Your browser doesn't support javascript.
loading
: 20 | 50 | 100
1 - 20 de 60
1.
J Coll Physicians Surg Pak ; 32(4): S28-S30, 2022 04.
Article En | MEDLINE | ID: mdl-35633003

Extramedullary hematopoiesis (EMH) is a physiological compensatory mechanism that develops in response to ineffective or insufficient hematopoiesis. Although the liver and spleen are the most common sites, EMH may occur anywhere in the body. Peri-renal involvement in EMH is quite rare and mimics tumoral lesions. To our knowledge, 12 peri-renal EMH cases have been reported in the literature so far.  A 57-year woman was admitted to our hospital with non-specific abdominal pain. She had a history of chronic renal failure. On physical examination, diffuse abdominal tenderness and mild rigidity were detected. Blood tests revealed bicytopenia and elevated acute phase reactants. On non-contrast abdominal computed tomography (CT) scan, two peri-renal mass lesions of 4.5 cm and 4 cm were detected incidentally on the right side. Tumoral lesions were considered in the differential diagnosis, and magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) were performed. Lesions showed mild hypermetabolic activity (SUVmax: 4,68) on PET-CT images. For the definitive diagnosis, an ultrasound-guided core needle biopsy was performed. The histopathological examination was consistent with EMH. This case aims to highlight the peri-renal involvement of EMH, which mimics renal and peri-renal malignancies.


Hematopoiesis, Extramedullary , Female , Humans , Magnetic Resonance Imaging , Positron Emission Tomography Computed Tomography , Tomography, X-Ray Computed , Ultrasonography
2.
Sisli Etfal Hastan Tip Bul ; 56(1): 113-118, 2022.
Article En | MEDLINE | ID: mdl-35515969

Objectives: Even though magnetic resonance imaging has been described as the most effective imaging method for the diagnosis of liver fibrosis, an accepted magnetic resonance imaging (MRI) technique is yet to be defined. The aim of this study is to determine the efficiency of MRI in the staging of liver fibrosis. Methods: Patients with chronic hepatitis B infection and had upper abdominal MRI with hepatocyte specific contrast agent were evaluated. Twenty-nine patients that had undergone liver biopsy were included in the study. ADC, FA, and signal intensity values of liver parenchyma were measured by two observers and contrast enhancement index (CEI) was calculated as well. Patients were grouped as early (A) and late fibrosis(B) according to Ishak grading system and then the correlations between the stage and MRI findings were analysed. The intraclass correlation coefficient was used to analyze the inter-rater agreements. ADC, FA, and CEI were compared with Student t-test between early and late fibrosis groups. Pearson's correlation was used to assess the correlation between ADC and FA values. Spearman correlation was used to evaluate the relationship between pathologic fibrosis grade and MRI parameters that were measured. Results: Twenty-two patients were staged as 1 and 2 (group A), seven patients were staged as 3 and above fibrosis(group B). Statistically, there was a strong, negative correlation between the FA values and the degree of fibrosis (r=-0.582, p=0.001). There was no correlation between the CEI and hepatocyte activity index (r=-0.88, p=0.655) and degree of fibrosis (r=0.0001, p=0.997). In terms of FA values, there was a statistically significant difference between two groups (group A=0.429 ± 0.06, group B=0.349 ± 0.06) (p=0.004). Conclusion: Correlation of FA values with fibrosis stage and significant difference in FA values between early-late stage fibrosis patients shows that diffusion tensor imaging can be a promising technique in the staging and follow-up of liver fibrosis.

