RESUMEN
Salivary gland neoplasms account for 3% of all head and neck tumours. Pleomorphic adenoma (PA) is the most common salivary gland tumour that mainly occurs in the parotid gland, followed by minor salivary glands of the oral cavity, however, the occurrence of PA inside the jaw bones is exceedingly rare and very few cases have been reported in the literature. Inside jaw bones these lesions tend to imitate large osteolytic lesions encompass a diagnostic challenge. An exhaustive review of the literature revealed only 10 cases of central pleomorphic adenoma. We present a rare case of primary PA that occurred inside the mandible and was provisionally diagnosed as ameloblastoma.
Asunto(s)
Adenoma Pleomórfico , Ameloblastoma , Neoplasias Mandibulares , Humanos , Masculino , Adenoma Pleomórfico/diagnóstico , Adenoma Pleomórfico/patología , Ameloblastoma/diagnóstico , Ameloblastoma/patología , Diagnóstico Diferencial , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/patología , AdultoRESUMEN
Paragangliomas are neuroendocrine tumors similar to pheochromocytomas but arising from extra adrenal site. It is a very rare tumor in an intraoral site, we found a single case of intraoral paraganglioma in a literature, and hence as per our best knowledge this is only the second case of paraganglioma presented in an intraoral location. We present here a case report of paraganglioma on the ventral surface of the tongue. A 37 years old lady presented with a large asymptomatic swelling on the ventral surface of the tongue from one year. The past medical history and familial history were non relevant to the swelling. Surgical excision was performed and histopathological examination of the specimen revealed the diagnosis of extra adrenal paraganglioma. The case is being presented here for its rarity in an intraoral location.
RESUMEN
Dentinogenic ghost cell tumor (DGCT) is a very rare entity with controversies in its terminology and classification. It is the neoplastic solid counterpart of the calcifying odontogenic cyst (COC), which was first reported by Gorlin et al. in 1962. There are around 31 cases reported in the literature. The mean age of occurrence is 40.27 years, although very rarely is it associated with the pediatric age group. We are reporting a case of DGCT with dysplastic changes in an 11-year-old child which is very rare. The present case deals with the clinical, radiological, and histopathological aspects of the disease and the importance of an appropriate diagnosis. How to cite this article: Natani A, Borah S, Borah M, et al. Dentinogenic Ghost Cell Tumor of Mandible in a Pediatric Patient with Dysplastic Changes. Int J Clin Pediatr Dent 2020;13(S-1):S119-S121.
RESUMEN
Basaloid squamous cell carcinoma (BSCC) is a distinctive variant of squamous cell carcinoma (SCC) characterised by nests of basaloid cells. BSCC is an aggressive and rare tumor of head and neck region; and is relatively rare in oral cavity in comparison to SCC. Although, infrequent, but primary intra-osseous SCC (PIOSCC) has been reported in the jaws. There are separate diagnostic criteria for this lesion and a classification for primary intra-osseous carcinoma has been described. No evidence was found in the published literature about primary intra-osseous BSCC (PIOBSCC). We, herein, present a case of giant osteodestructive lesion of the posterior mandible which was diagnosed as PIOBSCC with a correlation of histopathological and immunohistochemical features. As per the best of our knowledge, this is the first case of PIOBSCC of the jaw. There is no diagnostic criterion of PIOBSCC in the literature owing to the extreme rarity of this tumor. A diagnostic criterion is proposed here to make the diagnosis of this tumor easier.
Asunto(s)
Carcinoma de Células Escamosas/diagnóstico , Mandíbula/diagnóstico por imagen , Neoplasias Mandibulares/diagnóstico , Osteotomía Mandibular/métodos , Biopsia/métodos , Carcinoma de Células Escamosas/cirugía , Humanos , Masculino , Mandíbula/cirugía , Neoplasias Mandibulares/cirugía , Radiografía Panorámica , Enfermedades Raras , Adulto JovenAsunto(s)
Histiocitosis de Células de Langerhans/diagnóstico , Mandíbula/diagnóstico por imagen , Osteólisis/diagnóstico por imagen , Radiografía Panorámica , Resorción Radicular , Tomografía Computarizada por Rayos X/métodos , Biopsia , Resorción Ósea , Preescolar , Diagnóstico Diferencial , Humanos , Masculino , Mandíbula/patologíaRESUMEN
Epitheloid hemangioendothelioma (EHE) is a rare vascular neoplasm of intermediate malignant potential. EHE commonly involves lungs, liver soft tissue, and bone. EHE is extremely rare in tongue and up to our best knowledge only nine cases of EHE of tongue reported in the literature. ClinicallyÙ EHE usually presents as an asymptomatic mass. Microscopically, EHE exhibits proliferation of epitheloid cells and spindle shaped endothelial cells. Epitheloid cells show cytoplasmic vacuoles with few cells containing RBCs. A 34-year-old male presented to our institution with the chief complain of swelling on the base of the tongue from eight months. Surgical excision was done. An extensive work up of immunohistochemistry was done using different markers including CD 31, CD 34, Ki 67, Factor VIII, and BCL2. Correlation of histopathology and immunohistochemistry confirmed the diagnosis of EHE. The follow up period of 2 years was uneventful.
