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1.
Cardiovasc Intervent Radiol ; 44(7): 1121-1126, 2021 Jul.
Article En | MEDLINE | ID: mdl-33851264

PURPOSE: Patients undergoing long-term hemodialysis may suffer upper extremity central venous access failure and require an alternative route. This study aimed to evaluate the safety and efficacy of transrenal hemodialysis catheter insertion/replacement in patients with upper extremity central venous access failure. MATERIALS AND METHODS: A multicenter retrospective cohort study was made of transrenal hemodialysis catheter insertion/replacement performed between 2014 and 2020. The history of renal replacement therapy and central venous catheters and the technical details of transrenal hemodialysis catheter insertion/replacement, patency, removal and complications were obtained for all patients. RESULTS: Six insertion and four replacement procedures involving transrenal hemodialysis catheters were evaluated in six patients (M:F = 3:3; median age, 49.5 years). Percutaneous transrenal (right:left = 1:5) hemodialysis catheter insertion was technically successful without complication in all six patients. In two patients, the tract was not lost because the safety guidewire was still in place, so no second puncture was required. The mean procedure time was 33.0 ± 9.2 min. The mean primary patency duration was 107.3 ± 70.9 days. During the mean follow-up duration of 141.2 ± 137.1 days, four hemodialysis catheter replacement procedures were successfully performed for catheter malfunction (n = 2) and dislodgement (n = 2). Catheter removal was successfully performed in four patients after confirming normal coagulation, followed by subsequent renal replacement therapy. CONCLUSION: Percutaneous insertion/replacement of transrenal hemodialysis catheters is feasible, safe, and effective when upper extremity central venous access is exhausted, and the catheters can be maintained for a reasonable period of time. LEVEL OF EVIDENCE: Level 4, Case Series.


Catheterization, Central Venous/methods , Central Venous Catheters , Renal Dialysis/methods , Adult , Aged , Aged, 80 and over , Device Removal , Female , Humans , Kidney Failure, Chronic/therapy , Male , Middle Aged , Retrospective Studies , Upper Extremity , Veins , Young Adult
2.
Vasc Specialist Int ; 32(3): 77-104, 2016 Sep.
Article En | MEDLINE | ID: mdl-27699156

Lower extremity deep vein thrombosis is a serious medical condition that can result in death or major disability due to pulmonary embolism or post-thrombotic syndrome. Appropriate diagnosis and treatment are required to improve symptoms and salvage the affected limb. Early thrombus clearance rapidly resolves symptoms related to venous obstruction, restores valve function and reduces the incidence of post-thrombotic syndrome. Recently, endovascular treatment has been established as a standard method for early thrombus removal. However, there are a variety of views regarding the indications and procedures among medical institutions and operators. Therefore, we intend to provide evidence-based guidelines for diagnosis and treatment of lower extremity deep vein thrombosis by multidisciplinary consensus. These guidelines are the result of a close collaboration between interventional radiologists and vascular surgeons. The goals of these guidelines are to improve treatment, to serve as a guide to the clinician, and consequently to contribute to public health care.

3.
Korean J Radiol ; 16(4): 696-722, 2015.
Article En | MEDLINE | ID: mdl-26175569

Peripheral arterial occlusive disease caused by atherosclerosis can present with intermittent claudication or critical limb ischemia. Proper diagnosis and management is warranted to improve symptoms and salvage limbs. With the introduction of new techniques and dedicated materials, endovascular recanalization is widely performed for the treatment of peripheral arterial occlusive disease because it is less invasive than surgery. However, there are various opinions regarding the appropriate indications and procedure methods for interventional recanalization according to operator and institution in Korea. Therefore, we intend to provide evidence based guidelines for interventional recanalization by multidisciplinary consensus. These guidelines are the result of a close collaboration between physicians from many different areas of expertise including interventional radiology, interventional cardiology, and vascular surgery. The goal of these guidelines is to ensure better treatment, to serve as a guide to the clinician, and consequently, to contribute to public health care.