3.
J Coll Physicians Surg Pak ; 32(12): SS209-SS211, 2022 12.
Article En | MEDLINE | ID: mdl-36597341

Primary hepatic angiosarcoma (PHA) is a sporadic and aggressive tumour of the liver that originates from mesenchymal cells and represents less than 2% of all primary liver tumours. It is known to be associated with several environmental and industrial carcinogens; however, in 75% of cases, aetiology remains unclear. Patients generally present with nonspecific symptoms and laboratory findings. Imaging has a limited role in the diagnosis.  We herein present a case of a 52-year-old man with a history of hepatitis B-related cirrhosis who was referred to our hospital for liver transplantation assessment. Magnetic resonance imaging (MRI) revealed two small nodular lesions of 5 and 6 mm in segment IV of the liver, categorised as Liver Imaging Reporting and Data System (LI-RADS) category 3. The patient was discussed at a multidisciplinary tumour meeting, and an MRI follow-up in three months was planned. Three months later, MRI depicted a substantial increase in the lesion size measured 8.5 cm. An ultrasound-guided tru-cut biopsy was performed, and the diagnosis of PHA was confirmed by pathology. In this report, we aim to highlight PHA's MRI features and underline this rare entity's rapid and fatal progression.


Carcinoma, Hepatocellular , Hemangiosarcoma , Liver Neoplasms , Male , Humans , Middle Aged , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/complications , Hemangiosarcoma/diagnostic imaging , Hemangiosarcoma/surgery , Magnetic Resonance Imaging/methods
4.
Sisli Etfal Hastan Tip Bul ; 55(1): 12-17, 2021.
Article En | MEDLINE | ID: mdl-33935530

OBJECTIVES: To compare the efficacy of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) and magnetic resonance imaging (MRI) in the detection of liver metastases originating from the gastrointestinal system (GIS) and the pancreaticobiliary (PB) system. METHODS: This retrospective study included 42 patients with primary GIS (stomach or colorectal) or PB system malignancies that metastasized to the liver, histopathologically confirmed diagnoses, and MRI and 18F-FDG PET/CT images. The MRI and 18F-FDG PET/CT images were analyzed. Student's t-test was used to compare the two modalities in terms of determining the number of metastases, and Cohen's kappa test was conducted to determine the agreement between the modalities. RESULTS: Twenty-eight (66.7%) of the patients included in this study were male, and the mean age was 60.67±9.4 years. Colon (n=25; 59.5%) and pancreatic (n=7; 16.6%) adenocarcinomas were the most common primary tumors that had metastasized to the liver. MRI detected more metastases in 12 (28.5%) patients, less in seven (16.6%), and an equal number of metastases in 23 (54.7%). No statistically significant difference was observed between the number of metastases detected by MRI and 18F-FDG PET/CT (7.55±7.96 and 6.36±7.28, respectively; p=0.11). There was a moderate agreement between the two modalities (kappa value=0.423). Most of the metastases detected on MRI but not seen on 18F-FDG PET/CT (n=10, 23.8%) were lesions smaller than 10 mm. For the eight (19%) patients with lymph node metastases, the number of metastatic lymph nodes detected by MRI and 18F-FDG PET/CT was similar (12 and 14, respectively, p>0.05). CONCLUSION: MRI can detect small lesions at an early stage, and 18F-FDG PET/CT shows the metabolic activity of lesions; therefore, the combined use of the two modalities can potentially offer a beneficial outcome for patients.

5.
Sisli Etfal Hastan Tip Bul ; 54(1): 47-51, 2020.
Article En | MEDLINE | ID: mdl-32377133

OBJECTIVES: Computed tomography-guided core needle biopsy has an important role in the accurate histopathological diagnosis of lung masses. The present study aims to share our results of computed tomography-guided percutaneous core needle biopsy of lung masses. METHODS: A total of 117 patients had computed tomography-guided percutaneous core needle biopsy for lung masses between January 2017-September 2019 in our institution. In this study, these patients' post-procedural complications, diagnostic-yield-rates and radiological-histopathological correlations were evaluated retrospectively. RESULTS: Complications occurred in 23 (20%) patients (20 (17%) of pneumothorax; 3 (3%) of hemorrhage). Chest-tube-drainage was needed in five (4%) of all patients. No significant difference was found between complication rates and patient gender/age, tumor volume/localization or needle-path-length (p>0.05). In 77 of the 85 (91%) primary-lung-cancer-cases radiological and pathological diagnostic results were correlated. CONCLUSION: Computed tomography-guided core needle biopsy has a high diagnostic yield rate with acceptable complication rates in the diagnosis of lung masses.

