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1.
J Am Coll Health ; : 1-9, 2024 Apr 09.
Artículo en Inglés | MEDLINE | ID: mdl-38592936

RESUMEN

OBJECTIVES: Research increasingly focuses on the mental health implications of both actual and perceived weight, particularly among post-secondary students. Considering their unique socio-cultural context and the frequent oversight in research, this study examines these implications specifically among Canadian Indigenous post-secondary students. Recent evidence indicates that students with normal weight may also experience increased mental health risks due to negative weight perceptions. Therefore, this study explores the independent and combined effects of actual and perceived weight on the mental health of this group. PARTICIPANTS AND METHODS: This study utilized data from the 2017 Aboriginal Peoples Survey, a nationally representative sample of First Nations peoples living off-reserve, Métis, and Inuit. The focus was on Canadian Indigenous post-secondary students aged 19-34 years (n = 1,518). Logistic regression models, stratified by sex, were employed to analyze the data. RESULTS: Perceptions of being overweight were linked to a higher risk of mood and anxiety disorders, poor self-rated mental health, and suicidal ideation among female students. This pattern was less evident among male students. Notably, female students who were overweight and perceived themselves as such were more likely to report poor mental health across all four indicators examined. In contrast, male students exhibited a less clear pattern. Diverging from recent studies, the findings indicated less robust mental health disparities among students with normal weight who perceived themselves as overweight, potentially due to the insufficient cell size of this category among Indigenous post-secondary students. CONCLUSIONS: The study highlights the complex interplay between actual and perceived weight and its impact on mental health, particularly among female Indigenous post-secondary students.

2.
Adv Sci (Weinh) ; 11(23): e2308939, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38600650

RESUMEN

Lithium metal, with ultrahigh theoretical specific capacity, is considered as an ideal anode material for the lithium-ion batteries. However, its practical application is severely plagued by the uncontrolled formation of dendritic Li. Here, a cation-loaded porous Mg2+-Zeolite layer is proposed to enable the dendrite-free deposition on the surface of Li metal anode. The skeleton channels of zeolite provide the low coordinated Li+-solvation groups, leading to the faster desolvation process at the interface. Meanwhile, anions-involved solvation sheath induces a stable, inorganic-rich SEI, contributing to the uniform Li+ flux through the interface. Furthermore, the co-deposition of sustained release Mg2+ realizes a new faster migration pathway, which proactively facilitates the uniform diffusion of Li on the lithium substrate. The synergistic modulation of these kinetic processes facilitates the homogeneous Li plating/stripping behavior. Based on this synergistic mechanism, the high-efficiency deposition with cyclic longevity exceeding 2100 h is observed in the symmetric Li/Li cell with Mg2+-Zeolite modified anode at 1 mA cm-2. The pouch cell matched with LiFePO4 cathode fulfills a capacity retention of 88.4% after 100 cycles at a severe current density of 1 C charge/discharge. This synergistic protective mechanism can give new guidance for realizing the safe and high-performance Li metal batteries.

3.
Am J Health Promot ; : 8901171241246842, 2024 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-38621955

RESUMEN

PURPOSE: While the individual impacts of long-term residence and food insecurity on overweight/obesity are well-documented, their combined effect on immigrants' weight status is less understood. This study examines the interaction between length of residence and food insecurity in predicting overweight/obesity among immigrants and investigates whether this relationship is gender-specific. DESIGN: A national cross-sectional survey. SETTING: The 2017-2018 Canadian Community Health Survey. SUBJECTS: Immigrants aged 18 and older (N = 13 680). MEASURES: All focal variables were self-reported. ANALYSIS: Logistic regression models were employed. RESULTS: Long-term immigrants were more likely to report overweight/obesity than their short-term counterparts (OR = 1.39; P < .001). Moreover, immigrants from food-insecure households were at a higher risk of reporting overweight/obesity (OR = 1.27; P < .05) compared to those from food-secure households. The analysis further revealed that food insecurity exacerbated the detrimental association between length of residence and overweight/obesity in men (OR = 2.63; P < .01) but not in women (OR = .66; P > .05). CONCLUSION: The findings suggest that long-term immigrant men may be especially susceptible to the compounded chronic stressors of extended residence and food insecurity. Health professionals and policymakers should advocate for psychosocial resources to help mitigate these adverse effects and support the well-being of immigrant populations.

