1.
Chem Commun (Camb)
; 58(65): 9116-9119, 2022 Aug 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-35880535
RESUMEN
The intrinsic photochemistry of the isoxazole, a common heterocycle in medicinal chemistry, can be applied to offer an alternative to existing strategies using more perturbing, extrinsic photo-crosslinkers. The utility of isoxazole photo-crosslinking is demonstrated in a wide range of biologically relevant experiments, including common proteomics workflows.