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1.
Health Expect ; 27(3): e14098, 2024 Jun.
Article En | MEDLINE | ID: mdl-38859797

OBJECTIVE: Obesity is a complex, chronic, relapsing disease that requires an individualised approach to treatment. However, weight stigma (WS) experienced in healthcare settings poses a significant barrier to achieving person-centred care for obesity. Understanding the experiences of people living with obesity (PwO) can inform interventions to reduce WS and optimise patient outcomes. This study explores how patients with obesity perceive WS in general practice settings; its impact on their psychological well-being and health behaviours, and the patients suggestions for mitigating it. METHODS: In-depth semistructured interviews were conducted with 11 PwO who had experienced WS in general practice settings in Ireland. The interviews were conducted online via Zoom between May and August 2023; interviews lasted between 31 and 63 min (M = 34.36 min). Interviews were audio-recorded, transcribed verbatim and analysed using inductive reflexive thematic analysis. RESULTS: Three overarching themes specific to participants' experience of WS in general practice were generated: (1) shame, blame and 'failure'; (2) eat less, move more-the go-to treatment; (3) worthiness tied to compliance. A fourth theme: (4) the desire for a considered approach, outlines the participants' suggestions for reducing WS by improving the quality of patient-provider interactions in general practice. CONCLUSION: The findings call for a paradigm shift in the management of obesity in general practice: emphasising training for GPs in weight-sensitive communication and promoting respectful, collaborative, and individualised care to reduce WS and improve outcomes for people with obesity. PATIENT OR PUBLIC CONTRIBUTION: PPI collaborators played an active and equal role in shaping the research, contributing to the development of the research questions, refining the interview schedule, identifying key themes in the data, and granting final approval to the submitted and published version of the study.


General Practice , Interviews as Topic , Obesity , Qualitative Research , Social Stigma , Humans , Obesity/psychology , Obesity/therapy , Female , Male , Middle Aged , Ireland , Adult , Aged , Health Behavior
2.
BMJ Open ; 14(4): e081066, 2024 Apr 15.
Article En | MEDLINE | ID: mdl-38626981

OBJECTIVES: The objective of this study was to explore how people living with obesity who use obesity services perceive healthcare professionals' (HCPs) online representation of the disease on social media. By exploring their perspective, we aimed to develop a framework to inform good practice around social media use for HCPs. DESIGN: This was a qualitative study using a phenomenological framework. Following in-depth semi-structured interviews, analysis was undertaken to identify superordinate themes relating to how HCPs portray living with obesity online. SETTING: Patient advocacy organisation (The Irish Coalition for People Living with Obesity) and three clinical sites offering obesity treatment in Ireland. PARTICIPANTS: 15 adult participants comprising of 12 women and 3 men who use social media and are living with obesity and who use obesity services. RESULTS: Three key themes of how people living with obesity who use obesity services perceive HCP's online representation of the disease. (1) Negative experiences of HCPs-participants describe encountering weight stigma and bias on social media from HCPs that they characterised as simplistic and outdated conceptualisations. These engender shame, fear and anger. (2) Positive experience of HCPs-participants report social media allows HCPs to educate and inform public perception of obesity. Positive online experiences lead to feelings of inclusion, understanding and encouragement. (3) Expectations of HCPs-qualifications, professional titles and academic association affected the perceived trustworthiness of information and its impact on readers. Participants feel there is a duty of care for HCPs in obesity medicine to advocate and be active online to provide accurate medical information. CONCLUSION: HCP's use of social media has a powerful impact on people with obesity who use healthcare and obesity services. Social media is a key tool in obesity awareness and education. We propose the '3E' framework-Empower, Evidence-Based and Educate and be educated to guide HCPs' social media use.


