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1.
Neurol India ; 72(2): 272-277, 2024 Mar 01.
Article En | MEDLINE | ID: mdl-38691469

BACKGROUND: Incidental diagnosis of saccular aneurysms is more common with the advent of imaging techniques. Because of the severe morbidity and mortality that they can cause, treatment is chased for them, either microsurgical treatment or endovascular, even when they are diagnosed incidentally. Carotid cave aneurysms are rare, and they seem to have a more benign course compared to other intracranial aneurysms, probably related to the physical enveloping effect of the surrounding structures. Yet, their microsurgical treatment is a serious challenge technically for the neurosurgeon, with its severe morbidity and mortality for the patient. Endovascular techniques have their risks, too. PURPOSE: In this paper, we analyzed and presented our series of incidentally diagnosed carotid cave aneurysms. MATERIALS AND METHODS: The age, gender of patients, the size, laterality, and MR angiographic follow-up of aneurysms were reported. Their clinical results were noted. RESULTS: Fifty-six patients who had incidentally been diagnosed with 59 carotid cave aneurysms were followed up. No patient was microsurgically treated, but 15 patients had endovascular treatment for 15 aneurysms. The mean size of 15 treated aneurysms was 4.6 ± 2.1 (range = 2-10) mm, and it was 3.0 ± 1.5 (range = 1.7-10) mm for the untreated aneurysms (n = 44). There was no significant difference between the follow-up times of the treated and untreated groups (P = 0.487). The median follow-up of 59 aneurysms in 56 patients was 52 (mean = 49.6 ± 27.9, range = 1-124) months, with a total follow-up of 244 aneurysm years. None of the patients had subarachnoid hemorrhage related to carotid cave aneurysms during follow-up, and none of the aneurysms had shown growth. Two patients who had endovascular treatment had ischemic complications with minor neurologic deficits. CONCLUSION: Follow-up can be a reasonable option for the incidental aneurysms that are located and confined to the carotid cave. Additionally, TOF might be a reliable method for follow-up imaging of carotid cave aneurysms.


Endovascular Procedures , Incidental Findings , Intracranial Aneurysm , Humans , Male , Female , Intracranial Aneurysm/surgery , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/therapy , Middle Aged , Endovascular Procedures/methods , Aged , Adult , Carotid Artery Diseases/surgery , Carotid Artery Diseases/diagnostic imaging , Carotid Artery, Internal/surgery , Carotid Artery, Internal/diagnostic imaging , Carotid Artery, Internal/pathology
2.
Diagn Interv Radiol ; 30(2): 91-98, 2024 03 06.
Article En | MEDLINE | ID: mdl-37888786

PURPOSE: To compare images generated by synthetic diffusion-weighted imaging (sDWI) with those from conventional DWI in terms of their diagnostic performance in detecting breast lesions when performing breast magnetic resonance imaging (MRI). METHODS: A total of 128 consecutive patients with 135 enhanced lesions who underwent dynamic MRI between 2018 and 2021 were included. The sDWI and DWI signals were compared by three radiologists with at least 10 years of experience in breast radiology. RESULTS: Of the 82 malignant lesions, 91.5% were hyperintense on sDWI and 73.2% were hyperintense on DWI. Of the 53 benign lesions, 71.7% were isointense on sDWI and 37.7% were isointense on DWI. sDWI provides accurate signal intensity data with statistical significance compared with DWI (P < 0.05). The diagnostic performance of DWI and sDWI to differentiate malignant breast masses from benign masses was as follows: sensitivity 73.1% [95% confidence interval (CI): 62-82], specificity 37.7% (95% CI: 24-52); sensitivity 91.5% (95% CI: 83-96), specificity 71.7% (95% CI: 57-83), respectively. The diagnostic accuracy of DWI and sDWI was 59.2% and 83.7%, respectively. However, when the DWI images were evaluated with apparent diffusion coefficient mapping and compared with the sDWI images, the sensitivity was 92.68% (95% CI: 84-97) and the specificity was 79.25% (95% CI: 65-89) with no statistically significant difference. The inter-reader agreement was almost perfect (P < 0.001). CONCLUSION: Synthetic DWI is superior to DWI for lesion visibility with no additional acquisition time and should be taken into consideration when conducting breast MRI scans. The evaluation of sDWI in routine MRI reporting will increase diagnostic accuracy.


