Biologics have significantly advanced the treatment of inflammatory disorders, including psoriasis. However, their use in immunosuppressed patients, such as those with solid-organ transplants, is less understood. These patients often face dermatological issues, but inflammatory skin diseases are rare due to their immunosuppressive treatments. Our study aims to assess biologics' effectiveness in such immunocompromised patients. We report a case from our institution of a 29-year-old man with a history of psoriasis, who underwent a kidney transplant and later developed erythroderma. He did not respond to traditional treatments and was successfully treated with adalimumab, leading to the discontinuation of MMF. We also reviewed literature in solid organ transplant patients with psoriasis. Our findings, based on 10 articles, indicate a cautious approach to using biologics in this group, with further research needed for efficacy and safety.
Adalimumab , Biological Products , Kidney Transplantation , Psoriasis , Humans , Psoriasis/drug therapy , Male , Adult , Biological Products/therapeutic use , Biological Products/adverse effects , Adalimumab/therapeutic use , Adalimumab/adverse effects , Immunocompromised Host , Immunosuppressive Agents/therapeutic use , Immunosuppressive Agents/adverse effects , Transplant Recipients
BACKGROUND: Research has shown that patients may turn to social media seeking information regarding diagnosis and treatment. This study aimed to analyze and compare content related to hidradenitis suppurativa (HS) using the "hashtag" tool across three of the most popular social media platforms to determine the information that patients are exposed to online. METHODS: We identified hashtags across Instagram, TikTok, and Facebook for "#hidradenitissuppurativa." The top 50 videos returned by the algorithm across each site were selected for analysis. Data extracted for comparison included content creator demographics, number of followers, type of content (educational vs. noneducational), and associated hashtags. RESULTS: Sixty-seven percent of posts were created by females (n = 101/150), 10% by males (n = 16/150), and 22% other (n = 33/150). Distribution was similar across all platforms. User accounts on TikTok have a significantly higher number of followers (median = 38,700, range = 902-17,600,000 followers) compared to Facebook (median = 1,375, range = 58-777,000 followers) and Instagram (median = 2,818, range = 57-9,800 followers). CONCLUSION: This study suggests that there is a disproportionate number of patients creating content to raise awareness on HS on social media compared to patient support groups or medical professionals. We propose that social media is a useful platform that dermatologists and official institutional bodies can utilize as an alternative method of health promotion and patient education. Further research to explore social media trends across a range of dermatological conditions can help guide targeted education campaigns in the future.
Hidradenitis Suppurativa , Social Media , Female , Humans , Male , Algorithms , Cross-Sectional Studies , Information Seeking Behavior , Consumer Health Information , Health Promotion , Awareness
A 74-year-old man was referred with a 10-year history of a plaque on the left buttock. Prior to presentation to dermatology, he had undergone biopsy under plastic surgery for a presumptive diagnosis of psoriasis, but histology was nonspecific. Further clinical examination and repeat biopsies were needed for the diagnosis.
Buttocks , Aged , Biopsy , Buttocks/pathology , Humans , Male
