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Molecules ; 26(16)2021 Aug 09.
Article En | MEDLINE | ID: mdl-34443400

The search for coatings that extend the useful life of biomedical devices has been of great interest, and titanium has been of great relevance due to its innocuousness and low reactivity. This study contributes to the investigation of Ti/Ag films in different configurations (monolayer and multilayer) deposited by magnetron sputtering. The sessile droplet technique was applied to study wettability; greater film penetrability was obtained when Ag is the external layer, conferring high efficiency in cell adhesion. The morphological properties were characterized by SEM, which showed porous nuclei on the surface in the Ag coating and crystals embedded in the Ti film. The structural properties were studied by XRD, revealing the presence of TiO2 in the anatase crystalline phase in a proportion of 49.9% and the formation of a silver cubic network centered on the faces. Tafel polarization curves demonstrated improvements in the corrosion current densities of Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti and Ti/Ag compared to the Ag coating, with values of 0.1749, 0.4802, and 2.044 nA.m-2, respectively. Antimicrobial activity was evaluated against the bacteria Pseudomonas aeruginosa and Bacillus subtilis and the yeasts Candida krusei and Candida albicans, revealing that the Ti/Ag and Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti coatings exhibit promise in biomedical material applications.


Coated Materials, Biocompatible/chemistry , Silver/pharmacology , Titanium/pharmacology , Wettability/drug effects , Anti-Infective Agents/chemistry , Anti-Infective Agents/pharmacology , Bacillus subtilis/drug effects , Bacillus subtilis/pathogenicity , Candida/drug effects , Candida/pathogenicity , Coated Materials, Biocompatible/pharmacology , Humans , Materials Testing , Pichia/drug effects , Pichia/pathogenicity , Pseudomonas aeruginosa/drug effects , Pseudomonas aeruginosa/pathogenicity , Silver/chemistry , Surface Properties , Titanium/chemistry
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