RESUMEN
Ancient DNA shows continuity between living and ancient Maya communities.
Asunto(s)
Conducta Ceremonial , Civilización , ADN Antiguo , Gemelos , Femenino , Humanos , Masculino , Historia Antigua , Gemelos/historia , Niño , Civilización/historiaRESUMEN
Complex tools from 300,000-year-old deposit at Schöningen in Germany point to a "wood age".
Asunto(s)
Hombre de Neandertal , Madera , Animales , Arqueología , Alemania , Hombre de Neandertal/psicologíaRESUMEN
Moderns made mysterious ice age artifacts-implying overlap with Neanderthals.
Asunto(s)
Hombre de Neandertal , Animales , Humanos , Europa (Continente) , FósilesRESUMEN
Among Europeans, risk of multiple sclerosis rises with genes from Bronze Age Yamnaya herders.
Asunto(s)
ADN Antiguo , Esclerosis Múltiple , Humanos , Europa (Continente)/epidemiología , Genoma Humano , Esclerosis Múltiple/epidemiología , Esclerosis Múltiple/genética , Esclerosis Múltiple/historiaRESUMEN
8000 years ago-long before farming arrived-people in Siberia built defensive structures.
Asunto(s)
Caza , Humanos , Granjas/historia , Siberia , Caza/historiaRESUMEN
Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum neurotoxins. This review summarizes the literature on the safety of HSA. Beyond decades of safe use, the largest clinical dataset of HSA safety is a large meta-analysis of HSA supplier data, which found only an extremely remote risk of serious adverse events across millions of doses of therapeutic concentrations of HSA. There is a paucity of literature identifying HSA-specific adverse events when used as a stabilizer/excipient; however, studies of HSA-containing botulinum neurotoxins (BoNTs) suggest that adverse events are not related to HSA. Polysorbates, which are synthetically produced and not physiologically inert, are contained in pending or new-to-market BoNT formulations. In contrast to HSA, evidence exists to suggest that polysorbates (particularly PS20/PS80) can cause serious adverse events (e.g., hypersensitivity, anaphylaxis, and immunogenicity).
Asunto(s)
Toxinas Botulínicas Tipo A , Toxinas Botulínicas , Humanos , Toxinas Botulínicas/efectos adversos , Albúmina Sérica Humana/efectos adversos , Excipientes , Polisorbatos , Toxinas Botulínicas Tipo A/efectos adversosRESUMEN
Giant family trees based on ancient DNA from thousands of people are revealing prehistoric politics and social structure.
RESUMEN
DNA from enslaved Black workers at a 19th century iron forge links them to living descendants. But the research swirls with ethical questions.
RESUMEN
Genes reveal striking diversity within similar ice age cultures.
Asunto(s)
Diversidad Cultural , ADN Antiguo , Europa (Continente) , HumanosRESUMEN
After the Spanish conquest, horses transformed Native American tribes much earlier than historians thought.
Asunto(s)
Indio Americano o Nativo de Alaska , Caballos , Interacción Humano-Animal , Animales , América del Norte , España , Arqueología , HumanosRESUMEN
Ancient DNA reflects foreign influx to Swahili coast, but its culture is largely local.
RESUMEN
Analysis reveals the chemicals applied to corpses in a 2700-year-old mummification workshop.
Asunto(s)
Momias , Humanos , Cadáver , Egipto , Historia Antigua , Momias/historiaRESUMEN
Meat from the butchered beasts would have fed hundreds.
Asunto(s)
Conducta Alimentaria , Procesos de Grupo , Caza , Carne , Hombre de Neandertal , Animales , Ingestión de Alimentos , Carne/historia , Hombre de Neandertal/psicología , Caza/historia , ElefantesRESUMEN
DNA from a medieval German cemetery opens a window on the history of today's largest Jewish population.
Asunto(s)
Judíos , Judíos/genética , Población/genética , Alemania , Cementerios/historia , ADN Antiguo , HumanosRESUMEN
By sequencing ancient hominins' DNA, Pääbo explored "what makes us uniquely human".
Asunto(s)
ADN Antiguo , Hominidae , Animales , Hominidae/genética , Humanos , Premio NobelRESUMEN
Genetic study of burials suggests whole families migrated to the island in the first millennium C.E.
Asunto(s)
Emigración e Inmigración , Población Blanca , Entierro , ADN Antiguo , Emigración e Inmigración/historia , Inglaterra , Historia Antigua , Humanos , Análisis de Secuencia de ADN , Población Blanca/genéticaRESUMEN
Studies seek clues to origins of farming, early languages.
Asunto(s)
Civilización , ADN Antiguo , Granjas , Lenguaje , Civilización/historia , Granjas/historia , Historia Antigua , Humanos , Lenguaje/historia , Medio OrienteRESUMEN
Russian disinformation campaign targets routine research on bat parasites.
RESUMEN
Researchers hide ancient weapons and bat skulls, upload data as bombs fall.