Case report: Hepatitis A preceding Guillain-Barré syndrome.

A case of acute hepatitis A with Guillain-Barré Syndrome subtype AMAN (acute motor axonal neuropathy) in a 17-year-old male is reported. Serum and cerebrospinal fluid were positive for anti-hepatitis A virus (HAV) IgM, IgG, and IgA. The onset of the syndrome was evident in week 3 of illness. The remarkably high titers of serum anti-HAV IgG appeared unique to a hepatitis A patient with the syndrome. Phylogenetic analysis of the HAV genome detected in the serum and feces revealed genotype IIIA, circulating commonly in Pune, western India.

Pemphigus erythematosus and thymoma.

A sixty year old woman was found to have a benign thymoma and pemphigus erythematosus. Her skin disease was controlled with oral and topical corticosteroids. The association between thymoma and pemphigus erythematosus is discussed, and the literature reviewed. Most previous cases have also had myasthenia gravis and skeletal muscle antibodies. This is the first case in which neither of these was present.

Familial primary cutaneous amyloidosis. Clinical, genetic, and immunofluorescent studies.

Familial primary cutaneous amyloidosis, a rare, autosomal dominant genodermatosis, affected 16 of 46 family members of German descent. Previous case reports involved families of Russian, Spanish, or Chinese descent. The finding of IgG, IgM, C3 in the amyloid deposits confirms recent reports of immunofluorescent dermal amyloid deposits.