Breast Neoplasms , Magnetic Resonance Imaging , Humans , Female , Retrospective Studies , Magnetic Resonance Imaging/methods , Diffusion Magnetic Resonance Imaging/methods , Breast/diagnostic imaging , Breast Neoplasms/diagnostic imaging , Sensitivity and Specificity
3.
Curr Med Imaging ; 2023 Oct 20.
Article En | MEDLINE | ID: mdl-37881082

INTRODUCTION: Castleman's disease is an extremely rare disease in the abdomen region characterized by benign lymphoepithelial proliferation. CASE PRESENTATION: We report a case of a 63-year-old female who presented with abdominal pain. Abdominal CT Angio and dynamic contrast-enhanced abdominal MRI revealed a mass lesion showing markedly contrast enhancement, no vascular invasion sign, and diffusion restriction lesion in the truncus coelicus bifurcation region. The mass was surgically resected completely. Pathological evaluation showed a hyaline-vascular type of Castleman's disease. CONCLUSION: Castleman's disease should be kept in mind in the differential diagnosis of an isolated intra-abdominal mass.

4.
Eur J Radiol ; 165: 110923, 2023 Aug.
Article En | MEDLINE | ID: mdl-37320883

BACKGROUND: The Prostate Imaging Quality (PI-QUAL) score is the first step toward image quality assessment in multi-parametric prostate MRI (mpMRI). Previous studies have demonstrated moderate to excellent inter-rater agreement among expert readers; however, there is a need for studies to assess the inter-reader agreement of PI-QUAL scoring in basic prostate readers. OBJECTIVES: To assess the inter-reader agreement of the PI-QUAL score amongst basic prostate readers on multi-center prostate mpMRI. METHODS: Five basic prostate readers from different centers assessed the PI-QUAL scores independently using T2-weighted images, diffusion-weighted imaging (DWI) including apparent diffusion coefficient (ADC) maps, and dynamic-contrast-enhanced (DCE) images on mpMRI data obtained from five different centers following Prostate Imaging-Reporting and Data System Version 2.1. The inter-reader agreements amongst radiologists for PI-QUAL were evaluated using weighted Cohen's kappa. Further, the absolute agreements in assessing the diagnostic adequacy of each mpMRI sequence were calculated. RESULTS: A total of 355 men with a median age of 71 years (IQR, 60-78) were enrolled in the study. The pair-wise kappa scores ranged from 0.656 to 0.786 for the PI-QUAL scores, indicating good inter-reader agreements between the readers. The pair-wise absolute agreements ranged from 0.75 to 0.88 for T2W imaging, from 0.74 to 0.83 for the ADC maps, and from 0.77 to 0.86 for DCE images. CONCLUSIONS: Basic prostate radiologists from different institutions provided good inter-reader agreements on multi-center data for the PI-QUAL scores.


Prostate , Prostatic Neoplasms , Male , Humans , Middle Aged , Aged , Prostate/diagnostic imaging , Prostatic Neoplasms/diagnostic imaging , Retrospective Studies , Magnetic Resonance Imaging/methods , Diffusion Magnetic Resonance Imaging/methods
5.
Eur J Radiol ; 165: 110924, 2023 Aug.
Article En | MEDLINE | ID: mdl-37354768

BACKGROUND: Although systems such as Prostate Imaging Quality (PI-QUAL) have been proposed for quality assessment, visual evaluations by human readers remain somewhat inconsistent, particularly among less-experienced readers. OBJECTIVES: To assess the feasibility of deep learning (DL) for the automated assessment of image quality in bi-parametric MRI scans and compare its performance to that of less-experienced readers. METHODS: We used bi-parametric prostate MRI scans from the PI-CAI dataset in this study. A 3-point Likert scale, consisting of poor, moderate, and excellent, was utilized for assessing image quality. Three expert readers established the ground-truth labels for the development (500) and testing sets (100). We trained a 3D DL model on the development set using probabilistic prostate masks and an ordinal loss function. Four less-experienced readers scored the testing set for performance comparison. RESULTS: The kappa scores between the DL model and the expert consensus for T2W images and ADC maps were 0.42 and 0.61, representing moderate and good levels of agreement. The kappa scores between the less-experienced readers and the expert consensus for T2W images and ADC maps ranged from 0.39 to 0.56 (fair to moderate) and from 0.39 to 0.62 (fair to good). CONCLUSIONS: Deep learning (DL) can offer performance comparable to that of less-experienced readers when assessing image quality in bi-parametric prostate MRI, making it a viable option for an automated quality assessment tool. We suggest that DL models trained on more representative datasets, annotated by a larger group of experts, could yield reliable image quality assessment and potentially substitute or assist visual evaluations by human readers.