6.
Med Ultrason ; 17(4): 557-60, 2015 Dec.
Article En | MEDLINE | ID: mdl-26649356

Median arcuate ligament syndrome (MALS), also known as celiac artery compression syndrome is a rare condition characterized by chronic mesenteric ischemia, secondary to the compression of the celiac artery by the median arcuate ligament. Occasionally, in addition to the celiac artery, the superior mesenteric artery may be partially compressed by the median arcuate ligament. We report a case with complaints of chronic abdominal pain from compression of both the celiac artery and the superior mesenteric artery due to MALS, which was primarily detected by Doppler ultrasound. The diagnosis was confirmed with CT-angiography.


Celiac Artery/abnormalities , Celiac Artery/diagnostic imaging , Constriction, Pathologic/diagnostic imaging , Mesenteric Artery, Superior/diagnostic imaging , Mesenteric Vascular Occlusion/diagnostic imaging , Ultrasonography, Doppler/methods , Adult , Diagnosis, Differential , Humans , Male , Median Arcuate Ligament Syndrome
7.
Med Ultrason ; 17(2): 248-51, 2015 Jun.
Article En | MEDLINE | ID: mdl-26052578

Ectopic cervical thymus (ECT) is an uncommon cause for cervical mass in the pediatric age group. Ultrasound and magnetic resonance imaging findings of the mass (located along the thymic descent pathway along the thymopharyngeal tract and has identical echostructure and signal intensities to the native thymus in the superior mediastinum) would lead to the diagnosis. The diagnosis is confirmed by fine needle aspiration biopsy or histopathology after resection. The management of ECT is a conservative follow up, except in symptomatic cases with tracheal compression and histologically confirmed neoplasia where surgery is indicated. We present the case of ECT presenting as a left upper neck mass in a 12 year old girl.


Choristoma/diagnostic imaging , Choristoma/pathology , Magnetic Resonance Imaging , Neck/diagnostic imaging , Neck/pathology , Thymus Gland , Biopsy, Needle , Child , Diagnosis, Differential , Female , Humans , Ultrasonography
8.
J Craniofac Surg ; 26(1): 87-90, 2015 Jan.
Article En | MEDLINE | ID: mdl-25534057

OBJECTIVE: The objective of this study was to radiologically determine frontal sinus drainage pathway variations with respect to superior attachment of uncinate process (SAUP) and their effect on prevalence of frontal rhinosinusitis. DESIGN: This was a retrospective cohort study. METHODS: Computed tomography scans of the 919 frontal sinus sides of 460 patients (252 female, 208 male; mean age, 35.1 ± 10.5 years) who were candidates for endoscopic sinus surgery were evaluated retrospectively between August 2012 and January 2013 by 3 radiologists to determine the SAUP types and the presence of frontal rhinosinusitis. RESULTS: The frontal sinus outflow tract was localized medial to the SAUP in 651 frontal sinus sides and lateral to the SAUP in 268 sides. We determined 3 types (types 7, 8, and 9) of SAUP in addition to 6 types defined in literature. The most common type of SAUP was type 3 (n = 332, 36.1%) followed by type 2 (n = 256, 27.8%) and type 7 (n = 160, 17.4%). Of the evaluated sides, 316 (34.3%) had frontal rhinosinusitis. Frontal rhinosinusitis was more common in the sides where the frontal sinus outflow tract was localized medial to the SAUP than those localized lateral (37.2% vs 27.6%, P = 0.006). CONCLUSIONS: Endoscopic approach to frontal recess usually requires uncinectomy, and it is necessary to know SAUP to prevent postoperative retained superior portion of the uncinate process. The location of frontal sinus outflow tract on the SAUP affects the prevalence of frontal rhinosinusitis as well. Frontal rhinosinusitis is significantly more common when the frontal sinus outflow tract was localized medial rather than lateral to the SAUP. LEVEL OF EVIDENCE: 2b.


