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1.
Ann Acad Med Singap ; 38(2): 136-8, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19271041

RESUMEN

INTRODUCTION: The objective of this study was to determine the necessity of further evaluation of patients presented with herpes zoster (HZ) to the Emergency Department for the underlying decreased cell-mediated immunity. MATERIALS AND METHODS: The data of 132 adult patients presenting with HZ to the Emergency Department were collected from the computerised database of Akdeniz University Hospital. The following data were recorded: demographic data and underlying diseases during onset of HZ and laboratory results (white blood cell counts, blood glucose levels). RESULTS: There were 132 patients with HZ in the study period. The mean age of patients was 52.98 +/- 18.91 years (range, 14 to 96) and 53% (70 patients) were male. Of the study patients, 70.5% (93 patients) were over 45 years old. Eight (6.1%) patients had been diagnosed to have a malignancy, 18 (13.6%) had diabetes mellitus and 3 (2.3%) patients had undergone organ transplantation during their admission. Malignancy, diabetes mellitus and organ transplantation prevalence in the HZ group was significantly higher than the whole Emergency Department population. CONCLUSIONS: Our results indicate a relationship between the presence of HZ and increasing age and cell-mediated immunosuppressive disorders in Emergency Department patients over the age of 45 years. HZ should be considered as a clinical marker of cell-mediated immunosuppressive disorders, particularly in elderly patients.


Asunto(s)
Herpes Zóster/inmunología , Tolerancia Inmunológica/inmunología , Inmunidad Celular/inmunología , Trastornos Linfoproliferativos/complicaciones , Subgrupos de Linfocitos T/inmunología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Diagnóstico Diferencial , Femenino , Estudios de Seguimiento , Herpes Zóster/epidemiología , Herpes Zóster/etiología , Humanos , Inmunosupresores/efectos adversos , Inmunosupresores/uso terapéutico , Incidencia , Trastornos Linfoproliferativos/tratamiento farmacológico , Trastornos Linfoproliferativos/inmunología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Riesgo , Singapur/epidemiología , Adulto Joven
2.
Clin Toxicol (Phila) ; 45(3): 299-300, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17453886

RESUMEN

Abamectin is a potent antihelmintic, insecticide, and miticide used to control pests of humans, veterinary animals, and crops. The toxic effects of abamectin are usually seen after oral ingestions. These are altered mental status, respiratory failure, and hypotension. We report a case of acute abamectin intoxication who presented with altered mental status to the emergency department after oral ingestion.


Asunto(s)
Antihelmínticos/envenenamiento , Coma/inducido químicamente , Hipotensión/inducido químicamente , Ivermectina/análogos & derivados , Administración Oral , Adulto , Antídotos/uso terapéutico , Presión Sanguínea/efectos de los fármacos , Presión Sanguínea/fisiología , Carbón Orgánico/uso terapéutico , Trastornos del Conocimiento/inducido químicamente , Coma/fisiopatología , Servicio de Urgencia en Hospital , Femenino , Humanos , Hipotensión/fisiopatología , Unidades de Cuidados Intensivos , Ivermectina/envenenamiento , Intoxicación/diagnóstico , Intoxicación/fisiopatología , Intoxicación/terapia , Resultado del Tratamiento
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