Deep Learning , Prostatic Neoplasms , Male , Humans , Prostate/diagnostic imaging , Feasibility Studies , Prostatic Neoplasms/diagnostic imaging , Magnetic Resonance Imaging/methods
6.
Insights Imaging ; 14(1): 48, 2023 Mar 20.
Article En | MEDLINE | ID: mdl-36939953

OBJECTIVE: To investigate whether commercially available deep learning (DL) software improves the Prostate Imaging-Reporting and Data System (PI-RADS) scoring consistency on bi-parametric MRI among radiologists with various levels of experience; to assess whether the DL software improves the performance of the radiologists in identifying clinically significant prostate cancer (csPCa). METHODS: We retrospectively enrolled consecutive men who underwent bi-parametric prostate MRI at a 3 T scanner due to suspicion of PCa. Four radiologists with 2, 3, 5, and > 20 years of experience evaluated the bi-parametric prostate MRI scans with and without the DL software. Whole-mount pathology or MRI/ultrasound fusion-guided biopsy was the reference. The area under the receiver operating curve (AUROC) was calculated for each radiologist with and without the DL software and compared using De Long's test. In addition, the inter-rater agreement was investigated using kappa statistics. RESULTS: In all, 153 men with a mean age of 63.59 ± 7.56 years (range 53-80) were enrolled in the study. In the study sample, 45 men (29.80%) had clinically significant PCa. During the reading with the DL software, the radiologists changed their initial scores in 1/153 (0.65%), 2/153 (1.3%), 0/153 (0%), and 3/153 (1.9%) of the patients, yielding no significant increase in the AUROC (p > 0.05). Fleiss' kappa scores among the radiologists were 0.39 and 0.40 with and without the DL software (p = 0.56). CONCLUSIONS: The commercially available DL software does not increase the consistency of the bi-parametric PI-RADS scoring or csPCa detection performance of radiologists with varying levels of experience.

7.
J Comput Assist Tomogr ; 47(4): 561-568, 2023.
Article En | MEDLINE | ID: mdl-36944155

METHODS: A retrospective analysis was conducted on 75 lesions in 50 patients with pathologically proven breast cancer who underwent MRI in prone and supine positions between December 2019 and December 2020. The transverse, anteroposterior, and craniocaudal dimensions (in millimeters) of the tumor in the x -, y -, and z -axes were measured. Distances from the center of the tumor to the chest wall and the adjacent skin were measured on transverse and reformatted sagittal images. In cases where multifocal lesions were present, the transverse, anteroposterior, and craniocaudal distances between the tumor centers in the x -, y -, and z -axes were measured. Differences between measurements in supine and prone MRI were evaluated with the Mann-Whitney U and the Wilcoxon tests. P values of less than 0.05 were considered to indicate a statistically significant difference. RESULTS: The analysis revealed 31 MRIs with 1 and 20 with multifocal lesions. The x -axis dimension of the lesions in prone and supine positions did not significantly differ ( P = 0.198) between the 2 positions. A significant difference in the y - and z -axes dimensions was observed between the prone and supine position ( P = 0.00 for both). The distance from the tumor to the chest wall and the adjacent skin showed significant difference ( P = 0.00 for both). For multifocal lesions, the distance between the lesions showed a significant difference on the y -axis ( P = 0.00). CONCLUSIONS: This study showed a significant difference in the tumor size, location, and tumor-to-tumor distances due to change of patient position, from the standard prone MRI to the supine position in the operating room, resulting in distortion, spatial repositioning, and convergence of the lesions. Supine MRI may be considered in providing a less extensive surgery.