Arterial Occlusive Diseases/therapy , Endovascular Procedures/standards , Lower Extremity/blood supply , Peripheral Arterial Disease/therapy , Practice Guidelines as Topic , Arterial Occlusive Diseases/diagnostic imaging , Arteries/pathology , Humans , Intermittent Claudication/diagnostic imaging , Intermittent Claudication/therapy , Limb Salvage/methods , Peripheral Arterial Disease/diagnostic imaging , Radiography , Republic of Korea
4.
Cytokine ; 76(2): 449-457, 2015 Dec.
Article En | MEDLINE | ID: mdl-26163999

We investigated the association between serum interleukin (IL)-8 levels and post-transarterial chemoembolization (TACE) outcomes in patients with hepatitis B virus (HBV)-associated HCC. We enrolled 119 TACE-treated patients with HBV-associated HCC; TACE refractoriness and liver transplantation (LT)-free survival were evaluated during follow-up. Pre-TACE serum levels of various cytokines (epidermal growth factor [EGF], fibroblast growth factor 2, granulocyte-colony stimulating factor [G-CSF], interferon-γ, IL-8, IL-12, IL-17A, interferon-γ-inducible protein-10, monocyte chemotactic protein-1, tumor necrosis factor-α and vascular endothelial growth factor) were analyzed. During a mean follow-up of 24.3 (1-79) months, 91 patients (76.5%) exhibited TACE refractoriness. In multivariate analyses, multiple tumors (hazard ratio [HR], 2.37; 95% confidence interval [CI], 1.28-4.39; P=0.006), large tumor size (HR, 2.36; 95% CI, 1.38-4.03; P=0.002), and combination of alpha-fetoprotein and IL-8 levels (AFP>400 ng/mL or IL-8>32 pg/mL; HR, 1.72; 95% CI, 1.03-2.85; P=0.037) independently predicted overall TACE refractoriness. Higher EGF (>35 pg/mL) and lower G-CSF levels (⩽ 12.5 pg/mL) were associated with early TACE refractoriness (<1 year; HR, 3.47; 95% CI, 1.01-11.96; P=0.049 and HR, 6.25; 95% CI, 1.62-23.81; P=0.008, respectively). Furthermore, high IL-8 level (>32 pg/mL; HR, 1.68; 95% CI, 1.09-2.59; P=0.020) was associated with poor LT-free survival. In conclusion, pretreatment serum IL-8 is a useful prognostic marker for TACE refractoriness and LT-free survival in TACE-treated patients with HBV-associated HCC.


Biomarkers, Tumor/blood , Carcinoma, Hepatocellular/therapy , Chemoembolization, Therapeutic , Hepatitis B virus/pathogenicity , Interleukin-8/blood , Liver Neoplasms/therapy , Aged , Carcinoma, Hepatocellular/blood , Carcinoma, Hepatocellular/virology , Female , Humans , Liver Neoplasms/blood , Liver Neoplasms/virology , Male , Middle Aged , Prognosis , Retrospective Studies , Survival Analysis
5.
Semin Dial ; 27(1): 61-7, 2014.
Article En | MEDLINE | ID: mdl-24028825

To examine the relationship between intra-access pressures and vascular stenosis, we measured the total (pT ) and static (pS ) pressures and the severity of stenosis before and after percutaneous transluminal angioplasty (PTA). The dynamic pressure (△p) and static intra-access pressure ratios (SIAPR) were calculated. We analyzed the clinical correlation of △p and SIAPR with the severity and location of stenosis, and searched potential predictive factors for the severity of stenosis using multivariate regression. While SIAPR was significantly decreased only in outflow stenosis after PTA (p < 0.0001), △p was significantly increased in both inflow and in outflow stenosis (p < 0.05). SIAPR was negatively correlated with the severity of stenosis only in outflow stenosis (p < 0.0001), and △p was significantly correlated with both inflow and outflow stenosis (p < 0.05). △p was an independent predictor for the severity of stenosis in both inflow and outflow stenosis (p < 0.05). Thus, our study suggests that △p may be more clinically useful than SIAPR not only in detecting access stenosis regardless of its location, but also providing information about the severity of stenosis.


Arteriovenous Shunt, Surgical/adverse effects , Blood Pressure/physiology , Graft Occlusion, Vascular/diagnosis , Angioplasty , Blood Flow Velocity/physiology , Female , Graft Occlusion, Vascular/physiopathology , Graft Occlusion, Vascular/therapy , Humans , Kidney Failure, Chronic/physiopathology , Male , Middle Aged , Multivariate Analysis , Severity of Illness Index , Ultrasonography, Interventional
6.
AJR Am J Roentgenol ; 201(5): W707-11, 2013 Nov.
Article En | MEDLINE | ID: mdl-24147500

