BACKGROUND: Oncological outcomes of self-expanding metallic stent used as a bridge to surgery in potential curative patients with left-sided colonic cancer obstruction remain unclear. The aim of this study was to investigate perioperative and mid-term oncological outcomes of 2 of the currently most commonly performed treatments in left-sided colonic cancer obstruction. METHODS: This is a retrospective multicenter study including patients with left-sided colonic cancer obstruction treated with curative intent between 2013 and 2017. The presence of metastasis at diagnosis was an exclusion criterion. The primary outcome was to evaluate the noninferiority, in terms of overall survival, of bridge to surgery strategy compared with emergency colonic resection. The secondary outcomes were perioperative morbimortality, disease free survival, local recurrence, and distant recurrence. RESULTS: A total of 564 patients were included, 320 in the emergency colonic resection group and 244 in the bridge to surgery group. Twenty-seven patients of the bridge-to-surgery group needed urgent operation. Postoperative morbidity rates were statistically higher in the emergency colonic resection group (odds ratio [95% confidence interval] 0.37 [0.24-0.55], P < .001). There was no difference in 90-day mortality between groups (odds ratio [95% confidence interval] 0.85 [0.36-1.99], P = .702). The median follow-up was 3.80 years (2.29-4.92). The results show the noninferiority of bridge to surgery versus emergency colonic resection in terms of overall survival (hazard ratio [95% confidence interval) 0.78 [0.56-1.07], P = .127). There were no differences in disease free survival, distant recurrence, and local recurrence rates between bridge to surgery and emergency colonic resection groups. CONCLUSION: Self-expanding metallic stent as bridge to surgery might not lead to a negative impact on the long-term prognosis of the tumor compared with emergency colonic resection in expert hands and selected patients.
Colonic Neoplasms , Colorectal Neoplasms , Intestinal Obstruction , Colonic Neoplasms/complications , Colonic Neoplasms/pathology , Colonic Neoplasms/surgery , Colorectal Neoplasms/surgery , Disease-Free Survival , Humans , Intestinal Obstruction/complications , Intestinal Obstruction/surgery , Retrospective Studies , Stents , Treatment Outcome
La hernia de Amyand tiene baja incidencia (0,1 a 1 %) pero, en caso de complicación, puede asociarse con una alta tasa de mortalidad. A pesar de haber sido descrita hace más de 200 años por Claudius Amyand, siguen existiendo ciertas controversias sobre su correcto tratamiento en determinadas situaciones. La práctica o la evitación de la apendicectomía en ausencia de apendicitis y la técnica para reparar el defecto herniario según el grado de contaminación de la zona, son temas tratados en el presente artículo. Ante la falta de consenso global en la literatura científica, la individualización de cada caso y el buen juicio del cirujano deben primar a la hora de decidir el tratamiento más adecuado. Se presentan dos casos clínicos que, a pesar de tratarse de la misma enfermedad, tuvieron formas de presentación, manejo y evolución dispares. Asimismo, se adjunta la iconografía de un excepcional caso de hernia de Amyand, izquierda, junto con el hallazgo de una hernia de Littré no complicada en el mismo saco herniario
Amyand's hernia has a low incidence (0.1%-1.0%) but it may be associated with high mortality rates. Despite having been described more than 200 years ago by Claudius Amyand, there are still controversies regarding treatment in some particular situations. Performing or not appendectomies in the absence of appendicitis, or how to perform the hernia repair depending on the degree of contamination, are topics discussed in this article. There is not a global consensus in the literature yet. The individualization of each case and the surgeon´s proper judgment should be the priority for selecting the most appropriate treatment. Two clinical cases of Amyand's hernia are reported with very different clinical presentations, management and evolution. Also, an image of a left sided Amyand's hernia together with a Littre's hernia in the same hernia sac is shown
Humans , Hernia, Inguinal , Appendectomy , Herniorrhaphy , Prostheses and Implants