Breast Neoplasms , Humans , Female , Retrospective Studies , Supine Position , Prone Position , Breast Neoplasms/pathology , Magnetic Resonance Imaging/methods
8.
Indian J Orthop ; 57(1): 102-109, 2023 Jan.
Article En | MEDLINE | ID: mdl-36660484

Aim: Coal miners are more prone to musculoskeletal injuries to their knees due to specific repetitive movements while working in the seams. We aimed to identify the kinds of and quantify traumatic musculoskeletal injuries to the knee in the coal miners. Methods: A retrospective observational analysis of all consecutive emergency admissions of the coal miners with occupational knee injuries between January 2018 and December 2020 was performed. A total of 94 knee trauma events in 79 knees of 76 patients were analyzed in the study. Musculoskeletal injuries of the meniscal and ligamentous/tendinous structures were identified using magnetic resonance imaging of the affected knees. Results: The medial meniscal and the anterior cruciate ligament injuries were detected in 72.3% and 51.1% of the events, respectively. Grade 2 and 3 medial meniscal injuries were the most common grades (39.7% and 41.2%, respectively). For the anterior cruciate ligament injuries, grade 2 was the most common (56.3%). In 48.9% of the cases, we detected bony bruise/edema in the tibial plateau (52.2%), and the condyles of the femur (45.7%) were almost equally affected. Intraarticular effusions appeared in 59.6% of the cases. Conclusions: Our findings provide detailed identification of the injuries seen in the coal miners. The medial meniscus and the anterior cruciate ligament are the most frequently injured structures.

9.
Urol J ; 20(1): 34-40, 2022 Dec 25.
Article En | MEDLINE | ID: mdl-36528799

BACKGROUND: The aim of this study was to investigate the diagnostic performance of mpMRI for detecting cribriform pattern prostate cancer. MATERIALS AND METHODS: This study retrospectively enrolled 33 patients who were reported cribriform pattern prostate cancer at final pathology. The localization, grade and volumetric properties of the dominant tumors and areas with cribriform pattern at the final pathological specimens were recorded and the diagnostic value of mpMRI was evaluated on the basis of the cribriform morphology detection rate. It was analyzed using Wilcoxon test, the Chi-square test and Fisher's Exact test. The significance level (P-value) was set at .05 in all statistical analyses. RESULTS: A total of 58 prostate cancer foci were (38 cribriform, 20 non-cribriform foci) identified on the final pathology. mpMRI identified 36 of the 38 cribriform morphology harboring tumor foci with a sensitivity of 94.7% (95% confidence interval 82.7-98.5%). In 17 of the 33 patients mpMRI detected single lesion and for these lesions; mpMRI identified cribriform morphology positive areas precisely in 15 patients with significantly low ADCmean and ADCmin values compared to the non-cribriform cancer areas within the primary index lesion (P < .001). For the remaining 16 patients with multiple lesions; all of the tumor foci that harboring cribriform morphology were identified by mpMRI but in none of them any ADCmean and ADCmin value divergence were detected between the cribriform and non-cribriform pattern tumor foci within the primary index lesion. CONCLUSION: Cribiform pattern should be considered in single lesions with an area of lower ADC value on mpMRI.


Adenocarcinoma , Multiparametric Magnetic Resonance Imaging , Prostatic Neoplasms , Male , Humans , Prostate/diagnostic imaging , Prostate/pathology , Retrospective Studies , Prostatic Neoplasms/pathology , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/pathology , Magnetic Resonance Imaging , Prostatectomy
10.
Acad Radiol ; 29(5): 698-704, 2022 05.
Article En | MEDLINE | ID: mdl-32768351