OBJECTIVE: The purpose of this study was to validate the usefulness of MDCT for diagnosis of a sharp or pointed esophageal foreign body according to esophageal level. MATERIALS AND METHODS: Forty-two patients with a history of sharp or pointed foreign body ingestion were reviewed retrospectively. Two observers interpreted the CT and the conventional radiography datasets separately. If a foreign body was directly identified, it was regarded as a positive finding. Even if no high-density foreign body was found, detection of a secondary finding was considered to be a positive finding. Diagnostic performance of MDCT and conventional radiography were compared according to esophageal level. Final diagnosis was made by esophagoscopy or surgery in addition to the clinicoradiologic result. RESULTS: MDCT was statistically superior to conventional radiography for diagnosis of a thoracic esophageal foreign body for both observers (p < 0.001 for each). No significant difference in sensitivity between CT and conventional radiography for diagnosis of cervical esophageal foreign body was noted regardless of observer. Both observers could identify all complicated conditions with MDCT regardless of esophageal level. However, in two of three cases of complicated thoracic esophageal foreign bodies, neither observer could detect foreign bodies on conventional radiography; furthermore, the observers could not identify pneumomediastinum. CONCLUSION: In cases of sharp or pointed foreign body ingestion, if the result of an initial inspection of oro- and hypopharynx reveals negative findings, the first imaging modality should be MDCT for better diagnosis and management.


Esophagus/diagnostic imaging , Foreign Bodies/diagnostic imaging , Multidetector Computed Tomography/methods , Contrast Media , Female , Foreign Bodies/therapy , Humans , Iohexol/analogs & derivatives , Male , Middle Aged , Retrospective Studies
7.
Korean J Radiol ; 14(3): 430-8, 2013.
Article En | MEDLINE | ID: mdl-23690709

OBJECTIVE: To evaluate the impact on wound healing and long-term clinical outcomes of endovascular revascularization in patients with critical limb ischemia (CLI). MATERIALS AND METHODS: This is a retrospective study on 189 limbs with CLI treated with endovascular revascularization between 2008 and 2010 and followed for a mean 21 months. Angiographic outcome was graded to technical success (TS), partial failure (PF) and complete technical failure. The impact on wound healing of revascularization was assessed with univariate analysis and multivariate logistic regression models. Analysis of long-term event-free limb survival, and limb salvage rate (LSR) was performed by Kaplan-Meier method. RESULTS: TS was achieved in 89% of treated limbs, whereas PF and CF were achieved in 9% and 2% of the limbs, respectively. Major complications occurred in 6% of treated limbs. The 30-day mortality was 2%. Wound healing was successful in 85% and failed in 15%. Impact of angiographic outcome on wound healing was statistically significant. The event-free limb survival was 79.3% and 69.5% at 1- and 3-years, respectively. The LSR was 94.8% and 92.0% at 1- and 3-years, respectively. CONCLUSION: Endovascular revascularization improve wound healing rate and provide good long-term LSRs in CLI.


Endovascular Procedures/methods , Foot/blood supply , Ischemia/surgery , Wound Healing/physiology , Adult , Aged , Aged, 80 and over , Analysis of Variance , Endovascular Procedures/adverse effects , Female , Humans , Ischemia/physiopathology , Limb Salvage , Male , Middle Aged , Retrospective Studies , Risk Factors , Survival Rate , Treatment Outcome
8.
Eur Radiol ; 23(3): 780-5, 2013 Mar.
Article En | MEDLINE | ID: mdl-22983316

OBJECTIVES: To evaluate the technical feasibility and clinical effectiveness of retrievable self-expandable metallic stents with barbs in patients with obstructive prostate cancer. METHODS: Retrievable self-expandable metallic stents with eight barbs each were inserted into eight consecutive patients with obstructive prostate cancer. Patient ages ranged from 55 to 76 years (mean, 69 years). All eight patients had previously received hormone therapy, and three had undergone palliative transurethral prostatectomy. Stents were removed using a 21-F stent removal set if they caused complications. RESULTS: Stent placement was technically successful and well tolerated in all patients. One had severe incontinence, which improved spontaneously, and two had gross haematuria, which disappeared spontaneously within 4 days. Peak urine flow rates and post-void residual urine volumes 1 month after stent placement were 5.6-10.2 ml/s (mean, 8.3 ml/s), and 5-45 ml (mean, 27 ml), respectively. During a mean follow-up of 192 days (range, 39-632 days), one patient required stent removal after 232 days because of stone formation within the stent. No further intervention was required because the mass improved after stent removal. CONCLUSIONS: These preliminary results suggest that retrievable stents with eight barbs are both feasible to place and effective in patients with obstructive prostate cancer.