4.
J Gerontol Soc Work ; 67(4): 474-491, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38466950

RESUMEN

This study examined the moderating role of perceived community belonging in the relationship between childhood abuse and health and well-being outcomes among Canadian individuals aged 55 and older. Using data from the 2014 Canadian General Social Survey (n = 14,416), multiple linear regression models revealed that women who experienced either childhood physical or sexual abuse reported poorer self-rated general and mental health, as well as lower life satisfaction, compared to those without such histories. The most pronounced effects were observed among women who experienced both types of abuse. For men, a similar pattern was evident only for those who experienced childhood physical abuse. Notably, among women, a strong sense of community belonging lessened the negative effects of both types of childhood abuse on all examined outcomes. These findings underscore the protective role of perceived community belonging against the consequences of childhood abuse for older women. They illuminate the crucial role of gerontological social workers and scholars in promoting community integration and support. Focusing on these areas, especially for those with traumatic histories, can potentially improve their overall health and well-being.


Asunto(s)
Estado de Salud , Pueblos de América del Norte , Humanos , Femenino , Masculino , Anciano , Canadá/epidemiología , Persona de Mediana Edad , Maltrato a los Niños/psicología , Encuestas y Cuestionarios , Anciano de 80 o más Años , Salud Mental , Adultos Sobrevivientes del Maltrato a los Niños/psicología , Percepción
5.
Ethn Health ; 29(3): 371-394, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38297918

RESUMEN

OBJECTIVES: Despite growing interest in the health disparities associated with food insecurity, research focusing on Indigenous peoples has been limited, especially in studies using nationally representative samples. This study investigates the association between food insecurity and various health outcomes - self-rated general and mental health, chronic health conditions, suicidal ideation, and obesity - among Indigenous peoples in Canada. It also explores the potential moderating effects of culture-based resources, which include cultural identity affect, cultural group belonging, cultural engagement, and cultural exploration. DESIGN: The study utilized data from the 2017 Aboriginal Peoples Survey, a nationally representative sample of First Nations individuals living off-reserve, Métis, and Inuit across Canada (N = 15,533). Logistic regression models were used to analyze the data. RESULTS: Food insecurity was negatively associated with all examined health outcomes. Culture-based resources demonstrated a mixture of anticipated and unexpected effects on these relationships. Consistent with the stress process model, cultural group belonging mitigated the negative impact of food insecurity on all health outcomes. A similar pattern was observed for cultural engagement. However, contrary to expectations from the stress-buffering perspective, little evidence was found to support the moderating effects of cultural identity affect and cultural exploration. CONCLUSION: The results underscore the detrimental effects of food insecurity on the health of Indigenous peoples in Canada and suggest that culture-based resources, particularly cultural group belonging, play a crucial role in mitigating health disparities.


Asunto(s)
Inseguridad Alimentaria , Pueblos Indígenas , Humanos , Factores Socioeconómicos , Encuestas y Cuestionarios , Evaluación de Resultado en la Atención de Salud , Canadá/epidemiología
6.
Biol Trace Elem Res ; 2024 Jan 20.
Artículo en Inglés | MEDLINE | ID: mdl-38244175

RESUMEN

Fluorosis decreases the learning and memory ability in humans and animals, while exercise can reduce the risk of cognitive decline. However, the effect of exercise on learning and memory in fluoride-exposed mice is unclear. For this purpose, in this study, mice were randomly allotted into four groups (16 mice per group, half male and half female): control group (group C), fluoride group (group F, 100 mg/L sodium fluoride (NaF)), exercise group (group E, treadmill exercise), and E plus F group (group EF, treadmill exercise, and 100 mg/L NaF). During 6 months of exposure, exercise alleviated the NaF-induced decline in memory and learning. In addition, NaF induced injuries in mitochondria and myelin sheath ultrastructure and reduced the neurons number, while exercise restored them. Metabolomics results showed that phosphatidylethanolamine, pregnenolone (PREG), and lysophosphatidic acid (LysoPA) were altered among groups C, F, and EF. Combined with previous studies, it can be suggested that PREG might be a biomarker in response to exercise-relieving fluorine neurotoxicity. The miRNA sequencing results indicated that in the differently expressed miRNAs (DEmiRNAs), miR-206-3p, miR-96-5p, and miR-144-3p were shared in groups C, F, and EF. After the QRT-PCR validation and in vitro experiments, it was proved that miR-206-3p could reduce cell death and regulate AP-1 transcription factor subunit (JunD) and histone deacetylase 4 (HDAC4) to alleviate fluoride neurotoxicity. To sum up, the current study reveals that exercise could alleviate NaF-induced neurotoxicity by targeting miR-206-3p or PREG, which will contribute to revealing the pathogenesis and therapeutic method of fluoride neurotoxicity.