PURPOSE: Our research aims to compare the efficacy of PET and MRI for lymph node metastasis and extraprostatic extension in cases with newly diagnosed prostate cancer undergoing radical prostatectomy with extended pelvic lymph node dissection. METHODS: Thirty-nine cases who underwent radical prostatectomy with pelvic lymph node dissection between June 2015 and January 2020 were included in the study. Patients with gallium (ga-68 Prostate-specific membrane antigen (PSMA) PET) PSMA PET-CT and multiparametric (mp) prostate MRI performed according to PIRADS v2 criteria in our clinic were included. RESULTS: The extraprostatic extension was observed in 16 cases. The sensitivity of MR in detecting extracapsular invasion was calculated as 56.2%, specificity 82.6%, positive predictive value (PPV) 69.2%, negative predictive value (NPV) 73.0%. The sensitivity of PET was 62.5%, specificity 60.8%, PPV 52.6%, NPV 70%. Eleven lymph node metastases were observed in nine cases. The sensitivity, specificity, PPV and NPV of metastatic lymph node detection were; 36.3%, 99.6%, 57.1%, 99.0% for MRI and; 18.1%, 99.4%, 33.3%, 98.8% for PET CT, respectively. CONCLUSION: Mp prostate MRI showed low sensitivity and high specificity compared to PSMA PET CT in extracapsular invasion evaluation. The sensitivity of both modalities in the detection of metastatic lymph nodes was low.


Gallium Radioisotopes , Prostatic Neoplasms , Gallium Isotopes , Humans , Lymph Nodes/diagnostic imaging , Lymph Nodes/pathology , Magnetic Resonance Imaging , Male , Positron Emission Tomography Computed Tomography , Prostate/pathology , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology , Prostatic Neoplasms/surgery
11.
Curr Med Imaging ; 18(4): 432-435, 2022.
Article En | MEDLINE | ID: mdl-34530716

BACKGROUND: Orbital metastasis of breast cancer is an unusual condition, especially in the absence of a previous diagnosis of primary breast cancer. The main MRI findings in patients with orbital metastasis are retroorbital soft tissue with thickening of extraocular muscles. Paradoxical enophthalmos secondary to fibrosis can be seen. CASE REPORT: In this case report, we present a 75-year-old female patient with left eye pain and blurred vision and retraction. Although there was no evidence of malignancy in the biopsy of the orbita; since the patient's complaints continued despite idiopathic pseudotumor treatment, mammography was recommended to rule out the possibility of breast cancer metastasis. Her mammography revealed a suspicious lesion in the left breast and proved to be pleomorphic invasive lobular cancer. CONCLUSION: Breast cancer metastasis should be kept in mind in women with pseudotumor -like the involvement of the orbita.


Breast Neoplasms , Carcinoma, Lobular , Orbital Neoplasms , Aged , Breast Neoplasms/diagnostic imaging , Breast Neoplasms/pathology , Carcinoma, Lobular/diagnostic imaging , Carcinoma, Lobular/secondary , Female , Humans , Magnetic Resonance Imaging , Mammography , Orbital Neoplasms/diagnostic imaging , Orbital Neoplasms/secondary
12.
Curr Med Imaging ; 18(1): 99-102, 2022.
Article En | MEDLINE | ID: mdl-34342259

INTRODUCTION: True thymic hyperplasia following chemotherapy has been described mostly in children. There are a few cases of thymus hyperplasia that have been reported in breast cancer patients. Diagnosis of this unusual entity is very crucial to pretend unnecessary surgery or interventional diagnostic procedures. CASE PRESENTATION: We report a case of thymus hyperplasia in a patient who was operated and treated with adjuvant chemotherapy for stage 2 breast cancer two years ago. In the follow-up CT scans, an anterior mediastinal mass was noted. Radiologic evaluation and follow-up revealed thymus enlargement. DISCUSSION: Thymic hyperplasia following chemotherapy has been described in both children and adults, but occurs mostly in children and adolescents treated for lymphoma and several other types of tumors. Few cases are reported in literature describing thymus hyperplasia following chemotherapy in a breast cancer patient. The imaging findings of thymic hyperplasia on CT, MRI and PET CT are discussed. CONCLUSION: Radiologists must be aware of this unusual finding in breast cancer patients treated with chemotherapy to guide the clinicians appropriately in order to avoid unnecessary surgical intervention, additional invasive diagnostic procedures, or chemotherapy.


