continent, North America and South America. The specific simulation of North and South America showed that genetic gradients are usually orthogonal to the direction of range expansions-either expansions from Bering or posterior re-expansions to recolonize northern regions after ice sheets melting-and we suggest that they result from allele surfing processes. Conversely, our results on the entire continent show a northwest-southeast gradient obtained with any scenario, which we interpreted as a consequence of isolation by distance along the long length of the continent. These findings suggest that distinct genetic gradients can be detected at different regions of the Americas and that subcontinent regions present gradients more sensible to evolutionary and environmental factors (such as LDD and the LGM) than the whole continent.

A phylogenetic study of Laeliinae (Orchidaceae) based on combined nuclear and plastid DNA sequences.

BACKGROUND AND AIMS: Laeliinae are a neotropical orchid subtribe with approx. 1500 species in 50 genera. In this study, an attempt is made to assess generic alliances based on molecular phylogenetic analysis of DNA sequence data. METHODS: Six DNA datasets were gathered: plastid trnL intron, trnL-F spacer, matK gene and trnK introns upstream and dowstream from matK and nuclear ITS rDNA. Data were analysed with maximum parsimony (MP) and Bayesian analysis with mixed models (BA). KEY RESULTS: Although relationships between Laeliinae and outgroups are well supported, within the subtribe sequence variation is low considering the broad taxonomic range covered. Localized incongruence between the ITS and plastid trees was found. A combined tree followed the ITS trees more closely, but the levels of support obtained with MP were low. The Bayesian analysis recovered more well-supported nodes. The trees from combined MP and BA allowed eight generic alliances to be recognized within Laeliinae, all of which show trends in morphological characters but lack unambiguous synapomorphies. CONCLUSIONS: By using combined plastid and nuclear DNA data in conjunction with mixed-models Bayesian inference, it is possible to delimit smaller groups within Laeliinae and discuss general patterns of pollination and hybridization compatibility. Furthermore, these small groups can now be used for further detailed studies to explain morphological evolution and diversification patterns within the subtribe.

Factores relacionados con el ingreso domiciliario en edad pediátrica en el Consejo Popular Sur del municipio Morón / Factors related to the domiciliary entrance in pediatrica age in the South Popular Council of the Morón municipality

Se realizó un estudio observacional descriptivo para identificar algunas variables relacionadas con el ingreso domiciliario en la edad pediátrica en el Consejo Popular Sur del municipio Morón, en el período comprendido entre el 1ro de Enero al 31 de Diciembre del año 2004, encontrándose que el 50.4 porciento de nuestros pacientes ingresados pertenecieron al sexo masculino, e igual porciento al grupo de menores de un año de edad; las infecciones respiratorias agudas fueron las afecciones que motivaron mayor numero de ingresos(46.8 porciento) en ambos sexos; las Infecciones Respiratorias Altas(IRA) fueron las que predominaron con un 32.8 porciento y dentro de ellas el Catarro Común; la estadía de nuestros ingresos domiciliarios estuvo en un 65.8 porciento entre 6 10 días y resultaron curados el 96.5 porciento de nuestros pacientes al egreso. (AU)

Violencia intrafamiliar y salud mental del adolescente / Intrafamiliar violence and mental health of the adolescent

Se realizó una investigación observacional descriptiva con los adolescentes de 11 a 15 años de edad pertenecientes al consultorio 17 del Policlínico Comunitario Docente Sur de Morón, en el período comprendido desde junio del año 2003 hasta enero del 2004; con el objetivo de identificar la presencia de violencia intrafamiliar y algunos elementos del estado de salud mental de los adolescentes. Esperamos que este programa mejore los conocimientos de los adolescentes y sus padres sobre la violencia y se logre una adecuada salud familiar(AU)

Violencia familiar en adolescentes / Familiar violence in adolescents

Se realizó una investigación observacional descriptiva con los adolescentes de 11 a 15 años del Consultorio Médico de la familia No. 35 del Policlínico Docente Comunitario Sur de Morón, en el período comprendido desde septiembre del 2003 a marzo del 2004, el mayor porciento de los adolescentes convivía con la madre y padrastro y las situaciones de violencia presenciadas con mas frecuencia fueron las discusiones entre los miembros de la familia. El 94,4 porciento de los adolescentes refirió haber sufrido violencia psicológica. La actitud asumida por los padres ante un problema del adolescente fue dedicar un tiempo para conversar con ellos. La situación “al hablarle me grita y me insulta” predominó como una manifestación de violencia de los adolescentes referida por la madre (AU)