Anatomic Variation , Frontal Sinus/diagnostic imaging , Frontal Sinusitis/etiology , Rhinitis/etiology , Adolescent , Adult , Aged , Child , Cohort Studies , Endoscopy/methods , Ethmoid Bone/diagnostic imaging , Female , Follow-Up Studies , Frontal Sinusitis/diagnostic imaging , Frontal Sinusitis/surgery , Humans , Male , Middle Aged , Multidetector Computed Tomography/methods , Nasal Septum/diagnostic imaging , Retrospective Studies , Rhinitis/diagnostic imaging , Rhinitis/surgery , Skull Base/diagnostic imaging , Turbinates/diagnostic imaging , Young Adult
9.
Quant Imaging Med Surg ; 4(5): 307-12, 2014 Oct.
Article En | MEDLINE | ID: mdl-25392818

AIM: To evaluate the diagnostic quality of a new multiple detector-row computed tomography angiography (MDCT-A) protocol using low dose radiation and low volume contrast medium techniques for evaluation of non-cardiac chest pain. METHODS: Forty-five consecutive patients with clinically suspected noncardiac chest pain and requiring contrast-enhanced chest computed tomography (CT) were examined. The patients were assigned to the protocol, with 80 kilovolt (peak) (kV[p]) and 150 effective milliampere-second (eff mA-s). In our study group, 40 mL of low osmolar contrast material was administered at 3.0 mL/s. RESULTS: In the study group, four patients with pulmonary embolism, four with pleural effusion, two with ascending aortic aneurysm and eight patients with pneumonic consolidation were detected. The mean attenuation of the pulmonary truncus and ascendant aortic locations was considered 264±44 and 249±51 HU, respectively. The mean effective radiation dose was 0.83 mSv for MDCT-A. CONCLUSIONS: Pulmonary artery and the aorta scanning simultaneously was significantly reduced radiation exposure with the mentioned dose saving technique. Additionally, injection of low volume (40 cc) contrast material may reduce the risk of contrast induced nephropathy, therefore, facilitate the diagnostic approach. This technique can be applied to all cases and particularly patients at high risk of contrast induced nephropathy due to its similar diagnostic quality with a low dose and high levels of arteriovenous enhancement simultaneously.

11.
Iran J Radiol ; 11(1): e3555, 2014 Jan.
Article En | MEDLINE | ID: mdl-24693297

BACKGROUND: Hepatic fibrosis is a typical complication of chronic liver diseases resulting in cirrhosis that remains a major public health problem worldwide. Liver biopsy is currently the gold standard for diagnosing and staging hepatic fibrosis. Percutaneous liver biopsy; however, is an invasive procedure with risks of complications. Therefore, there is need for alternative non-invasive techniques to assess liver fibrosis and chronic liver diseases. In recent years, MRI techniques, including diffusion weighted imaging (DWI), have been developed for in vivo quantification of liver fibrosis. OBJECTIVES: The purpose of this study is to evaluate the utility of diffusion weighted MRI in the diagnosis and quantification of the degree of hepatic fibrosis and to investigate the influence of b-value. PATIENTS AND METHODS: Twenty-four patients (13 males, 11 females), with a mean age of 46 years (36-73 years) diagnosed as chronic hepatitis and histopathologically proven liver fibrosis and 22 other patients (8 males, 14 females) with no clinical or biochemical findings of liver disease, with a mean age of 51.2 years (32-75 years) were included in the study. All patients with chronic hepatitis underwent percutaneous liver biopsy by an experienced hepatologist without sonographic guidance. The Knodell histology activity index (HAI) for grading of necroinflammatory changes and Metavir scoring system for staging of the liver fibrosis were used to record the severity of the disease. All patients were examined with a 1.5 Tesla MRI system and the patients underwent diffusion weighted imaging (DWI) with a routine hepatic MRI protocol. Different b-values including 250, 500, 750, and 1000 sec/mm (2) were used to calculate apparent diffusion coefficients. RESULTS: We detected decreased apparent diffusion coefficient values in patients with hepatic fibrosis compared to patients without chronic hepatitis and there was a trend toward decrease in hepatic apparent diffusion coefficient values with an increasing degree of fibrosis. CONCLUSIONS: Our findings suggest that hepatic apparent diffusion coefficient measurement with a b-value of 750 sec/mm (2) or greater is useful in accurate quantification of liver fibrosis and necroinflammation.