Breast Neoplasms , Thymus Hyperplasia , Adolescent , Adult , Breast Neoplasms/diagnostic imaging , Child , Female , Humans , Positron Emission Tomography Computed Tomography , Thymus Hyperplasia/diagnostic imaging , Thymus Hyperplasia/pathology , Tomography, X-Ray Computed
13.
Acad Radiol ; 29(8): 1143-1148, 2022 08.
Article En | MEDLINE | ID: mdl-34955365

RATIONALE AND OBJECTIVE: We aimed to compare the diagnostic performance of an automated breast ultrasound system (ABUS) with handheld ultrasound (HHUS) in the detection and characterization of lesions regarding BI-RADS classification in women with dense breasts. MATERIALS AND METHODS: After ethical approval, from July 2017 to August 2019, 592 consecutive patients were enrolled in this prospective study. On the same day, patients underwent ABUS followed by HHUS. Three breast radiologists participated in this study. The number and type of lesions and BI-RADS categorization of both ABUS and HHUS examinations of each patient were recorded in an excel file. The level of agreement between the two ultrasound systems in terms of lesion number and BI-RADS category were analyzed statistically. RESULTS: ABUS and HHUS detected 1005 and 1491 cystic and 270 and 336 mass lesions in 592 patients respectively. ABUS and HHUS detected 171 and 167 positive/suspicious cases (BIRADS 0/3/4/5). Forty suspicious lesions underwent core needle biopsy whereas 11 malignant lesions were detected by both methods. The remaining lesions were followed with a mean of 31 months. The mean size of solid lesions detected by HHUS and ABUS was 7.67 mm (range 2.1-41 mm) and 7.74 mm (range 2-42 mm) respectively. The agreement for detection of cystic lesions between two methods for each breast was good (kappa: 0.61-0.62 p < 0.001). The agreement of two methods for solid mass lesions for each breast was moderate (k = 0.57-0.60 p < 0.001). There was good agreement between the two methods for detecting suspicious lesions (kappa = 0.66 p < 0.001). CONCLUSION: The level of agreement of ABUS and HHUS for dichotomic assignment of BIRADS categories was good. Although ABUS detected fewer lesions compared to HHUS, both methods detected all malignant lesions. ABUS is a reliable method for the detection of malignancy in dense breasts.


Breast Density , Breast Neoplasms , Breast Neoplasms/diagnostic imaging , Female , Humans , Mammography/methods , Prospective Studies , Sensitivity and Specificity , Ultrasonography, Mammary/methods
14.
J Med Imaging Radiat Sci ; 52(3): 374-378, 2021 09.
Article En | MEDLINE | ID: mdl-34183303

OBJECTIVE: In this study we aimed to evaluate the operation times of ABUS by technologists during the learning time course and share the learning experience. MATERIALS AND METHOD: The first consequent 400 examinations after the installation of an ABUS unit in the breast clinic between August 2017 and December 2017 were included. Total examination time was measured for each procedure. The initial and final examination times during the learning period were compared. Data were analyzed with the Mann-Whitney Test. RESULTS: The acquisition times for routine six position examination ranged between eight and 36 minutes with an average of 13.2 ± 3.58 min. The examination time for the eight position examination ranged between 18 and 32 min, with an average of 22.9 ± 3.93 min. The overall average examination time was 13.3 ± 3.98 min. There was a significant difference (p = 0.00) between the average initial and final examination times of the learning period with an average decrease of 10.6 min. CONCLUSION: The average time of an ABUS examination for an average breast is less than 15 min. ABUS examination time reduced as technologists became familiar with the sonographic anatomy of the breast and experienced in positioning technique during the learning curve.


Breast , Ultrasonography, Mammary , Breast/diagnostic imaging , Breast Density , Female , Humans , Ultrasonography
15.
Eur J Radiol ; 141: 109791, 2021 Aug.
Article En | MEDLINE | ID: mdl-34062471

