Asunto(s)
Ligamento Cruzado Anterior/cirugía , Plastía con Hueso-Tendón Rotuliano-Hueso/efectos adversos , Chryseobacterium/aislamiento & purificación , Infecciones por Flavobacteriaceae/microbiología , Traumatismos de la Rodilla/cirugía , Infección de la Herida Quirúrgica/microbiología , Tendón Calcáneo/microbiología , Tendón Calcáneo/trasplante , Adulto , Lesiones del Ligamento Cruzado Anterior , Antibacterianos/uso terapéutico , Artroscopía , Desbridamiento , Humanos , Masculino , Persona de Mediana Edad , Reoperación , Infección de la Herida Quirúrgica/terapia , Irrigación Terapéutica , Trasplante Homólogo/efectos adversosRESUMEN
We describe a case of Creutzfeldt-Jakob disease associated with a dura mater graft (Lyodura brand) in a 26-year-old man who underwent several neurosurgical procedures as a child. Clinicians and infection control personnel should be aware that recipients of Lyodura brand dura mater grafts processed before May 1987 may remain at increased risk for Creutzfeldt-Jakob disease throughout their lives.
Asunto(s)
Colágeno/efectos adversos , Síndrome de Creutzfeldt-Jakob/transmisión , Duramadre/trasplante , Trasplante de Tejidos/efectos adversos , Niño , Infección Hospitalaria/etiología , Infección Hospitalaria/transmisión , Duramadre/cirugía , Humanos , Hidrocefalia/cirugía , Masculino , Meningomielocele/cirugíaRESUMEN
Attention Deficit Hyperactivity Disorder (ADHD) is seen in the majority of children with Fragile X Syndrome (FraX). Previous work has documented an enhanced sweat response to stimuli in children with FraX compared to controls utilizing electrodermal response (EDR) measures. The present study assesses the EDRs both on and off stimulants in 19 children with ADHD and FraX compared to 17 age- and IQ-matched control patients with ADHD and developmental delays. Although the baseline EDRs were comparable between FraX patients and controls, the patients with FraX had a significant decrease in EDR amplitude and number of peaks when treated with stimulants compared to controls. This suggests that patients with FraX are more responsive to the enhancement of inhibitory systems that occur with stimulant use for ADHD. The use of a quantifiable measure, such as EDR, is recommended in future studies of treatment efficacy.