Social Media , Adult , Male , Humans , Female , Obesity/therapy , Delivery of Health Care , Fear , Qualitative Research , Health Personnel
3.
Endocrine ; 83(2): 392-398, 2024 Feb.
Article En | MEDLINE | ID: mdl-37735340

BACKGROUND: Obesity is defined as excess adipose tissue causing a deterioration in health, but diagnosing the causes and deciding on treatment can be challenging. Several randomized controlled clinical trials (RCT) have demonstrated the effectiveness of semaglutide as a treatment for obesity. This study investigated the clinical response to semaglutide as a weight loss treatment in a real-world setting. METHODS: This observational study investigated the response to injectable semaglutide in the first 3 months during the dose titration phase up to 1 mg. Weight loss after 6 months was also evaluated. The data were collected from the electronic medical records (EMR) from outpatient clinics between July 2021 to March 2023. All participants were older than 18 years, with no history of bariatric surgery within 1 year, and had a least one prescription of injectable semaglutide. The primary outcome was weight change at 3 months. Weight loss in those patients who attended at 6 months was a secondary outcome. RESULTS: A total of 350 patients were included in the study. The vast majority (80.3%) were female. 287 patients (82%) completed 3 months on injectable semaglutide and lost 6.6 ± 3.8% bodyweight. 224 patients (64%) completed 6 months on semaglutide and lost 12 ± 6.1% bodyweight. 188 (65.5%) of patients who completed 3-month follow-up lost ≥5% weight, 39 (13.5%) patients lost ≥10% weight, and 7 (2.4%) patients lost ≥15% weight. While for those patients who completed the 2nd visit (n = 224), 201 (89.7%) lost ≥5% weight, 135 (60.3%) lost ≥10% weight, and 54 (24.1%) lost ≥ 15% body weight. CONCLUSION: Injectable semaglutide in a real-world setting resulted in similar weight loss and had a similar side effect profile as was observed in randomized controlled trials.


Diabetes Mellitus, Type 2 , Glucagon-Like Peptides , Adult , Female , Humans , Male , Diabetes Mellitus, Type 2/drug therapy , Glucagon-Like Peptides/therapeutic use , Obesity/drug therapy , Treatment Outcome , Weight Loss
4.
Obes Rev ; 24(10): e13606, 2023 10.
Article En | MEDLINE | ID: mdl-37533183

Weight stigma research is largely focused on quantifiable outcomes with inadequate representation of the perspectives of those that are affected by it. This study offers a comprehensive systematic review and synthesis of weight stigma experienced in healthcare settings, from the perspective of patients living with obesity. A total of 1340 studies was screened, of which 32 were included in the final synthesis. Thematic synthesis generated three overarching analytical themes: (1) verbal and non-verbal communication of stigma, (2) weight stigma impacts the provision of care, and (3) weight stigma and systemic barriers to healthcare. The first theme relates to the communication of weight stigma perceived by patients within patient-provider interactions. The second theme describes the patients' perceptions of how weight stigma impacts upon care provision. The third theme highlighted the perceived systemic barriers faced by patients when negotiating the healthcare system. Patient suggestions to reduce weight stigma in healthcare settings are also presented. Weight stigma experienced within interpersonal interactions migrates to the provision of care, mediates gaining equitable access to services, and perpetuates a poor systemic infrastructure to support the needs of patients with obesity. A non-collaborative approach to practice and treatment renders patients feeling they have no control over their own healthcare requirements.


Weight Prejudice , Humans , Obesity , Social Stigma , Attitude of Health Personnel , Qualitative Research
5.
Obes Facts ; 15(6): 736-752, 2022.
Article En | MEDLINE | ID: mdl-36279848