Device Removal/methods , Metals , Prostatic Neoplasms/surgery , Stents , Ureteral Obstruction/surgery , Aged , Equipment Design , Equipment Failure Analysis , Feasibility Studies , Humans , Male , Middle Aged , Prostatic Neoplasms/complications , Prostatic Neoplasms/diagnostic imaging , Radiography , Treatment Outcome , Ureteral Obstruction/diagnostic imaging , Ureteral Obstruction/etiology
9.
Korean J Radiol ; 13(6): 795-802, 2012.
Article En | MEDLINE | ID: mdl-23118579

OBJECTIVE: To evaluate the feasibility, safety and the effectiveness of the complex assembly of open cell nitinol stents for biliary hilar malignancy. MATERIALS AND METHODS: During the 10 month period between January and October 2007, 26 consecutive patients with malignant biliary hilar obstruction underwent percutaneous insertion of open cell design nitinol stents. Four types of stent placement methods were used according to the patients' ductal anatomy of the hilum. We evaluated the technical feasibility of stent placement, complications, patient survival, and the duration of stent patency. RESULTS: Bilobar biliary stent placement was conducted in 26 patients with malignant biliary obstruction-T (n = 9), Y (n = 7), crisscross (n = 6) and multiple intersecting types (n = 4). Primary technical success was obtained in 24 of 26 (93%) patients. The crushing of the 1st stent during insertion of the 2nd stent occurred in two cases. Major complications occurred in 2 of 26 patients (7.7%). One case of active bleeding from hepatic segmental artery and one case of sepsis after procedure occurred. Clinical success was achieved in 21 of 24 (87.5%) patients, who were followed for a mean of 141.5 days (range 25-354 days). The mean primary stent patency period was 191.8 days and the mean patient survival period was 299 days. CONCLUSION: Applying an open cell stent in the biliary system is feasible, and can be effective, especially in multiple intersecting stent insertions in the hepatic hilum.


Alloys , Bile Duct Neoplasms/complications , Cholangiocarcinoma/complications , Cholestasis, Intrahepatic/therapy , Drainage/instrumentation , Palliative Care , Stents , Adult , Aged , Aged, 80 and over , Cholestasis, Intrahepatic/etiology , Female , Gallbladder Neoplasms/complications , Humans , Male , Middle Aged
10.
AJR Am J Roentgenol ; 198(5): 1203-7, 2012 May.
Article En | MEDLINE | ID: mdl-22528914

OBJECTIVE: The objective of our study was to assess the technical feasibility and clinical effectiveness of expandable metallic stent placement in patients with nonanastomotic malignant jejunal obstruction after total gastrectomy with esophagojejunostomy. MATERIALS AND METHODS: We retrospectively analyzed data from 21 patients with malignant jejunal obstruction after total gastrectomy with esophagojejunostomy who received one of two types of expandable metallic stent. Clinical effectiveness was assessed using the following variables: technical and clinical outcomes, complications, dysphagia scores before and after stent placement, patient survival, and stent patency. Complications with related interventions were evaluated and compared between the two stent types. RESULTS: Stent placement was technically successful in 20 of the 21 patients (95%) with 19 of 20 patients (95%) showing symptomatic improvement. Type A stents were used in 10 patients and type B stents in the remaining 10 patients. Complications occurred with seven of 20 stents (35%) and involved stent migration (n = 3), tumor overgrowth (n = 3), or pain (n = 1). The dysphagia score before stent placement (mean ± SD, 3.2 ± 0.5) had improved by 3 days after stent placement (1.3 ± 0.9, p < 0.001) and was maintained compared with the initial score up to 1 month (1.7 ± 1.1, p < 0.001) and 3 months (2.1 ± 1.5, p = 0.021) after stent placement. The median patient survival and stent patency were 114 and 46 days, respectively. The type of stent was not significantly related to complications (p = 0.350). CONCLUSION: Placement of expandable metallic stents to treat nonanastomotic malignant jejunal obstruction in patients who have undergone total gastrectomy with esophagojejunostomy is feasible and clinically effective.


