[Induction of long-term depression (with anxiety and fear components) by immunization of rats against pargyline]. / Induktsiia dlitel'nogo sostoianiia depressii (s komponentami trevozhnosti i strakha) immunizatsiei krys k pargilinu.

The active immunization of albino rats against pargyline (a MAO B inhibitor) induced the formation of antibody to pargyline and results in deep depressive changes and fear. These changes were observed within 6 weeks after the first immunization. Therefore, it opens the possibility to model depression long by exerting the minimum influences. There was also a long-term modulation of craving for alcohol.