RESUMEN
The authors describe the surgical technique used to obtain (by anterior and posterior access) autoplastic bone from the ilium in 186 oncological cases. Indications, the results obtained and the principal causes of complications are discussed.
Asunto(s)
Trasplante Óseo/métodos , Ilion/trasplante , Complicaciones Posoperatorias/epidemiología , Neoplasias Óseas/complicaciones , Neoplasias Óseas/cirugía , Trasplante Óseo/efectos adversos , Humanos , Complicaciones Posoperatorias/etiología , Trasplante AutólogoRESUMEN
This report deals with endemic chronic arsenical intoxication (HACRE) observed in several provinces in Argentina. Similar reports come from Chili, Mexico, Brasil, Bolivia, Peru and Japan. HACRE patients show no systemic, symptoms and specific manifestations are palmoplantar keratoderma, multiple cutaneous epitheliomas, mainly Bowen-type and respiratory or digestive carcinomas. The authors emphasize that these specific manifestations of HACRE are worth knowing for their possible social incidence.
Asunto(s)
Intoxicación por Arsénico , Queratodermia Palmoplantar/inducido químicamente , Neoplasias Cutáneas/inducido químicamente , Contaminantes Químicos del Agua/envenenamiento , Contaminantes del Agua/envenenamiento , Adolescente , Adulto , Anciano , Argentina , Niño , Preescolar , Diagnóstico Diferencial , Neoplasias del Sistema Digestivo/inducido químicamente , Femenino , Humanos , Lactante , Recién Nacido , Japón , Queratodermia Palmoplantar/patología , América Latina , Leucoplasia Bucal/inducido químicamente , Masculino , Persona de Mediana Edad , Enfermedades del Sistema Nervioso/inducido químicamente , Neoplasias del Sistema Respiratorio/inducido químicamente , Enfermedades de la Piel/diagnóstico , Neoplasias Cutáneas/patología , Agrupamiento Espacio-TemporalRESUMEN
From 1972 to October 1982 we have observed 39 cases of mycetoma in the Skin Department of the Hospital del Milagro, Salta (Argentina). The diagnosis was based on the clinical aspect, mycological studies and in most cases histopathology was done as well. The mayoritary of the patients were farmers. From the clinical point of view there si a true prevalence of Nocardia Brasiliensis. Most of the mycetomas can be found in the lower limbs. Some of the patients presented quite severe lesions and eight of them had bone involvement. The combination of long action sulphas with sulphonas has been efficient enough in the treatment of mycetomas caused by Nocardia Brasiliensis.
Asunto(s)
Micetoma/epidemiología , Nocardiosis/epidemiología , Actinomycetaceae/aislamiento & purificación , Adulto , Anciano , Argentina , Dapsona/uso terapéutico , Combinación de Medicamentos/uso terapéutico , Quimioterapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Hongos Mitospóricos/aislamiento & purificación , Micetoma/tratamiento farmacológico , Micetoma/microbiología , Nocardia/aislamiento & purificación , Nocardiosis/tratamiento farmacológico , Sulfametoxazol/uso terapéutico , Trimetoprim/uso terapéutico , Combinación Trimetoprim y SulfametoxazolRESUMEN
Arsenical pollution of water supplies is a chronic problem of great medical, social and sanitary importance in Argentina. The well-known cutaneous manifestations of chronic arsenical toxicity, palmar and plantar keratoses, melanoderma and multiple epitheliomas are described. The interest which this disease has evoked in the last few years is emphasized when new arsenical areas are discovered with clinical cases of chronic arsenical intoxication. Furthermore it is shown that the high content of arsenic in drinking water may be the determining factor in the incidence of visceral neoplasms. Contrary to classic beliefs, the chronic toxic effects from arsenic may be present in young children but the palmar and plantar keratoses may be absent. The histochemical localization of the arsenic in the skin and its relation to thyroid function and the production of leukoplakia and laryngeal cancer are noted. When one analyses all the recent reports it is evident that patients with chronic arsenical intoxication must now be thoroughly studied bearing in mind the multiple localization of this carcinogenic agent.