7.
Am J Health Promot ; 38(3): 325-338, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-37789687

RESUMEN

PURPOSE: This study examines the moderating role of perceived community belonging in the association between sexual orientation and various health and well-being outcomes. DESIGN: A national cross-sectional survey. SETTING: Confidential microdata from the 2021 Canadian Community Health Survey. SUBJECTS: Individuals aged 15 and older, with a sample size ranging from 43,000 to 44,100. MEASURES: Sexual orientation, health and well-being outcomes, and sense of community belonging were all self-reported. Outcomes included self-rated general and mental health, depressive symptoms, and life satisfaction. ANALYSIS: A series of multiple linear regression models. RESULTS: Compared to heterosexual individuals, bisexual individuals reported poorer self-rated general health (b = .402, P < .001 for men; b = .454, P < .001 for women) and mental health (b = .520, P < .001 for men; b = .643, P < .001 for women), higher depressive symptoms (b = 2.140, P < .001 for men; b = 2.685, P < .001 for women), and lower life satisfaction (b = .383, P < .05 for men; b = .842, P < .001 for women). Few disparities were observed among gay men and lesbians. Contrary to some recent findings, no disparities were observed among individuals uncertain about their sexual orientation or those who chose not to disclose it, even without controlling for covariates. A stronger sense of community belonging mitigated the disadvantages associated with self-rated general health (b = -.276, P < .01) and depressive symptoms (b = -.983, P < .01) for gay men, and life satisfaction (b = -.621, P < .01) for lesbians. CONCLUSION: This study is among the first to highlight the stress-buffering role of community belonging in the association between sexual orientation and health and well-being outcomes.


Asunto(s)
Homosexualidad Femenina , Minorías Sexuales y de Género , Humanos , Femenino , Masculino , Estudios Transversales , Canadá/epidemiología , Conducta Sexual
8.
Artículo en Inglés | MEDLINE | ID: mdl-37907713

RESUMEN

PURPOSE: Despite a growing body of literature on the link between residential mobility and suicidal ideation, research into potential mediating or moderating factors, especially among socioeconomically disadvantaged populations, is sparse. This study explores the mediating and moderating roles of food insecurity in the relationship between residential mobility and suicidal ideation in Indigenous Canadian adults. METHODS: Data from the 2017 Aboriginal Peoples Survey, which represent a national sample of off-reserve First Nations peoples, Métis, and Inuit in Canada (N = 16,214), were analyzed using logistic regression models. RESULTS: Food insecurity partially mediated the association between residential mobility in the past 5 years and increased suicidal ideation risk among Indigenous adults. Moreover, food insecurity intensified the adverse link between residential mobility during this same timeframe and suicidal ideation. Yet, while food insecurity did mediate the adverse relationship between residential mobility in the past year and suicidal ideation, it did not function as a moderator. CONCLUSION: The results emphasize that food insecurity, as a systemic challenge, acts as both a partial mediator and, in some circumstances, an amplifier of the detrimental impacts of residential mobility on suicidal ideation.

9.
Fam Community Health ; 46(4): 242-249, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37703512

RESUMEN

Existing research has established the detrimental effects of food insecurity on health. However, understanding of the social conditions that may moderate this relationship remains limited. To address this gap, the study investigates two questions: First, does marital status moderate the association between food insecurity and self-rated health? Second, if such moderation exists, does its impact vary based on gender? Data from the 2017-2018 Canadian Community Health Survey, a nationally representative survey conducted by Statistics Canada (n =101 647), were utilized for this investigation. The findings demonstrated that individuals living in food-insecure households reported poorer self-rated mental and general health. However, the negative impact of food insecurity on both health outcomes was less pronounced among married individuals than among their unmarried counterparts. Furthermore, the stress-buffering role of marriage was found to be more substantial among men than among women. In light of the significant stress-buffering role of marriage revealed in this study, it is crucial for policies to aim at providing comparable coping resources to unmarried individuals, particularly women.