12.
Acta Radiol ; 55(6): 654-60, 2014 Jul.
Article En | MEDLINE | ID: mdl-24043882

BACKGROUND: Although diffusion-weighted magnetic resonance imaging imaging (DW-MRI) is commonly used to characterize hepatic lesions, the literature is sparse about the use of MR diffusion tensor imaging (DTI) in this regard. By using DTI, one is able to obtain not only apparent diffusion coefficients (ADCs) but also fractional anisotropy (Fa) values. PURPOSE: To evaluate DTI using ADC and Fa values in the imaging of hepatic cysts, hemangiomas, and metastases. MATERIAL AND METHODS: Sixty-six patients with 77 lesions were examined with DTI. There were 32 metastases, 13 cysts, and 32 hemangiomas. Two radiologists performed ADC and Fa measurements. Inter-observer agreement was evaluated using Bland-Altman plots. ADCs and Fa values were correlated using Pearson correlation. The differences were compared using ANOVA and Tukey tests. A ROC analysis was applied; sensitivities and specificities were calculated. RESULTS: The inter-observer agreement was very good. The correlation between ADC and Fa was negative, weak, and significant (r = -0.36). The mean ADC value of cysts (3.30 ± 0.8 × 10(-3) mm(2)/s) was significantly higher than that of hemangiomas (2.23 ± 0.5 × 10(-3) mm(2)/s) and metastases (1.62 ± 0.4 × 10(-3) mm(2)/s). The mean Fa value of cysts (0.2 ± 0.05) was significantly lower than hemangiomas (0.37 ± 0.1) and metastases (0.46 ± 0.1). The Az values for discriminating metastases from benign hepatic lesions for ADC and Fa value were 0.885 and 0.731, respectively. The sensitivity and specificity of ADC and Fa were 87.5% and 84.4%, and 78.1% and 57.8%, respectively. The Az value for discriminating cysts from hemangiomas for Fa was 0.96. The sensitivity and specificity were 90.6% and 92.3%, respectively. CONCLUSION: Fa values may play a supportive role in the imaging of liver lesions. Whereas metastases tend to have low ADCs and high Fa values, cysts have high ADCs and low Fa values and hemangiomas have high ADCs and high Fa values.


Cysts/diagnosis , Diffusion Tensor Imaging/methods , Hemangioma/diagnosis , Liver Diseases/diagnosis , Liver Neoplasms/secondary , Magnetic Resonance Imaging/methods , Analysis of Variance , Anisotropy , Diagnosis, Differential , Female , Humans , Image Processing, Computer-Assisted/methods , Liver/pathology , Liver Neoplasms/diagnosis , Male , Middle Aged , Neoplasms, Second Primary/diagnosis , Neoplasms, Second Primary/secondary , Observer Variation , ROC Curve , Retrospective Studies , Sensitivity and Specificity
13.
Clin Imaging ; 38(2): 170-3, 2014.
Article En | MEDLINE | ID: mdl-24231624

The aim of the present study was to investigate the diagnostic significance of visualization of periesophageal fat pad in ultrasonography or computed tomography for sliding hiatal hernias. Forty-six controls and 21 esophageal hiatal hernia patients were compared in terms of sonographic and tomographic esophageal diameters. We suggest that absence of periesophageal fat pad sign in ultrasonography or computerized tomography is a noteworthy finding that calls for further investigation for the diagnosis of sliding hiatal hernias.


