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1.
Pain Med ; 24(Suppl 1): S160-S174, 2023 08 04.
Artículo en Inglés | MEDLINE | ID: mdl-36799544

RESUMEN

Chronic low back pain (cLBP) is a prevalent and multifactorial ailment. No single treatment has been shown to dramatically improve outcomes for all cLBP patients, and current techniques of linking a patient with their most effective treatment lack validation. It has long been recognized that spinal pathology alters motion. Therefore, one potential method to identify optimal treatments is to evaluate patient movement patterns (ie, motion-based phenotypes). Biomechanists, physical therapists, and surgeons each utilize a variety of tools and techniques to qualitatively assess movement as a critical element in their treatment paradigms. However, objectively characterizing and communicating this information is challenging due to the lack of economical, objective, and accurate clinical tools. In response to that need, we have developed a wearable array of nanocomposite stretch sensors that accurately capture the lumbar spinal kinematics, the SPINE Sense System. Data collected from this device are used to identify movement-based phenotypes and analyze correlations between spinal kinematics and patient-reported outcomes. The purpose of this paper is twofold: first, to describe the design and validity of the SPINE Sense System; and second, to describe the protocol and data analysis toward the application of this equipment to enhance understanding of the relationship between spinal movement patterns and patient metrics, which will facilitate the identification of optimal treatment paradigms for cLBP.


Asunto(s)
Dolor Crónico , Dolor de la Región Lumbar , Vértebras Lumbares , Captura de Movimiento , Dispositivos Electrónicos Vestibles , Dolor de la Región Lumbar/diagnóstico , Dolor de la Región Lumbar/fisiopatología , Dolor Crónico/diagnóstico , Dolor Crónico/fisiopatología , Técnicas Biosensibles , Humanos , Captura de Movimiento/instrumentación , Captura de Movimiento/métodos , Fenómenos Biomecánicos , Vértebras Lumbares/fisiopatología , Fenotipo , Masculino , Femenino , Adolescente , Adulto Joven , Adulto , Nanocompuestos
2.
Sci Robot ; 5(39)2020 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-33022603

RESUMEN

Compliant sensors based on composite materials are necessary components for geometrically complex systems such as wearable devices or soft robots. Composite materials consisting of polymer matrices and conductive fillers have facilitated the manufacture of compliant sensors due to their potential to be scaled in printing processes. Printing composite materials generally entails the use of solvents, such as toluene or cyclohexane, to dissolve the polymer resin and thin down the material to a printable viscosity. However, such solvents cause swelling and decomposition of most polymer substrates, limiting the utility of the composite materials. Moreover, many such conventional solvents are toxic or otherwise present health hazards. Here, sustainable manufacturing of sensors is reported, which uses an ethanol-based Pickering emulsion that spontaneously coagulates and forms a conductive composite. The Pickering emulsion consists of emulsified polymer precursors stabilized by conductive nanoparticles in an ethanol carrier. Upon evaporation of the ethanol, the precursors are released, which then coalesce amid nanoparticle networks and spontaneously polymerize in contact with the atmospheric moisture. We printed the self-coagulating conductive Pickering emulsion onto a variety of soft polymeric systems, including all-soft actuators and conventional textiles, to sensitize these systems. The resulting compliant sensors exhibit high strain sensitivity with negligible hysteresis, making them suitable for wearable and robotic applications.


Asunto(s)
Robótica/instrumentación , Dispositivos Electrónicos Vestibles , Materiales Biomiméticos , Adaptabilidad , Conductividad Eléctrica , Emulsiones , Diseño de Equipo , Etanol , Humanos , Nanopartículas , Polímeros , Solventes , Textiles
3.
Proc Natl Acad Sci U S A ; 117(41): 25360-25369, 2020 10 13.
Artículo en Inglés | MEDLINE | ID: mdl-32989123

RESUMEN

Fabrics are ubiquitous materials that have conventionally been passive assemblies of interlacing, inactive fibers. However, the recent emergence of active fibers with actuation, sensing, and structural capabilities provides the opportunity to impart robotic function into fabric substrates. Here we present an implementation of robotic fabrics by integrating functional fibers into conventional fabrics using typical textile manufacturing techniques. We introduce a set of actuating and variable-stiffness fibers, as well as printable in-fabric sensors, which allows for robotic closed-loop control of everyday fabrics while remaining lightweight and maintaining breathability. Finally, we demonstrate the utility of robotic fabrics through their application to an active wearable tourniquet, a transforming and load-bearing deployable structure, and an untethered, self-stowing airfoil.

4.
Soft Matter ; 16(25): 5827-5839, 2020 Jul 07.
Artículo en Inglés | MEDLINE | ID: mdl-32347290

RESUMEN

Many soft robotic components require highly stretchable, electrically conductive materials for proper operation. Often these conductive materials are used as sensors or as heaters for thermally responsive materials. However, there is a scarcity of stretchable materials that can withstand the high strains typically experienced by soft robots, while maintaining the electrical properties necessary for Joule heating (e.g., uniform conductivity). In this work, we present a silicone composite containing both liquid and solid inclusions that can maintain a uniform conductivity while experiencing 200% linear strains. This composite can be cast in thin sheets enabling it to be wrapped around thermally responsive soft materials that increase their volume or stretchability when heated. We show how this material opens up possibilities for electrically controllable shape changing soft robotic actuators, as well as all-silicone actuation systems powered only by electrical stimulus. Additionally, we show that this stretchable composite can be used as an electrode material in other applications, including a strain sensor with a linear response up to 200% strain and near-zero signal noise.

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