Gastric Outlet Obstruction/etiology , Gastric Outlet Obstruction/surgery , Stents , Stomach Neoplasms/surgery , Adult , Aged , Contrast Media , Disease Progression , Esophagostomy , Female , Fluoroscopy , Gastrectomy , Gastric Outlet Obstruction/pathology , Humans , Jejunostomy , Male , Metals , Middle Aged , Neoplasm Recurrence, Local , Palliative Care , Postoperative Complications/epidemiology , Prosthesis Design , Retrospective Studies , Stents/adverse effects , Stomach Neoplasms/pathology , Survival Rate , Treatment Outcome
11.
Korean J Radiol ; 13(2): 117-25, 2012.
Article En | MEDLINE | ID: mdl-22438678

Thermal ablation using radiofrequency is a new, minimally invasive modality employed as an alternative to surgery in patients with benign thyroid nodules and recurrent thyroid cancers. The Task Force Committee of the Korean Society of Thyroid Radiology has developed recommendations for the optimal use of radiofrequency ablation for thyroid nodules. These recommendations are based on a comprehensive analysis of the current literature, the results of multicenter studies, and expert consensus.


Catheter Ablation/methods , Thyroid Neoplasms/surgery , Thyroid Nodule/surgery , Biopsy, Fine-Needle , Consensus , Humans , Informed Consent , Neoplasm Recurrence, Local/parasitology , Neoplasm Recurrence, Local/surgery , Patient Safety , Radio Waves , Republic of Korea , Thyroid Neoplasms/pathology , Thyroid Nodule/pathology , Ultrasonography, Interventional
12.
AJR Am J Roentgenol ; 198(2): 460-5, 2012 Feb.
Article En | MEDLINE | ID: mdl-22268194

OBJECTIVE: The objective of our study was to evaluate the efficacy and safety of a venotomy and manual propulsion technique that is performed to treat failed native arteriovenous fistulas (AVFs) with chronic organized thrombi. MATERIALS AND METHODS: For this study, we retrospectively reviewed a total of 69 venotomy and manual propulsion procedures performed from October 2005 to July 2009 in 56 patients for the treatment of native AVFs occluded by chronic thrombi. Inflow, anastomotic, and outflow veins were occluded using balloon catheters. Venotomy was made in the thrombi-bearing vein, and thrombi were propelled toward the venotomy site in a "milking" manner and were removed. After repair of the venotomy using simple interrupted sutures, the occlusion balloons were deflated. Angioplasty of the underlying stenosis was performed. RESULTS: Technical success was achieved in 95.7% of the procedures and clinical success was achieved in 91.3%. The follow-up duration was 1-50 months (mean, 16.7 months), with 3-, 6-, and 12-month primary patency rates of 92.5%, 80.8%, and 58.1%, respectively, and secondary patency rates of 98.1%, 96.2%, and 91.7%. The complication rate was 7.24%, with two major and three minor complications. CONCLUSION: The venotomy and manual propulsion technique is effective and safe for the removal of chronic and organized thrombi from occluded native AVFs.


Arteriovenous Shunt, Surgical/adverse effects , Graft Occlusion, Vascular/etiology , Graft Occlusion, Vascular/therapy , Thrombectomy/methods , Thrombosis/complications , Thrombosis/therapy , Adult , Aged , Aged, 80 and over , Angioplasty , Female , Humans , Male , Middle Aged , Renal Dialysis , Retrospective Studies , Treatment Outcome , Vascular Patency
13.
Radiology ; 262(1): 335-42, 2012 Jan.
Article En | MEDLINE | ID: mdl-21998044

PURPOSE: To evaluate clinical aspects and imaging features of complications encountered in the treatment of benign thyroid nodules with radiofrequency (RF) ablation. MATERIALS AND METHODS: Institutional review board approval was obtained for this retrospective study, and informed consent was waived. From June 2002 to September 2009, 1459 patients underwent RF ablation of 1543 thyroid nodules with an RF system with internally cooled electrodes at 13 thyroid centers, which were members of Korean Society of Thyroid Radiology. Numbers and types of major and minor complications were assessed. RESULTS: The authors observed 48 complications (3.3%), 20 major and 28 minor. The major complications were voice changes (n = 15), brachial plexus injury (n = 1), tumor rupture (n = 3), and permanent hypothyroidism (n = 1). The minor complications were hematoma (n = 15), skin burn (n = 4), and vomiting (n = 9). All patients recovered spontaneously except for one with permanent hypothyroidism and one who underwent surgery. CONCLUSION: Although the complication rate of RF ablation is low, various complications may occur; comprehension of complications and suggested technical tips may prevent complications or properly manage those that occur.