Asunto(s)
Composición Familiar , Abastecimiento de Alimentos , Masculino , Humanos , Femenino , Canadá , Estado Civil , Inseguridad Alimentaria
10.
Environ Pollut ; 337: 122640, 2023 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-37769704

RESUMEN

Soil contamination is a major environmental issue worldwide. Compared with Arctic, European Alps and Rocky Mountains, the soil contamination and soil environment carrying capacity (SECC) of the Tibetan Plateau (TP) is not systematic and multidimensional. In this study, the levels, influencing factors including climate factors [(i.e., mean annual precipitation (MAP) and mean annual temperature (MAT)], socio-economic factors [(i.e., population, population density and gross domestic product (GDP)], vegetation coverage factor, soil factors [(i.e., pH, soil organic carbon (SOC), total phosphorus and total nitrogen] and topographic factors [(i.e., longitude, latitude and digital elevation model (DEM)] and carrying capacity of multiple soil contaminants [persistent organic pollutants (POPs), heavy metals (HMs) and microplastics (MPs)] was systematically studied. Results show that the spatial distribution of POPs in the eastern was higher than that in the western region, and the structural equation model (SEM) demonstrate that SOC and MAT were the key factors influencing distribution. Regarding HMs, except As, moderate and heavy pollution of the remaining elements were found in the northern and eastern TP regions, and pH and MAP were the main influencing factors. The MPs showed that the distribution of the patches was influenced by GDP and MAP. Furthermore, a higher SECC in the eastern region that gradually decreased from east to west. pH is the primary factors affecting SECC, followed by normalized difference vegetation index (NDVI). An increase of pH and NDVI by one unit is likely to make SECC scores decrease by 0.8 and increase by 0.32, respectively. Taken together, these studies provide a system, cost-effective, and quantitative framework for soil contamination and carrying capacity in the TP.


Asunto(s)
Metales Pesados , Suelo , Suelo/química , Tibet , Conservación de los Recursos Naturales , Carbono , Plásticos
11.
J Gerontol Soc Work ; 66(8): 1120-1132, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37139587

RESUMEN

This study investigates the association between financial strain and psychological distress among middle-aged and older adults, exploring how this association is mediated by sleep problems and moderated by marital status. A subsample of 12,095 adults aged 50 and older was selected from the 2018 National Health Interview Survey. Results showed that financial strain was associated with higher psychological distress, and sleep problems partially mediated this association. Marital status moderated the association between sleep problems and psychological distress, and between financial strain and psychological distress, but not between financial strain and sleep problems. These findings partially support the stress-buffering role of marriage. The study offers valuable insights into the complex relationship between financial strain, sleep problems, marital status, and psychological distress among middle-aged and older adults in the United States, highlighting the need for interventions targeting financial stressors and sleep problems, especially for unmarried individuals, to improve mental health outcomes in this population.


Asunto(s)
Distrés Psicológico , Trastornos del Sueño-Vigilia , Humanos , Estados Unidos/epidemiología , Persona de Mediana Edad , Anciano , Encuestas y Cuestionarios , Trastornos del Sueño-Vigilia/complicaciones , Trastornos del Sueño-Vigilia/epidemiología , Estrés Psicológico/complicaciones , Estrés Psicológico/psicología
12.
Arch Suicide Res ; : 1-19, 2023 Apr 13.
Artículo en Inglés | MEDLINE | ID: mdl-37052051

RESUMEN

OBJECTIVES: The present study asks: Is disability is associated with suicidal ideation among Indigenous adults in Canada? And if so, do cultural resources-as measured by cultural identity affect, cultural group belonging, cultural engagement, and cultural exploration-modify this association? METHODS: Data were from a nationally representative sample of First Nations peoples living off-reserve, Métis, and Inuit across Canada-the 2017 Aboriginal Peoples Survey (N = 16,125). A series of weighted logistic regression models were performed. RESULTS: Indigenous adults with disabilities were significantly more likely than those without disabilities to report suicidal ideation, even after controlling for socio-demographic characteristics and physical and mental health conditions. At the same time, people with multiple disabilities were at greater risk for suicidal ideation, with the largest association among those with five or more disabilities. Furthermore, the detrimental association between disability status and suicidal ideation attenuated among those who reported cultural group belonging. In a similar vein, the buffering role of cultural group belonging was also observed in the association between the number of disabilities and suicidal ideation. CONCLUSIONS: This study provides compelling evidence that disability is a risk factor for suicidal ideation among Indigenous adults and that cultural group belonging plays a stress-buffering role in this relationship.

