Radiographic measurement for femoral varus in Pomeranian dogs with and without medial patellar luxation.

OBJECTIVES: To measure radiographically the inclination angle (ICA), femoral varus angle (FVA), anatomical lateral distal femoral angle (aLDFA), and mechanical lateral distal femoral angle (mLDFA) in Pomeranian dogs with and without medial patellar luxation (MPL). MATERIALS AND METHODS: Stifles of 34 Pomeranian dogs were graded and allocated into three groups: normal, grades I-II MPL, and grade III MPL. Angle values were measured from craniocaudal radiographs of the hindlimbs by each of the three examiners on three separate occasions. RESULTS: Each of the three groups consisted of 15 stifles. Means ± SD for the ICA, FVA, aLDFA and mLDFA in the normal stifles were 136.46 ± 7.12°, 5.85 ± 3.18°, 95.21 ± 3.48° and 99.46 ± 4°, respectively. No significant differences (p>0.05) in the measured values for the ICA between groups were observed. The FVA, aLDFA and mLDFA values in grade III MPL group were significantly (p<0.05) greater than those in the other two groups. Significant differences in the three angles between the normal and grades I-II MPL groups were not observed. CLINICAL SIGNIFICANCE: Significant change of distal femoral varus exists in Pomeranian dogs with grade III MPL.

Evaluating the effects of 14-day oral vedaprofen and tolfenamic acid treatment on renal function, hematological and biochemical profiles in healthy cats.

The objective of this study was to evaluate the effects of the nonsteroidal anti-inflammatory drugs vedaprofen and tolfenamic acid on renal function after oral administration for 2 weeks in healthy cats. Experiments were performed using nineteen domestic short-haired cats randomly divided into one control (n=6) and two treatment groups. All cats in the first (n=6) and second treatment groups (n=7) received vedaprofen (0.5 mg/kg/day) and tolfenamic acid (4 mg/kg/day), respectively. During the experiment, renal function was evaluated using percent renal uptakes of (99m)Technetium-diethylenetriamine-pentaacetic acid ((99m)Tc-DTPA) collected from renal scintigraphy and blood samples used to determine complete blood count and biochemical profiles. Renal scintigraphy and blood collections were performed at days 0, 5, 11, 15, and 45. The percent of renal uptake after the administration of vedaprofen and tolfenamic acid were not significantly different compared to pretreatment (day 0) and control group levels. In addition, significant changes were not observed in hematological and biochemical profiles within or between groups, with the exception of slightly lower numbers in red blood cell counts compared to the normal value on day 45 in the tolfenamic acid-treated group. Taken together, we conclude 14-day administration of vedaprofen and tolfenamic acid might not cause any adverse effects on renal function, hematological and serum biochemical variables.

Ischial ostectomy in direct end-to-end anastomosis of the pelvic urethra in male dogs.

Ischial ostectomy in conjunction with direct end-to-end anastomosis of the pelvic urethra was performed after prostatectomy in cadavers of 10 male dogs with normal bladder and urethra, and in a mongrel dog with an enlarged prostrate and transection injury of the pelvic urethra. In the cadavers, tension on the suture line was assessed from the intravesical pressure (IVP) and volume of normal saline solution (NSS) instilled into the bladder to cause dehiscence of the anastomosis before and after the ostectomy. The experiment found that the IVP and instilled NSS volume after the ischial ostectomy were significantly (p<0.01) higher than those before the ostectomy, suggesting the ostectomy can reduce tension on the suture line and risk of dehiscence. Clinically, the dog had uneventful recovery with normal urination. Fluoroscopic examination of the caudal abdomen at 3 and 16weeks after surgery revealed urethral continuity without perforation and narrowing of the anastomosis site.