PURPOSE: To investigate whether prostate cancer (PCa) lesions regarding histopathological composition exhibit different morphological features on multiparametric prostate MRI (mpMRI). METHODS: We investigated men with PCa with available mpMRI and whole-mount specimens between June 2015 to December 2020.The acquisition protocol consistent with the Prostate Imaging Reporting and Data System (PI-RADS). Two observers evaluated the images following the PI-RADS v2.1. guideline before biopsy and radical prostatectomy. The discrepancies were resolved in a joint meeting. A genitourinary pathologist reviewed the whole-digitalized mount specimens, and the lesions with Gleason score of 7 and above (3 + 4 and above), and/or cancers with a maximum diameter of 6 mm and more, and/or extraprostatic extension were accepted as clinically significant PCa. The PI-RADS scores and the diameter of the clinically significant PCa on mpMRI concerning histopathological components (i.e., cribriform component, intraductal pattern, or without cribriform component or intraductal pattern) were investigated. The clinically significant PCa foci with PI-RADS score <3 was accepted as an invisible lesion on mpMRI. RESULTS: In all, 58 men with a total of 112 clinically significant PCa foci, were enrolled in the study. The intraductal pattern, cribriform pattern, or none of these patterns were observed in 28/112 (25 %), 43/112 (38.05 %), and 41/112 (36.60 %) tumor foci. Six out of 28 (21.42 %), 17/43 (39.53 %), and 18/41 (42.8 %) foci with an intraductal pattern, cribriform component, or without any of them, respectively, were invisible on mpMRI (P = 0.111). CONCLUSION: Though it was not reached a statistical significance, clinically significant PCa with the cribriform component and without any intraductal or cribriform component are more likely to manifests mpMRI invisible foci than the intraductal pattern. Further multi-center studies are warranted to precisely elucidate mpMRI features of PCa regarding histopathological composition.


Multiparametric Magnetic Resonance Imaging , Prostatic Neoplasms , Humans , Magnetic Resonance Imaging , Male , Neoplasm Grading , Prostatectomy , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/surgery , Retrospective Studies
16.
J Comput Assist Tomogr ; 45(2): 210-217, 2021.
Article En | MEDLINE | ID: mdl-33186177

PURPOSE: The aim of our study is to compare the efficacy of positron emission tomography (PET) and magnetic resonance imaging (MRI) for detecting intraprostatic lesions in patients with clinically significant prostate cancer who underwent radical prostatectomy; additionally, investigate the benefits of rostate-specific membrane antigen (PSMA) PET-MR software fusion images to the diagnosis. METHODS: Thirty patients, who underwent radical prostatectomy between June 2015 and April 2018, were included in the study. Subjects with gallium PSMA PET-CT and multiparametric prostate MRI performed according to Prostate Imaging Reporting and Data System v2 criteria in our clinic were included in the study. 68Ga-PSMA PET-CT images were fused with MR sequences for analysis. RESULTS: The mean age of cases was 63.2 years (ranged from 45 to 79 years). Index lesions of 29 cases were detected by MRI and 22 of them by PET CT. Both modalities were found to be less sensitive for detection of bilaterality and multifocality (42.85% and 20% for MRI, 28.57% and 20% for PET CT, respectively). There was no statistically significant difference between modalities. It was observed that if a clinically significant tumor focus was not detected by MRI, it was small (6 mm or less) in diameter or had a low Gleason score. CONCLUSIONS: Software fusion PSMA PET-MRI increased the sensitivity of the index lesion identification compared with PSMA PET-CT and also increased the sensitivity of real lesion size identification compared with multiparametric prostate MRI.


Image Interpretation, Computer-Assisted , Magnetic Resonance Imaging , Positron Emission Tomography Computed Tomography , Prostate , Prostatic Neoplasms , Aged , Humans , Male , Middle Aged , Prostate/diagnostic imaging , Prostate/pathology , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology , Retrospective Studies
17.
Clin Neuroradiol ; 30(1): 145-157, 2020 Mar.
Article En | MEDLINE | ID: mdl-30470848

