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1.
Schizophr Res ; 250: 172-179, 2022 Dec.
Article En | MEDLINE | ID: mdl-36423442

There is growing clinical interest in addressing relationship dynamics between service-users and their voices. The Talking With Voices (TwV) trial aimed to establish feasibility and acceptability of a novel dialogical intervention to reduce distress associated with voices amongst adults diagnosed with schizophrenia spectrum disorders. The single-site, single-blind (rater) randomised controlled trial recruited 50 participants who were allocated 1:1 to treatment as usual (TAU), or TAU plus up to 26 sessions of TwV therapy. Participants were assessed at baseline and again at end of treatment (six-months). The primary outcomes were quantitative and qualitative assessments of feasibility and acceptability. Secondary outcomes involved clinical measures, including targeted instruments for voice-hearing, dissociation, and emotional distress. The trial achieved 100 % of the target sample, 24 of whom were allocated to therapy and 26 to TAU. The trial had high retention (40/50 [80 %] participants at six-months) and high intervention adherence (21/24 [87.5 %] receiving ≥8 sessions). Signals of efficacy were shown in targeted measures of voice-hearing, dissociation, and perceptions of recovery. Analysis on the Positive and Negative Syndrome Scale indicated that there were no differences in means of general psychosis symptom scores in TwV compared to the control group. There were four serious adverse events in the therapy group and eight in TAU, none of which were related to study proceedings. The trial demonstrates the acceptability of the intervention and the feasibility of delivering it under controlled, randomised conditions. An adequately powered definitive trial is necessary to provide robust evidence regarding efficacy evaluation and cost-effectiveness. Trial registration: ISRCTN 45308981.


Psychosocial Intervention , Psychotic Disorders , Adult , Humans , Feasibility Studies , Single-Blind Method , Hallucinations/etiology , Hallucinations/therapy , Hallucinations/psychology , Psychotic Disorders/complications , Psychotic Disorders/therapy
2.
Psychol Psychother ; 94(3): 558-572, 2021 09.
Article En | MEDLINE | ID: mdl-33629816

PURPOSE: To present a treatment protocol for delivering Talking With Voices, a novel intervention for people with psychosis that involves dialogical engagement with auditory hallucinations. METHOD: This paper presents a manualized approach to therapy employed in the Talking With Voices trial, a feasibility and acceptability randomized control trial of 50 adult participants. A rationale for following a treatment manual is provided, followed by the theoretical underpinnings of the intervention and its principles and values, including the main tenet that voices can often be understood as dissociated parts of the self which serve a protective function by indicating social-emotional vulnerabilities. The four therapy phases for improving the relationship between the voice-hearer and their voices are outlined: (1) engagement and psychoeducation, (2) creating a formulation, (3) dialoguing with voices, and (4) consolidating outcomes, including key milestones at each phase. Implementation issues are discussed, as well as recommendations for best practice and future research. RESULTS: The Talking With Voices treatment protocol indicates that it is feasible to manualize a dissociation-based approach to support service users who are distressed by hearing voices. CONCLUSION: For some individuals, it is possible to engage in productive dialogue with even extremely hostile or distressing voices. Developing coping strategies, creating a formulation, and ultimately establishing a dialogue with voices has the potential to improve the relationship between voice(s) and voice-hearer. Further research is now required to evaluate feasibility, acceptability, and efficacy. PRACTITIONER POINTS: It is feasible to integrate a dissociation model of voice-hearing within a psychological intervention for people with psychosis. Combining psychosocial education, formulation and direct dialogue can be used to facilitate a more peaceful relationship between clients and their voices. Practitioners trained in other therapeutic modalities can draw on existing transferrable skills to dialogue with their clients' voices. The input of those with lived experience of mental health difficulties has an important role in guiding treatment design and delivery.


Psychotic Disorders , Voice , Adult , Clinical Protocols , Hallucinations/therapy , Humans , Pilot Projects , Psychotic Disorders/therapy , Randomized Controlled Trials as Topic
3.
BMJ Open ; 10(6): e035709, 2020 06 04.
Article En | MEDLINE | ID: mdl-32503871

OBJECTIVES: Mental healthcare is commonly aimed at reducing symptoms in individual service users. When only symptomatic recovery is addressed, not all service users experience sufficient recovery, and when care is aimed only at individuals (instead of the neighbourhood), not all people in need of mental healthcare are reached. This study evaluated a project that aimed to improve mental healthcare in a neighbourhood, by improving healthcare providers' outreach to the residents living in the neighbourhood, by improving collaboration among healthcare providers and focussing on the residents' personal recovery. This project was carried out by several public health services. It aimed to change the goal of mental healthcare provided in the neighbourhood from symptom reduction to personal recovery. DESIGN: The study included qualitative focus groups and inductive content analysis. SETTING: Primary and secondary mental healthcare that healthcare workers from different healthcare services provided. PARTICIPANTS: The evaluation was conducted through three focus group interviews with services users, their friends and relatives, neighbourhood residents, neighbourhood representatives and the healthcare services that were involved (n = 24). RESULTS: Evaluation indicated that the most valued part of the project was the utilisation of peer workers at the initiation of mental healthcare. Improved communication among healthcare providers that the project fostered was also highly regarded. The aim of the project to align it with existing initiatives in the neighbourhood was also considered important, although it was difficult to achieve. CONCLUSIONS: The project did not find a panacea for recovery-oriented community mental healthcare. A variety of its components did, however, contribute to the mental health of the community residents.


Community Mental Health Services/methods , Community Mental Health Services/standards , Female , Focus Groups , Humans , Male , Mental Disorders/therapy , Middle Aged , Program Evaluation , Quality Assurance, Health Care/methods , Quality Assurance, Health Care/organization & administration , Quality Assurance, Health Care/standards , Quality Improvement/organization & administration , Quality Improvement/standards , Remission Induction
4.
J Forensic Leg Med ; 54: 74-75, 2018 Feb.
Article En | MEDLINE | ID: mdl-29328965

We describe a case of a 51-year old man who used GHB only in the afternoon and evening during 10 consecutive days in a recreational way: 20 ml a day in 4 ml per 2-3 hrs. He developed an excited delirium syndrome at the second day after stopping. Apparently even after relatively short recreational use severe disruptive behavior can develop. This is a unique case in literature. References are provided.


Delirium/chemically induced , Sodium Oxybate/adverse effects , Substance Withdrawal Syndrome/complications , Humans , Male , Middle Aged
5.
Schizophr Bull ; 40 Suppl 4: S285-94, 2014 Jul.
Article En | MEDLINE | ID: mdl-24936088

The international Hearing Voices Movement (HVM) is a prominent mental health service-user/survivor movement that promotes the needs and perspectives of experts by experience in the phenomenon of hearing voices (auditory verbal hallucinations). The main tenet of the HVM is the notion that hearing voices is a meaningful human experience, and in this article, we discuss the historical growth and influence of the HVM before considering the implications of its values for research and practice in relation to voice-hearing. Among other recommendations, we suggest that the involvement of voice-hearers in research and a greater use of narrative and qualitative approaches are essential. Challenges for implementing user-led research are identified, and avenues for future developments are discussed.


Adaptation, Psychological , Hallucinations , Patient Advocacy , Schizophrenia , Schizophrenic Psychology , Humans , Patient Participation , Peer Group , Research , Self-Help Groups
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