BACKGROUND: This Clinical Practice Guideline (CPG) for the management of obesity in adults in Ireland, adapted from the Canadian CPG, defines obesity as a complex chronic disease characterised by excess or dysfunctional adiposity that impairs health. The guideline reflects substantial advances in the understanding of the determinants, pathophysiology, assessment, and treatment of obesity. SUMMARY: It shifts the focus of obesity management toward improving patient-centred health outcomes, functional outcomes, and social and economic participation, rather than weight loss alone. It gives recommendations for care that are underpinned by evidence-based principles of chronic disease management; validate patients' lived experiences; move beyond simplistic approaches of "eat less, move more" and address the root drivers of obesity. KEY MESSAGES: People living with obesity face substantial bias and stigma, which contribute to increased morbidity and mortality independent of body weight. Education is needed for all healthcare professionals in Ireland to address the gap in skills, increase knowledge of evidence-based practice, and eliminate bias and stigma in healthcare settings. We call for people living with obesity in Ireland to have access to evidence-informed care, including medical, medical nutrition therapy, physical activity and physical rehabilitation interventions, psychological interventions, pharmacotherapy, and bariatric surgery. This can be best achieved by resourcing and fully implementing the Model of Care for the Management of Adult Overweight and Obesity. To address health inequalities, we also call for the inclusion of obesity in the Structured Chronic Disease Management Programme and for pharmacotherapy reimbursement, to ensure equal access to treatment based on health-need rather than ability to pay.


Obesity , Overweight , Adult , Humans , Ireland , Canada , Obesity/therapy , Obesity/psychology , Overweight/therapy , Weight Loss , Chronic Disease
6.
J Clin Sleep Med ; 18(3): 885-894, 2022 Mar 01.
Article En | MEDLINE | ID: mdl-34725036

STUDY OBJECTIVES: To assess the effectiveness of continuous positive airway pressure (CPAP) management guided by CPAP machine downloads in newly diagnosed patients with obstructive sleep apnea (OSA) using electronic health record-derived health care utilization, biometric variables, and laboratory data. METHODS: Electronic health record data of patients seen at the University of Utah Sleep Program from 2012-2015 were reviewed to identify patients with new diagnosis of OSA in whom CPAP adherence and residual apnea-hypopnea index as measured by a positive airway pressure adherence tracking device data for ≥ 1 year were available. Biometric data, laboratory data, and system-wide charges were compared in the 1 year before and after CPAP therapy. Subgroups were divided by whether patients met tracking criteria, mean nightly usage, and OSA severity. RESULTS: 976 consecutive, newly diagnosed participants with OSA (median age 55 years, 56.6% male) met inclusion criteria. There was a mean decrease of systolic blood pressure (BP) of 1.2 mm Hg and diastolic BP of 1.0 mm Hg within a year of initiation of CPAP therapy. BP improvements in the subgroup meeting CPAP tracking targets were 1.36 mmHg (systolic) and 1.37 mmHg (diastolic). No significant change was noted in body mass index, glycated hemoglobin, or serum creatinine values within a year of starting CPAP therapy, and health care utilization increased (mean acute care visits 0.22 per year to 0.53 per year; mean charges of $3,997 per year to $8,986 per year). CONCLUSIONS: An improvement in BP was noted within a year of CPAP therapy in newly diagnosed patients with OSA, with no difference in the magnitude of improvement between those meeting tracking system adherence targets. CITATION: Locke BW, Neill SE, Howe HE, Crotty MC, Kim J, Sundar KM. Electronic health record-derived outcomes in obstructive sleep apnea managed with positive airway pressure tracking systems. J Clin Sleep Med. 2022;18(3):885-894.


Electronic Health Records , Sleep Apnea, Obstructive , Blood Pressure , Continuous Positive Airway Pressure , Female , Humans , Male , Middle Aged , Patient Compliance , Sleep , Sleep Apnea, Obstructive/therapy
8.
Spine J ; 7(6): 689-93, 2007.
Article En | MEDLINE | ID: mdl-17998128