Adipose Tissue/diagnostic imaging , Esophagus/diagnostic imaging , Hernia, Hiatal/diagnostic imaging , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective Studies , Tomography, X-Ray Computed , Ultrasonography , Young Adult
14.
Clin Imaging ; 37(2): 232-8, 2013.
Article En | MEDLINE | ID: mdl-23465973

We evaluated the quantitative diffusion-weighted magnetic resonance imaging (DW-MRI) for parotid masses. Seventy-five patients with 81 focal parotid masses were included. Following DW-MRI, 73 masses underwent surgical biopsy/resection, 6 underwent ultrasonography-guided fine-needle aspiration, and 2 underwent both procedures. The mean apparent diffusion coefficient (ADC) of benign tumors (n=49, 1.72×10(-3) mm(2)/s) was higher than that of malignant tumors (n=32, 1.05×10(-3) mm(2)/s) (P<.001). ADC was 2.15×10(-3) mm(2)/s for pleomorphic adenomas, which was higher than that for other tumors (P<.001 for all). ADC cutoff was 1.315 for distinguishing between pleomorphic adenomas and others including malignant tumors. Therefore, DW-MRI may be useful for distinguishing between pleomorphic adenomas and other parotid masses.


Diffusion Magnetic Resonance Imaging/methods , Parotid Gland/pathology , Parotid Neoplasms/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Chi-Square Distribution , Child , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Parotid Neoplasms/pathology , ROC Curve , Sensitivity and Specificity , Statistics, Nonparametric
15.
Acad Radiol ; 20(4): 453-6, 2013 Apr.
Article En | MEDLINE | ID: mdl-23498986

RATIONALE AND OBJECTIVES: Diagnostic measures that can be used for sliding hiatal hernia are barium swallow radiography, endoscopy, manometry, and computed tomography. The aim of this study was to evaluate the diagnostic accuracy of transabdominal ultrasonography for sliding hiatal hernias. MATERIALS AND METHODS: This retrospective study was performed in the radiology department of a tertiary care center between May 2011 and May 2012. Twenty-one patients (10 females, 11 males) with sliding hiatal hernias and 41 controls (37 females, 4 males) were enrolled in this study. Esophageal hiatal diameters measured by ultrasonography and computerized tomography were compared. Correlation was tested via Pearson correlation analysis. RESULTS: The average age of patients and controls were 58.6 and 40.1, respectively. There was a statistically significant difference between esophageal hiatal diameters measured via ultrasonography in patients (31.7 mm) and controls (11.6 mm) (P < .001). Similarly, esophageal hiatal diameters measured via computed tomography in patients (31.4 mm) was statistically significantly higher than controls (11.5 mm) (P < .001). The average body mass index of patients (28.3) was higher than that of control group (P = .015). Ultrasonographic measurements were correlated well with tomographic results (P = .000, r = 0.995). CONCLUSION: Ultrasonography seems to be a valuable, safe, and practical alternative that avoids the side effects of contrast agents in the diagnosis of sliding hiatal hernias. Overall, we suggest that inclusion of ultrasound in the initial diagnostic steps for patients with sliding hiatal hernias may reduce the requirement for more expensive procedures.


Hernia, Hiatal/diagnostic imaging , Adult , Aged , Aged, 80 and over , Contrast Media , Female , Humans , Male , Middle Aged , Tomography, X-Ray Computed , Ultrasonography
16.
Can Assoc Radiol J ; 64(4): 351-7, 2013 Nov.
Article En | MEDLINE | ID: mdl-23267522

Despite advances in technology, the radiologic assessment of certain head and neck lesions may still pose difficulties because of the complex anatomy of this region, the small and mobile structures that this region harbors, and the apposition of mucosal surfaces in the neutral position. Certain maneuvers have been described in the literature to overcome these difficulties. We review the use of the Valsalva and the modified Valsalva maneuver, the puffed-cheek technique, phonation, and inspiration, with possible applications in head and neck imaging.