13.
J Digit Imaging ; 36(4): 1910-1918, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-37039950

RESUMEN

It is difficult to accurately understand the angioarchitecture of cerebral arteriovenous malformations (CAVMs) before surgery using existing imaging methods. This study aimed to evaluate the ability of the stereoscopic virtual reality display system (SVRDS) to display the angioarchitecture of CAVMs by comparing its accuracy with that of the conventional computed tomography workstation (CCTW). Nineteen patients with CAVM confirmed on digital subtraction angiography (DSA) or during surgery were studied. Computed tomography angiography images in the SVRDS and CCTW were retrospectively analyzed by two experienced neuroradiologists using a double-blind method. Angioarchitectural parameters, such as the location and size of the nidus, type and number of the arterial feeders and draining veins, and draining pattern of the vessels, were recorded and compared. The diameter of the nidus ranged from 1.1 to 9 cm. Both CCTW and SVRDS correctly diagnosed the location of the nidus in 19 patients with CAVM. Among the 19 patients, 35 arterial feeders and 25 draining veins were confirmed on DSA and during surgery. With the DSA and intraoperative results as the gold standard bases, the CCTW misjudged one arterial feeder and one draining vein and missed three arterial feeders and two draining veins; meanwhile, the SVRDS missed only two arterial feeders. SVRDS had some advantages in displaying nidus, arterial branches, and draining veins of the CAVM compared with CCTW, as well as SVRDS could more intuitively display the overall angio-architectural spatial picture of CAVM.


Asunto(s)
Malformaciones Arteriovenosas Intracraneales , Realidad Virtual , Humanos , Estudios Retrospectivos , Malformaciones Arteriovenosas Intracraneales/diagnóstico por imagen , Malformaciones Arteriovenosas Intracraneales/cirugía , Angiografía Cerebral , Tomografía Computarizada por Rayos X/métodos , Angiografía de Substracción Digital
14.
Int J Nanomedicine ; 18: 1695-1708, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37020689

RESUMEN

Graphene-family nanomaterials (GFNs) possess mechanical stiffness, optical properties, and biocompatibility making them promising materials for biomedical applications. However, to realize the potential of graphene in biomedicine, it must overcome several challenges that arise when it enters the body's circulatory system. Current research focuses on the development of tumor-targeting devices using graphene, but GFNs accumulated in different tissues and cells through different pathways, which can cause toxic reactions leading to cell apoptosis and body dysfunction when the accumulated amount exceeds a certain limit. In addition, as a foreign substance, graphene can induce complex inflammatory reactions with immune cells and inflammatory factors, potentially enhancing or impairing the body's immune function. This review discusses the biomedical applications of graphene, the effects of graphene materials on human immune function, and the biotoxicity of graphene materials.


Asunto(s)
Grafito , Nanoestructuras , Humanos , Apoptosis
15.
Biol Trace Elem Res ; 201(12): 5734-5746, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36884125

RESUMEN

Hepatotoxicity induced by excessive fluoride (F) exposure has been extensively studied in both humans and animals. Chronic fluorosis can result in liver apoptosis. Meanwhile, moderate exercise alleviates apoptosis caused by pathological factors. However, the effect of moderate exercise on F-induced liver apoptosis remains unclear. In this research, sixty-four three-week-old Institute of Cancer Research (ICR) mice, half male and half female, were randomly divided into four groups: control group (distilled water); exercise group (distilled water and treadmill exercise); F group [100 mg/L sodium fluoride (NaF)]; and exercise plus F group (100 mg/L NaF and treadmill exercise). The liver tissues of mice were taken at 3 months and 6 months, respectively. Hematoxylin-eosin (HE) staining and situ terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) results showed that nuclear condensation and apoptotic hepatocytes occurred in the F group. However, this phenomenon could be reversed with the intervention of treadmill exercise. The results of QRT-PCR and western blot displayed NaF- induced apoptosis via tumor necrosis factor recpter 1 (TNFR1) signaling pathway, while treadmill exercise could restore the molecular changes caused by excessive NaF exposure.