Catheter Ablation/methods , Postoperative Complications/epidemiology , Thyroid Nodule/surgery , Ultrasonography, Interventional , Adult , Chi-Square Distribution , Female , Humans , Incidence , Male , Republic of Korea/epidemiology , Retrospective Studies , Surveys and Questionnaires , Thyroid Nodule/diagnostic imaging , Thyroid Nodule/pathology , Treatment Outcome
14.
J Vasc Interv Radiol ; 22(10): 1420-6, 2011 Oct.
Article En | MEDLINE | ID: mdl-21840225

PURPOSE: To report the use of a newly constructed, covered, retrievable, expandable nitinol stent with barbs to overcome the problem of stent migration associated with conventional covered prostatic expandable stents and to evaluate prospectively the technical feasibility and clinical effectiveness of the stents in patients with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A covered retrievable expandable nitinol stent with four barbs was placed with use of an 18-F stent delivery system in seven consecutive patients with symptomatic BPH who had high operative risks. Age range of patients was 62-83 years (mean 74 years). In cases in which the stent migrated, it was replaced with a stent with eight barbs. The stents were routinely removed 4 months after placement using a 21-F stent removal set. RESULTS: Stent placement was technically successful and well tolerated in six of the seven patients. The remaining patient needed a second stent placement after removal of the first stent. The stent with four barbs migrated into the urinary bladder in four patients (57%); three of these patients received a second stent with eight barbs with good results, and the fourth patient did not need further treatment because his symptoms improved. Routine removal of the stent 4 months after placement was performed in three of the seven patients with good results. CONCLUSIONS: Retrievable stents with eight barbs seem to overcome the problem of stent migration associated with conventional prostatic expandable stents. Preliminary results suggest that stents with barbs are both feasible and effective in patients with BPH.


Alloys , Catheterization/instrumentation , Prostatic Hyperplasia/therapy , Stents , Aged , Aged, 80 and over , Catheterization/adverse effects , Device Removal , Feasibility Studies , Foreign-Body Migration/etiology , Foreign-Body Migration/prevention & control , Humans , Male , Pilot Projects , Prospective Studies , Prostatic Hyperplasia/diagnostic imaging , Prosthesis Design , Radiography, Interventional , Republic of Korea , Stents/adverse effects , Time Factors , Treatment Outcome , Ureteroscopy
15.
Angiology ; 61(4): 392-6, 2010 May.
Article En | MEDLINE | ID: mdl-19759029

We evaluated 158 legs from 79 consecutive patients who had undergone both ankle-brachial index (ABI) measurements and angiography for claudication symptoms between January 2007 and December 2008. The diagnosis of peripheral arterial disease (PAD) in the individual legs was established by angiography. Ankle-brachial index was considered abnormal if it was <0.9. The sensitivity and specificity of ABI was 61% and 87%, respectively. To assess the factors affecting the validity of ABI in the diagnosis of PAD, multivariate logistic regression analysis was conducted. The odds ratios (ORs) for the false negative result of ABI were 4.36 (95% confidence interval [CI] 1.36-13.92) in patients with diabetes mellitus (DM), 3.41 (95% CI 1.10-10.48) in patients with distal lesions, 3.02 (95% CI 1.07-8.49) in elderly patients, and 1.13 (95% CI 0.34-3.42) in patients with mild stenosis. Although ABI is the method of choice for the primary diagnosis of PAD, other supplementary investigations should be considered when there is clinical suspicion of PAD but an ABI <0.9.


Ankle Brachial Index , Arterial Occlusive Diseases/diagnosis , Leg/blood supply , Peripheral Vascular Diseases/diagnosis , Aged , Arterial Occlusive Diseases/etiology , Arterial Occlusive Diseases/physiopathology , Cohort Studies , False Negative Reactions , Female , Humans , Logistic Models , Male , Middle Aged , Peripheral Vascular Diseases/etiology , Peripheral Vascular Diseases/physiopathology , Predictive Value of Tests , Reproducibility of Results , Retrospective Studies , Risk Factors
16.
J Vasc Interv Radiol ; 20(11): 1471-6, 2009 Nov.
Article En | MEDLINE | ID: mdl-19766017