PURPOSE: Acute neck pain can have non-vascular and vascular causes. Some patients present with distinct vascular and perivascular changes on imaging at the site of tenderness. This study aimed to evaluate the imaging findings of transient perivascular inflammation of the carotid artery (TIPIC) syndrome with an emphasis on vessel wall imaging using 3­Tesla (3-T) high-resolution (HR) magnetic resonance imaging (MRI). METHODS: Clinical data along with diagnostic and follow-up imaging of patients presenting to these hospitals with acute neck pain/tenderness and at least 1 imaging study using color Doppler ultrasound (CDU) and/or MRI including vessel wall imaging from September 2013 through September 2017 were retrospectively evaluated. A total of 15 patients with no other underlying cause of pain, findings meeting the imaging criteria for TIPIC syndrome and clinical recovery (spontaneous or with treatment) were included in the study. RESULTS: The mean patient age was 43.2 years. With CDU and precontrast MRI, perivascular inflammation (PVI) of the involved artery segment was evident in all patients. Contrast enhancement of the adventitia and PVI were noted on postcontrast HR vessel wall MRI in all patients. Of the patients five had co-existing plaques at the site of tenderness. Follow-up imaging demonstrated pronounced regression or complete resolution of the findings. CONCLUSION: Imaging is useful for the establishment of TIPIC syndrome diagnosis and to rule out other conditions. The use of CDU is usually sufficient for diagnosis and follow-up but in clinically doubtful and complicated cases, vessel wall imaging with HR-MRI is very valuable. Thorough knowledge of this entity among radiologists enables a prompt diagnosis, which accelerates the clinical management.


Carotid Artery Diseases/diagnostic imaging , Inflammation/diagnostic imaging , Magnetic Resonance Imaging/methods , Adult , Carotid Arteries/diagnostic imaging , Carotid Artery Diseases/complications , Female , Humans , Inflammation/complications , Male , Middle Aged , Neck Pain/etiology , Reproducibility of Results , Retrospective Studies , Syndrome
19.
Childs Nerv Syst ; 36(7): 1415-1423, 2020 07.
Article En | MEDLINE | ID: mdl-31865402

PURPOSE: The goal of this study was to determine stoma and flow patency with 3D SPACE T2 and 3D CISS sequences in cases with cystocisternostomy or cystoventriculostomy. METHODS: A total of sixty three patients (total 106 MRI examinations) with endoscopic cystocisternostomy or cystoventriculostomy of arachnoid cyst underwent 1.5-3 T MRI to determine flow patency between June 2007 and April 2018. Postoperative results, the patients' clinic and arachnoid cyst volume were used to confirm stoma and flow patency in MRI. RESULTS: The stoma was open and functional in forty three patients. Minimal flow was detected in five patients. Fifteen patients with closed stoma (total 17 MR images) were evaluated with the clinician. Patients' clinic, physical examination, and growth (for pediatric patients) were evaluated. Three of fifteen patients were re-operated. Operative findings and postoperative follow-up MR imaging findings were correlated with our preoperative MRI results. The findings were in compliance in both groups (operated-non-operated groups). CONCLUSION: 3D SPACE T2 and 3D CISS are effective sequences in addition to other routine conventional sequences to evaluate stoma and flow patency.


Arachnoid Cysts , Arachnoid Cysts/diagnostic imaging , Arachnoid Cysts/surgery , Child , Endoscopy , Humans , Magnetic Resonance Imaging , Postoperative Period
20.
Eur J Breast Health ; 15(4): 207-212, 2019 Oct.
Article En | MEDLINE | ID: mdl-31620677

OBJECTIVE: We aimed to evaluate the mammography experience of patients using a manually controlled self- compression tool compared to their previous experience based on technician performed breast compression by a questionnaire survey study. MATERIALS AND METHODS: The survey studies of 365 patients who underwent screening or diagnostic mammography between April 2017 and July 2017 at our center were reviewed retrospectively. Each patient had completed a 12-item questionnaire following mammography examinations. Women who never had a mammography before or who had a previous mammography examination more than 2 years ago or who did not want to use the self-compression device were excluded from the study. 106 women were included in the study. RESULTS: Patient satisfaction was high. Regarding the comparison of the experience of the exam to previous ones, 70.8% said it was a better experience. The examination was found comfortable by 85.4% of the participants and 75.5% found the examination more comfortable compared to previous ones. Only 11.3% were anxious and 52.8% declared they were less anxious compared to previous examinations. Regarding the attractiveness of the new design, 66.9% declared they found the new design attractive, 39.7% found it more attractive than previous examinations, and 27.3% said the new design decreased anxiety. In the evaluation of impact of patient-assisted compression (PAC) on comfort, 80.2% said that they found it more comfortable and 64.2% said that PAC decreased anxiety. Furthermore, 72.6% said the exam was shorter. CONCLUSION: Self-compression technique decreases pain and anxiety of women during mammography examinations and promises to enhance compliance of clients and patients with follow-up mammography recommendations.

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