Asunto(s)
Fluoruros , Hígado , Humanos , Ratones , Masculino , Femenino , Animales , Fluoruros/toxicidad , Fluoruros/metabolismo , Hígado/metabolismo , Apoptosis , Fluoruro de Sodio/toxicidad , Agua/metabolismo
16.
Child Abuse Negl ; 138: 106076, 2023 04.
Artículo en Inglés | MEDLINE | ID: mdl-36764172

RESUMEN

BACKGROUND: Considerable research has established the harmful impacts of the COVID-19 pandemic on children's and adolescents' health and well-being. However, the literature has been constrained by studies using less representative samples, hindering the generalization of the findings. OBJECTIVE: This study aimed to investigate the associations of employment disruption and school closures during the pandemic with suicidal ideation and behavior in children and adolescents-and to consider the potential mediating effects of child psychological and physical abuse and subsequent mental health conditions. PARTICIPANTS AND SETTING: This study used the Adolescent Behaviors and Experiences data (n = 4692) - a nationally representative survey administered by the CDC of the United States from January to June 2021. METHODS: Logistic regression models were conducted to investigate the associations. A series of multiple mediation models were performed. RESULTS: School closures directly reduced child psychological and physical abuse and suicidal ideation and behavior. Employment disruption did not directly predict suicidal ideation and behavior but primarily through child abuse. Mental health's mediation role was significant in the associations between child psychological abuse and suicidal ideation and behavior, but no evidence suggested the same mediating pattern for the physical abuse-suicidal ideation and behavior relationship. Within the covariates, sexual orientation was the most consistent and highest risk factor. CONCLUSIONS: This study contributes to current knowledge on disaster impact, child abuse, and suicidal ideation and behavior, and it can also provide policy and intervention awareness for social workers.


Asunto(s)
Conducta del Adolescente , COVID-19 , Maltrato a los Niños , Niño , Humanos , Masculino , Adolescente , Femenino , Estados Unidos/epidemiología , Intento de Suicidio/psicología , Salud Mental , Pandemias , COVID-19/epidemiología , Ideación Suicida , Maltrato a los Niños/psicología , Factores de Riesgo , Conducta del Adolescente/psicología
17.
J Immigr Minor Health ; 25(1): 38-49, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-35778538

RESUMEN

The present study examines (1) whether perceived life stress mediates the associations between length of residence in Canada and self-rated mental health and general health and (2) how these processes differ across levels of perceived local community belonging. Data are from the 2017-2018 Canadian Community Health Survey (N = 14,570)-a nationally representative survey collected by Statistics Canada. Simple mediation and moderated mediation models are employed. The simple mediated associations are evaluated first and found to be statistically significant for both self-rated mental health (b = 0.046, 95% PBCI = 0.035, 0.058) and general health (b = 0.045, 95% PBCI = 0.034, 0.056). Moderated mediation analysis then reveals that while perceived local community belonging does not moderate the effects of length of residence on perceived life stress, it does moderate the effects of perceived life stress on self-rated mental health (b = - 0.042, 95% PBCI = - 0.057, - 0.028) and general health (b = - 0.026, 95% PBCI = - 0.042, - 0.011), suggesting that the adverse associations between perceived life stress and self-rated mental health and general health are weaker among immigrants with greater perceived local community belonging. Consistent with the predictions, the indirect effects are significant at all levels of local community belonging. Findings from this study highlight the need to focus more research and policy interventions on community-based coping resources.


Asunto(s)
Emigrantes e Inmigrantes , Salud Mental , Humanos , Canadá/epidemiología , Encuestas y Cuestionarios , Encuestas Epidemiológicas
18.
J Digit Imaging ; 36(1): 114-123, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36085330