PURPOSE: Chemical ablation of the gallbladder may be a useful alternative to surgery for inoperable disease. The purpose of this study was to investigate the feasibility of chemical ablation of the gallbladder with acetic acid in a canine model. MATERIALS AND METHODS: Five beagle dogs underwent percutaneous transhepatic cholecystostomy. Percutaneous occlusion of the cystic duct was performed with use of n-butyl cyanoacrylate (NBCA) and coils. After confirmation of occlusion of the cystic duct, sclerotherapy of the gallbladder was performed with 4-7 mL of 50% acetic acid through the drainage catheter. Acetic acid was retained for 20 minutes with intermittent position change. The drainage catheter was removed immediately after sclerotherapy. The dogs were euthanized 8 weeks after the procedure. The gallbladders and adjacent organs were evaluated grossly as well as microscopically. RESULTS: All dogs survived without serious complications during the experimental period. Sclerotherapy was technically successful in all dogs. Gross specimens of the gallbladder showed shrinkage and fibrotic change without retention of any bile, mucus, or pus. Histologic examinations from the body and fundus of the gallbladder demonstrated complete ablation of the mucosa. However, the neck region of the gallbladder near the cystic duct, where NBCA and coils for cystic duct occlusion were located, had focal areas of remnant or regenerating mucosa. CONCLUSIONS: Chemical ablation of the gallbladder with 50% acetic acid was effective and safe. Complete ablation was achieved in the majority of gallbladder mucosa except for a small portion located in the gallbladder neck.


Ablation Techniques/methods , Acetic Acid/administration & dosage , Gallbladder/drug effects , Gallbladder/pathology , Sclerosing Solutions/administration & dosage , Sclerotherapy/methods , Animals , Dogs
17.
AJR Am J Roentgenol ; 192(5): 1430-3, 2009 May.
Article En | MEDLINE | ID: mdl-19380573

OBJECTIVE: The purpose of this study was to evaluate the safety and effectiveness of analgesia with remifentanil for percutaneous transhepatic biliary drainage. SUBJECTS AND METHODS: Analgesia for percutaneous transhepatic biliary drainage was induced with remifentanil in 186 patients over a 1-year period. Remifentanil was administered IV with an infusion pump at 0.1 microg/kg/min as the usual dose and 0.15 microg/kg/min as the maximal dose. Selected patients with severe anxiety also received a 1-mg bolus of midazolam. Vital signs, sedation levels, and side effects were checked every 5 minutes during the procedure and recovery. The patients scored their pain subjectively on an 11-point numerical rating scale. RESULTS: The mean total dose of remifentanil was 116.3 microg (range, 32.5-200 microg). Midazolam was administered to 15 patients. Transient bradycardia occurred in 19 patients (10%). Hypotension did not develop in any patient. Respiratory depression occurred in four patients (2%). An appropriate level of sedation was obtained in 182 patients (98%), the modified Ramsay score being 2 (n = 164, 88%) or 3 (n = 18, 10%). Forty-nine of the patients (26%) indicated no pain (numeric rating, 0), 120 (64%) indicated mild pain (numeric rating, 1-3), and 16 (9%) indicated moderate pain (numeric rating, 4-6). One patient (1%) indicated severe pain (numeric rating, 7). CONCLUSION: Remifentanil is safe and highly effective for pain control during percutaneous transhepatic biliary drainage. This drug is a suitable option for analgesia during painful interventional radiology procedures.


Analgesics, Opioid/administration & dosage , Biliary Tract Diseases/therapy , Drainage/methods , Piperidines/administration & dosage , Adult , Aged , Aged, 80 and over , Analgesics, Opioid/adverse effects , Female , Humans , Male , Middle Aged , Pain Measurement , Piperidines/adverse effects , Radiography, Interventional , Remifentanil , Safety , Treatment Outcome
18.
J Vasc Interv Radiol ; 19(11): 1614-9, 2008 Nov.
Article En | MEDLINE | ID: mdl-18823794

