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IEEE/ACM Trans Comput Biol Bioinform ; 20(4): 2565-2576, 2023.
Article En | MEDLINE | ID: mdl-35914053

In the area of medical image segmentation, the spatial information can be further used to enhance the image segmentation performance. And the 3D convolution is mainly used to better utilize the spatial information. However, how to better utilize the spatial information in the 2D convolution is still a challenging task. In this paper, we propose an image segmentation network based on reinforcement learning (RLSegNet), which can translate the image segmentation process into a serial of decision-making problem. The proposed RLSegNet is a U-shaped network, which is composed of three components: the feature extraction network, the Mask Prediction Network (MPNet), and the up-sampling network with the cascade attention module. The deep semantic feature in the image is first extracted by adopting the feature extraction network. Then, the Mask Prediction Network (MPNet) is proposed to generate the prediction mask for the current frame based on the prior knowledge (segmentation result). And the proposed cascade attention module is mainly used to generate the weighted feature mask so that the up-sampling network pays more attention to the interesting region. Specifically, the state, action and reward used in the reinforcement learning are redesigned in the proposed RLSegNet to translate the segmentation process as the decision-making process, which performs as the reinforcement learning to realize the brain tumor segmentation. Extensive experiments are conducted on the BRATS 2015 dataset to evaluate the proposed RLSegNet. The experimental results demonstrate that the proposed method can achieve a better segmentation performance, in comparison with other state-of-the-art methods.

2.
Med Image Anal ; 80: 102511, 2022 08.
Article En | MEDLINE | ID: mdl-35753278

Ultrasound-guided injection is widely used to help anesthesiologists perform anesthesia in peripheral nerve blockade (PNB). However, it is a daunting task to accurately identify nerve structure in ultrasound images even for the experienced anesthesiologists. In this paper, a Multi-object assistance based Brachial Plexus Segmentation Network, named MallesNet, is proposed to improve the nerve segmentation performance in ultrasound image with the assistance of simultaneously segmenting its surrounding anatomical structures (e.g., muscle, vein, and artery). The MallesNet is designed by following the framework of Mask R-CNN to implement the multi object identification and segmentation. Moreover, a spatial local contrast feature (SLCF) extraction module is proposed to compute contrast features at different scales to effectively obtain useful features for small objects. And the self-attention gate (SAG) is also utilized to capture the spatial relationships in different channels and further re-weight the channels in feature maps by following the design of non-local operation and channel attention. Furthermore, the upsampling mechanism in original Feature Pyramid Network (FPN) is improved by adopting the transpose convolution and skip concatenation to fine-tune the feature maps. The Ultrasound Brachial Plexus Dataset (UBPD) is also proposed to support the research on brachial plexus segmentation, which consists of 1055 ultrasound images with four objects (i.e., nerve, artery, vein and muscle) and their corresponding label masks. Extensive experimental results using UBPD dataset demonstrate that MallesNet can achieve a better segmentation performance on nerves structure and also on surrounding structures in comparison to other competing approaches.


Brachial Plexus , Image Processing, Computer-Assisted , Brachial Plexus/diagnostic imaging , Humans , Image Processing, Computer-Assisted/methods , Ultrasonography
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