RESUMEN

The accuracy of computed tomography angiography (CTA) image interpretation depends on the radiologist. This study aims to develop a new method for automatically detecting intracranial aneurysms from CTA images using deep learning, based on a convolutional neural network (CNN) implemented on the DeepMedic platform. Ninety CTA scans of patients with intracranial aneurysms are collected and divided into two datasets: training (80 subjects) and test (10 subjects) datasets. Subsequently, a deep learning architecture with a three-dimensional (3D) CNN model is implemented on the DeepMedic platform for the automatic segmentation and detection of intracranial aneurysms from the CTA images. The samples in the training dataset are used to train the CNN model, and those in the test dataset are used to assess the performance of the established system. Sensitivity, positive predictive value (PPV), and false positives are evaluated. The overall sensitivity and PPV of this system for detecting intracranial aneurysms from CTA images are 92.3% and 100%, respectively, and the segmentation sensitivity is 92.3%. The performance of the system in the detection of intracranial aneurysms is closely related to their size. The detection sensitivity for small intracranial aneurysms (≤ 3 mm) is 66.7%, whereas the sensitivity of detection for large (> 10 mm) and medium-sized (3-10 mm) intracranial aneurysms is 100%. The deep learning architecture with a 3D CNN model on the DeepMedic platform can reliably segment and detect intracranial aneurysms from CTA images with high sensitivity.


Asunto(s)
Aprendizaje Profundo , Aneurisma Intracraneal , Humanos , Angiografía por Tomografía Computarizada , Tomografía Computarizada por Rayos X/métodos , Angiografía de Substracción Digital/métodos , Angiografía Cerebral/métodos , Sensibilidad y Especificidad
19.
Environ Sci Process Impacts ; 24(10): 1616-1630, 2022 Oct 19.
Artículo en Inglés | MEDLINE | ID: mdl-35770617

RESUMEN

Global warming profoundly affects not only mountainous and polar environments, but also the global and regional cycling of pollutants. Mercury (Hg) and persistent organic pollutants (POPs) have global transport capacity and are regulated by the Minamata Convention and Stockholm Convention, respectively. Since the beginning of this century, understanding of the origin and fate of Hg and POPs on the Tibetan Plateau (TP, also known as the third pole) has been deepening. In this paper, the existing literature is reviewed to comprehensively understand the atmospheric transport, atmospheric deposition, cumulative transformation and accumulation of Hg and POPs on the TP region under the background of global warming. The biogeochemical cycle of both Hg and POPs has the following environmental characteristics: (1) the Indian summer monsoon and westerly winds carry Hg and POPs inland to the TP; (2) the cold trapping effect causes Hg and POPs to be deposited on the TP by dry and wet deposition, making glaciers, permafrost, and snow the key sinks of Hg and POPs; (3) Hg and POPs can subsequently be released due to the melting of glaciers and permafrost; (4) bioaccumulation and biomagnification of Hg and POPs have been examined in the aquatic food chain; (5) ice cores and lake cores preserve the impacts of both regional emissions and glacial melting on Hg and POP migration. This implies that comprehensive models will be needed to evaluate the fate and toxicity of Hg and POPs on larger spatial and longer temporal scales to forecast their projected tendencies under diverse climate scenarios. Future policies and regulations should address the disrupted repercussions of inclusive CC such as weather extremes, floods and storms, and soil sustainable desertification on the fate of Hg and POPs. The present findings advocate the strengthening of the cross-national programs aimed at the elimination of Hg and POPs in polar (Arctic, Antarctic and TP) and certain mountainous (the Himalaya, Rocky Mountains, and Alps) ecosystems for better understanding the impacts of global warming on the accumulation of Hg/POPs in cold and remote areas.


Asunto(s)
Contaminantes Ambientales , Mercurio , Mercurio/análisis , Calentamiento Global , Contaminantes Orgánicos Persistentes , Monitoreo del Ambiente , Ecosistema , Tibet , Contaminantes Ambientales/análisis , Suelo
20.
J Fam Issues ; 43(6): 1555-1578, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35637740

RESUMEN

What is the relationship between work-to-family conflict (WFC) and children's problems with school, friends, and health? And does that association depend on household economic conditions and couple relationship quality? Using four waves of longitudinal data from the Canadian Work, Stress, and Heath Study (2011-2017), the present study finds that-overall-both fathers' and mothers' levels of WFC are associated with elevated levels of children's problems over time. However, we also discover that household income and spousal disputes moderate this focal relationship-and they do so differently for mothers and fathers. First, the positive association between WFC and children's problems is stronger for mothers (but not fathers) in households with lower income. Second, the positive association between WFC and children's problems is stronger for fathers (but not mothers) who report more frequent disputes with their spouse. We discuss the implications of these patterns for current theorizing about stress amplification dynamics and situate that discussion within broader ideas in the ecological model of human development.

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