Head and Neck Neoplasms/diagnosis , Magnetic Resonance Imaging/methods , Tomography, X-Ray Computed/methods , Diagnosis, Differential , Humans , Inhalation/physiology , Phonation/physiology , Respiratory Physiological Phenomena , Valsalva Maneuver/physiology
17.
J Comput Assist Tomogr ; 36(4): 367-74, 2012.
Article En | MEDLINE | ID: mdl-22805662

OBJECTIVE: The purpose of this study was to assess the utility of diffusion-weighted and quantitative chemical-shift magnetic resonance imaging in the differentiation of adrenal adenomas and metastases. METHODS: One hundred eight patients (45 men and 63 women; mean age, 57 years) with 126 adrenal masses were prospectively evaluated by magnetic resonance imaging in this study. Signal intensity and apparent diffusion coefficient (ADC) measurements were performed on axial in- and opposed-phase T1-weighted gradient-echo images and on diffusion-weighted images, respectively. Adrenal signal intensity index (ASII), adrenal-to-spleen chemical-shift ratio (ASR), and ADC values were assessed separately. The threshold values of more than 16.5% for ASII and less than 0.71 for ASR were regarded as highly suggestive of adenoma diagnosis. We also investigated whether a cutoff value for ADC could be found in distinguishing adenomas from metastases. Final diagnoses of adrenal lesions were based on follow-up imaging, histopathologic proof, and adrenal washout study. Apparent diffusion coefficient values of adenomas and metastases were compared by using the Student t test, and ASII and ASR values of the lesions were compared by using the Mann-Whitney U test, and a P < 0.05 was accepted as statistically significant. Receiver operating characteristic curve analysis and sensitivity, specificity, positive and negative predictive values, and overall accuracies were calculated. RESULTS: Final analysis yielded 96 adenomas and 30 metastases. With the commonly used 16.5% threshold value for ASII, we obtained a 94.8% sensitivity, 93.3% specificity, 84.8% positive predictive value, and 97.8% negative predictive value. The overall accuracy was found as 94.4%. When we applied a 0.71 threshold value for ASR, it yielded a 91.7% sensitivity, 100% specificity, 78.9% positive predictive value, and a 100% negative predictive value. The overall accuracy was 93.6%. The mean ADC values were found to be 1.35 ± 0.19 × 10⁻³ mm²/s and 1.32 ± 0.34 × 10⁻³ mm²/s for adenomas and metastases, respectively. The difference between the groups with these ADC values was not statistically significant (P = 0.673). The receiver operating characteristic analysis could not determine a clear cutoff value for the differentiation of adenomas from metastases. CONCLUSIONS: We can advocate that a chemical-shift magnetic resonance imaging using quantitative parameters (ie, ASII and ASR formulas) has an important role in the distinction of adenomas from metastases. These 2 techniques seem to provide close sensitivity, specificity, and accuracy levels. But diffusion-weighted imaging using quantitative ADC measurements is not of value in this differential diagnosis because of the substantial overlapping of ADC values between adenomas and metastases.


Adrenal Cortex Neoplasms/pathology , Adrenocortical Adenoma/pathology , Magnetic Resonance Imaging/methods , Adult , Aged , Aged, 80 and over , Diffusion Magnetic Resonance Imaging , Female , Humans , Male , Middle Aged , Neoplasm Metastasis , Predictive Value of Tests , Prospective Studies , ROC Curve , Sensitivity and Specificity , Statistics, Nonparametric
18.
J Comput Assist Tomogr ; 36(4): 416-20, 2012.
Article En | MEDLINE | ID: mdl-22805670