PURPOSE: To evaluate technical success and clinical efficacy of crisscross-configured dual biliary stent implantation in patients with a biliary hilar tumor extending beyond the segmental ducts. MATERIALS AND METHODS: Between January 2002 and December 2006, two metallic stents were placed crossing each other in a hepatic hilum in 42 patients. One stent was placed between one right sectoral duct and the left hepatic duct and the other was placed between another right sectoral duct and the common bile duct. The patients ranged in age from 36 to 83 years (mean, 63.3 y) and included 26 men and 16 women. Technical success, clinical success, complications, and long-term results were analyzed by retrospective review. RESULTS: Stent placement was performed through two right accesses (n = 30), one right and one left access (n = 3), or two right accesses and one left access (n = 6). Successful "trisectoral" drainage was obtained with two stents in 41 patients (98%). In one case of initial technical failure, an additional stent was needed to connect the two previously placed stents. Clinical success was obtained in 34 of the remaining 36 patients (92%). No procedure-related major complication was observed. The median primary stent patency time was 187 days and the median patient survival time was 247 days. CONCLUSIONS: Crisscross-configured dual stent implantation is a feasible, safe, and effective method to maximize hepatic drainage with a minimal number of stents in patients with advanced biliary hilar malignancy.


Bile Duct Neoplasms/surgery , Drainage/instrumentation , Drainage/methods , Liver Neoplasms/surgery , Stents , Adult , Aged , Aged, 80 and over , Bile Duct Neoplasms/diagnostic imaging , Female , Humans , Liver Neoplasms/diagnostic imaging , Male , Middle Aged , Prosthesis Design , Radiography , Treatment Outcome
19.
J Vasc Interv Radiol ; 18(10): 1222-6, 2007 Oct.
Article En | MEDLINE | ID: mdl-17911511

PURPOSE: To evaluate the effectiveness and safety of treatment of high-flow priapism (HFP) with superselective transcatheter embolization at nine university hospitals. MATERIALS AND METHODS: Between May 1994 and October 2006, 27 patients underwent superselective embolization of the cavernous artery for HFP. Trauma was apparent in 22 patients, there was self-administered intracavernosal injection for erectile dysfunction in two, and the remaining three did not recall any penile or perineal trauma. The embolic agents used were autologous blood clot (n = 12), gelatin sponge (n = 12), microcoils combined with gelatin sponge (n = 1), polyvinyl alcohol (n = 1), and N-butyl cyanoacrylate (n = 1). Recurrence of priapism and change in erectile function were evaluated during a mean follow-up of 13 months. Differences in results between patients treated with autologous blood clot versus gelatin sponge were statistically analyzed with use of the chi(2) test. RESULTS: In 24 of 27 patients (89%), a single embolization was sufficient for complete resolution of priapism. Repeat embolization was required in two patients (7%), and in the remaining patient (4%), shunt surgery was performed after embolization as a result of HFP coexisting with corporeal venoocclusive dysfunction. Eighteen of 23 patients (78%) who had premorbid normal erectile function showed maintained potency during the follow-up period. There was no significant difference affecting required repeat embolization (P = .537) and change in quality of erection (P = .615) during the follow-up period between the autologous blood clot and gelatin sponge treatment groups. CONCLUSIONS: Superselective transcatheter embolization in the treatment of HFP is effective and ensures a high level of preservation of premorbid erectile function.


Embolization, Therapeutic/methods , Penile Diseases/complications , Penis/blood supply , Priapism/therapy , Vascular Fistula/complications , Adult , Aged , Child , Child, Preschool , Embolization, Therapeutic/adverse effects , Follow-Up Studies , Humans , Korea , Male , Middle Aged , Penile Diseases/diagnostic imaging , Penile Diseases/physiopathology , Penile Diseases/therapy , Penile Erection , Priapism/diagnostic imaging , Priapism/etiology , Priapism/physiopathology , Radiography , Recurrence , Regional Blood Flow , Retrospective Studies , Time Factors , Treatment Outcome , Vascular Fistula/diagnostic imaging , Vascular Fistula/physiopathology , Vascular Fistula/therapy
20.
AJR Am J Roentgenol ; 188(3): 647-51, 2007 Mar.
Article En | MEDLINE | ID: mdl-17312049

OBJECTIVE: The purpose of this study was to evaluate the radiologic and clinical effectiveness and long-term results of fluoroscopically guided balloon dilation of anastomotic strictures after total gastrectomy. CONCLUSION: Fluoroscopically guided balloon dilation is effective and safe and has encouraging long-term results in the management of benign anastomotic strictures after total gastrectomy.


Catheterization/methods , Esophageal Stenosis/diagnostic imaging , Esophageal Stenosis/therapy , Fluoroscopy/methods , Gastrectomy/adverse effects , Radiography, Interventional/methods , Adult , Aged , Esophageal Stenosis/etiology , Female , Humans , Longitudinal Studies , Male , Middle Aged , Treatment Outcome
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