RESUMEN
Spindle cell lipoma (SCL), also called as pleomorphic adenoma, is a rare variant of lipoma histopathologically characterized by an admixture of mature fat cells with spindle cells and occasionally mast cells with myxoid connective tissue stroma and thick bends of birefringent collagen. Although buccal mucosa is the most common location for oral lipomas, for SCL, it is an exceedingly rare location. We report a case of an asymptomatic swelling of buccal mucosa that simulated the features of neurofibroma on histopathological examination, and the final diagnosis of SCL was made on the basis of immunohistochemical features. This is the first documentation of oral SCL using SOX10 to achieve the final diagnosis.
Asunto(s)
Antígenos CD34/análisis , Lipoma/química , Neoplasias de la Boca/química , Neurofibroma/química , Factores de Transcripción SOXE/análisis , Adulto , Diagnóstico Diferencial , Humanos , Inmunohistoquímica , Masculino , Neoplasias de la Boca/diagnóstico , Neoplasias de la Boca/patología , Neurofibroma/diagnóstico , Neurofibroma/patologíaAsunto(s)
Cistoadenoma Papilar/patología , Glándula Parótida/diagnóstico por imagen , Neoplasias de la Parótida/patología , Biopsia , Cistoadenoma Papilar/cirugía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias de la Parótida/cirugía , Tomografía Computarizada por Rayos X , Resultado del TratamientoAsunto(s)
Antígenos Específicos del Melanoma/metabolismo , Neoplasias de Células Epitelioides Perivasculares/metabolismo , Neoplasias de Células Epitelioides Perivasculares/patología , Biomarcadores de Tumor/análisis , Niño , Femenino , Humanos , Inmunohistoquímica , Antígenos Específicos del Melanoma/análisis , Neoplasias de Células Epitelioides Perivasculares/cirugía , Antígeno gp100 del MelanomaAsunto(s)
Neoplasias Óseas/patología , Neoplasias Maxilomandibulares/patología , Osteoma Osteoide/patología , Neoplasias Óseas/cirugía , Humanos , Neoplasias Maxilomandibulares/cirugía , Masculino , Persona de Mediana Edad , Osteoma Osteoide/cirugía , Procedimientos Quirúrgicos Operativos , Resultado del TratamientoRESUMEN
Central Giant Cell Granuloma (CGCG) is a benign tumor of jaw. As compared to males, females are more commonly affected. Mandible is the common site of occurrence. Aneurysmal bone cysts (ABCs) are cystic lesions which are expansile osteolytic blood-filled lesions. These are commonly seen in the mandible, and they also show gender-predilection towards females. Concurrence of both the lesions is rarely reported. The treatment of both CGCG and ABC depends upon the extent of the lesions as well as on their nature. Due to aggressive nature of the lesions, these usually cause disfigurement of the patients' face. Wide excision is the treatment modality for aggressive lesions to avoid recurrence. We present a case of 28-year male who showed CGCG along with ABC in the same lesion, a rare concurrence.
Asunto(s)
Quistes Óseos Aneurismáticos/diagnóstico , Granuloma de Células Gigantes/diagnóstico , Mandíbula/diagnóstico por imagen , Resorción Radicular/diagnóstico por imagen , Adulto , Biopsia , Quistes Óseos Aneurismáticos/complicaciones , Granuloma de Células Gigantes/complicaciones , Humanos , Masculino , Radiografía PanorámicaRESUMEN
Adenoid cystic carcinoma (ACC) is a malignant tumor of salivary glands characterized histopathologically by biphasic epithelial tumor comprised of myoepithelial and ductal cells. There is a paucity of the literature regarding the immunohistochemical labelling of ACC arising in minor salivary glands. This paper reports an additional case of palatal ACC with an emphasis on its immunohistochemical staining using three different markers. Immunohistochemistry allows a better differentiation of ACC with its closest imitators, like polymorphous low grade adenocarcinoma (PLGA), considering that the latter is lesser aggressive and demands a lesser aggressive treatment approach.
Asunto(s)
Carcinoma Adenoide Quístico/metabolismo , Antígeno Ki-67/análisis , Neoplasias Palatinas/metabolismo , Proteínas Proto-Oncogénicas c-kit/metabolismo , Neoplasias de las Glándulas Salivales/metabolismo , Glándulas Salivales Menores/patología , Glándulas Salivales/patología , Adulto , Biomarcadores de Tumor/análisis , Carcinoma Adenoide Quístico/patología , Humanos , Inmunohistoquímica , Masculino , Neoplasias Palatinas/patología , Hueso Paladar/patología , Neoplasias de las Glándulas Salivales/patología , Proteína p53 Supresora de TumorRESUMEN
Centrally occurring salivary gland tumors are rare. Because of a considerable overlap between the clinical and histopathological features, this group of tumors often produces a diagnostic difficulty to the clinicians and oral pathologists. Acinic cell carcinoma (ACC) is an unusual, low-grade, malignant salivary gland tumor that represents approximately 2% of the salivary gland tumors with almost 90% arising in the parotid gland. The rest involve the submandibular and the minor salivary gland. ACC of the jaw is extremely rare and, to our knowledge, only 8 cases have been reported in the English literature. Herein, a case of primary intraosseous ACC of the mandible in a 31-year-old woman is presented. The present case is unique, as the central ACC has never been reported in a patient in the third decade of life. The complete surgical removal of the tumor was carried out under general anesthesia along with the extraction of teeth #31, #32, #41, and #42. The follow-up period of 1-year was uneventful.