OBJECTIVE: To evaluate the accuracy of dynamic laryngeal computed tomography (DLCT) for the detection of vocal cord mobility in larynx cancer. METHODS: Vocal cord mobility of 44 patients (36 men; age range, 49-81 years) with larynx cancer was examined; 13 patients were excluded (owing to poor image quality or bilateral vocal cord involvement), and vocal cord mobility was evaluated for the remaining 31 patients qualitatively and quantitatively with dynamic laryngeal computed tomography during phonation, inspiration, and Valsalva maneuver phase. RESULTS: The mobile cords were laterally positioned in a straight configuration on inspiration phase. Phonation phase images revealed medial displacement with protrusion of the cords (shoulder sign) and ventricular niche (31 patients/42 cords). Fixed cords (13 patients/13 cords) conserved their configuration and location during all phases. The distances of the vocal cords to the midline were measured based on the images obtained during inspiration and Valsalva maneuvers. The mean ± SD difference between the movement distances of cords measured during each phase was as follows: 6.16 ± 1.64 mm for the mobile cord (n = 42) and 3.17 ± 0.78 mm for the impaired cord (n = 7) on the midcoronal plane (P = 0.0001). A comparison between the mean distance values of the mobile, impaired and fixed cords groups revealed significant distance. CONCLUSIONS: Dynamic laryngeal computed tomography of the larynx of patients with laryngeal cancer can be used as a supplemental tool to examine cord mobilization for accurate T-staging (particularly for patient laryngoscopy, which is difficult to perform), and can provide additional information to physicians.


Carcinoma, Squamous Cell/diagnostic imaging , Laryngeal Neoplasms/diagnostic imaging , Tomography, X-Ray Computed/methods , Vocal Cord Paralysis/diagnostic imaging , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/physiopathology , Contrast Media , Female , Humans , Inhalation , Iohexol/analogs & derivatives , Laryngeal Neoplasms/physiopathology , Male , Middle Aged , Phonation , Valsalva Maneuver , Vocal Cord Paralysis/physiopathology
19.
Med Ultrason ; 14(1): 24-8, 2012 Mar.
Article En | MEDLINE | ID: mdl-22396935

OBJECTIVE: The purpose of this study was to define the criteria for use in differentiating benign and malignant nodules with the help of the receiver operating characteristic analysis and to increase the objective diagnostic accuracy of ultrasonography. MATERIALS AND METHODS: A total of 363 patients (307 women, 56 men) with 363 nodules (22 malignant and 341 benign nodules) were included in the study. The presence and absence of each US feature of the evaluated nodule - shape taller than wide, irregular margin, hypoechogenicity, microcalcification, and intranodular vascularity - were scored 1 and 0, respectively. The total ultrasound score was obtained by the summing up of each positive ultrasound findings for malignancy. The effect of the total US score in the discrimination of benign and malignant nodules was analysed using ROC analysis. RESULTS: The cut off values of US score at maximum sensitivity and specificity for nodules larger and smaller than one centimeter were two (Az: 0.783) and three (Az: 0.935), respectively. For nodules greater than one centimeter, the calculated diagnostic performances including sensitivity, specificity, positive predictive value and negative predictive value, and accuracy were 62.5%, 91.5%, 30.3%, 97.7%, and 89,9%, respectively. For nodules smaller or equal to one centimeter; the sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 83.3%, 94.9%, 62.5%, 98.2% and 93.8%, respectively. CONCLUSION: Using ultraound, thyroid nodules can be characterized effectively. The number of the US features used in this distinction varies in respect to the nodule size.


Image Enhancement/methods , Image Interpretation, Computer-Assisted/methods , Thyroid Nodule/diagnostic imaging , Ultrasonography/methods , Female , Humans , Male , Middle Aged , ROC Curve , Reproducibility of Results , Sensitivity and Specificity
20.
J Clin Ultrasound ; 40(7): 448-50, 2012 Sep.
Article En | MEDLINE | ID: mdl-21953240

We present a case of a 48-year-old female with a history of cholecystectomy and recurrent attacks of pancreatitis whose initial abdominal sonography (US) revealed multiple conglomerated stones in the descending part of the duodenum. Abdominal CT, MRI, and magnetic resonance cholangiopancreatography showed the same findings. The distended sacciform distal intramural segment of the common bile duct was protruding into the duodenum. The imaging findings explained the etiology of the patient's recurrent attacks of pancreatitis and led to surgical excision of the choledococele.


Choledochal Cyst/diagnostic imaging , Pancreatitis/etiology , Choledochal Cyst/complications , Female , Humans , Middle Aged , Recurrence , Ultrasonography
...