BACKGROUND CONTEXT: The halo skeletal fixator provides the most rigid type of immobilization of all the orthoses that stabilize the cervical spine. Sometimes with older patients (>70 years old), the pin penetrates the cortical and cancellous bone of the skull and enters the intracranial space, which can result in serious complications such as brain injury, infection, hematoma, and loss of cerebrospinal fluid from the subarachnoid space. Currently, there is a lack of relevant literature that examines these concerns. PURPOSE: To evaluate the thickness of the outer table, diploe, and inner table at the anterolateral and posterolateral pin insertion areas of the skull in elderly cadavers by using computed tomography (CT) scans. In addition, insertion torques at the four standard pin insertion areas was determined by applying halo pins at incremental torque in an effort to suggest safe torque levels for the anterolateral and posterolateral pins. STUDY DESIGN/SETTING: A human cadaveric anatomical and biomechanical study relating to thickness and insertion torques at standard pin areas in the elderly. PATIENT SAMPLE: Twenty-one elderly cadaveric skull specimens. OUTCOME MEASURES: Thickness of cortices (tables) and diploe of skull and insertion torque at halo pin insertion areas. METHODS: Aquarius Image software at the CT scanner's TeraRecon Aquarius Workstation was used to make the necessary skull thickness measurements at the pin insertion areas. Six, 8, 12, 18, and 36 inch lb of torque were used to determine penetration of the pins through the inner table at each of the four locations (two anterolateral and two posterolateral). RESULTS: The mean anterolateral thickness was 7.36+/-1.57 mm. The average thickness of the outer table, diploe, and inner table were 2.24+/-0.44 mm, 1.52+/-0.41 mm, and 3.59+/-1.70 mm, respectively. The mean posterolateral thickness was 9.47+/-1.12 mm. The average thickness of the outer table, diploe, and inner table were 4.32+/-0.92 mm, 1.88+/-0.35 mm, and 3.27+/-1.21 mm, respectively. No pin penetration was seen at the traditional 8 inch lb of insertion torque in both the anterolateral and posterolateral pin insertion areas. Eighteen inch lb of torque resulted in penetration in 90.48% (19/21) and in 85.71% (18/21) of specimens in the left anterolateral and right anterolateral pin insertion areas, respectively. No penetration was seen even at 36 inch lb of torque in 80.95% (17/21) of the cadavers in both the left and right posterolateral pin insertion areas. CONCLUSIONS: The current study supported previous research that 8 inch lb of torque is safe for application of halo pins in the elderly. The posterolateral skull is thicker and stronger than the anterolateral skull. The safe maximum torque is 8 inch lb for anterolateral pin insertion area and 18 inch lb for the posterolateral pin insertion area.


Bone Nails/adverse effects , Prosthesis Failure , Skull/diagnostic imaging , Skull/surgery , Tomography, X-Ray Computed , Aged , Aged, 80 and over , Cadaver , Craniotomy , External Fixators/adverse effects , Female , Humans , Male , Postoperative Complications/prevention & control , Skull/anatomy & histology , Torque
9.
Int Zoo Yearb ; 24(1): 77-99, 1986 Jan.
Article En | MEDLINE | ID: mdl-32336816

In assessing the situation revealed by the survey, we concluded that in general when sufficient numbers of founders were available and attention paid to the animals general and specific needs, including preventative medicine, the captive populations have done reasonably well. Is is obvious that some small groups, such as the small African antelope and the duikers, need highly specialised care and there is a great deal of work still to be done on their husbandry. The mountain or alpine species have been fairly successful with the goats showing the greatest adaptability. We feel there are grounds for optimism for the future of such animals as the Rocky mountain goat, the Japanese serow and even the Blue sheep. Of those species whose captive future is still in doubt, particularly those which are threatened in the wild, our researches indicate that concentrated efforts should be made to obtain sufficient founder stock to establish self-sustaining populations as a hedge against total disaster in the wild. We felt that the evidence was strong that any of the ungulate species reviewed could be successfully maintained in captivity given the right circumstances. Basically, the husbandry procedures of all the reporting zoos were similar, although, of course, each zoo had its own variations. In some cases these measurably affected the success of the animal population. In the last 20 to 25 years inter-zoo co-operation and sharing of information has greatly expanded. Nevertheless we would now urge that even more emphasis should be put on the exchange of information to provide each zoo with up- to-date data which would ensure that all zoos are kept abreast with the 'state of the art. With such a spirit of co-operation the prospect of managing species as total captive populations appears to be practical and promising.

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