[Retinal capillary blood flow in exudative age-related macular degeneration]. / Przeplyw krwi w mikrokrazeniu siatkówkowym u chorych na postac wysiekowa zwyrodnienia plamki zwiazanego z wiekiem.

PURPOSE: The purpose of this study was to evaluate retinal capillary blood flow in patients with exudative AMD. MATERIAL AND METHODS: Twenty patients with exudative AMD and twenty four patients age-matched control subjects, were included into the study. Retinal capillary blood flow was evaluated with Heidelberg Retinal Flowmeter (HRF), measurements were taken in two macular regions. The total mean flow and mean velocity were calculated usingthe technique of automatic full field perfusion image analysis (AFFPIA). The U Mann-Whitney test was used for statistical analysis. RESULTS: Patients with exudative AMD revealed slightly lower retinal blood flow than control subjects in area I and in area II. In the AMD group total mean flow values were: 295.75 AU/ 303.85 AU, while in the control group were: 302.37 AU/ 304.42 AU. The mean velocity values were: 1.48 AU/ 1.42 AU in AMD patients and: 1.49 AU/ 1.52 AU in control group. The differences did not reach the statistical significance. CONCLUSIONS: The study results showed no changes in retinal capillary blood flow in patients with exudative AMD comparing to normal subjects.

[Retinal capillary blood flow in nonexudative age-related macular degeneration]. / Przeplyw krwi w mikrokrazeniu siatkówkowym u os6b z postaciq suchq zwyrodnienia plamki zwiqzanego z wiekiem.

PURPOSE: The purpose of this study was to evaluate retinal capillary blood flow in patients with nonexudative age-related macular degeneration. MATERIAL AND METHODS: Twenty five patients with nonexudative age-related macular degeneration and twenty five age-matched control subjects were enrolled into the study. Full ophthalmological examination and fluorescein angiography were performed. Retinal blood flow was evaluated with the Heidelberg Retina Flowmeter. Total mean flow and mean velocity were calculated using the technique of automatic full field perfusion image analysis RESULTS: Patients with nonexudative age-related macular degeneration revealed statistically significant lower retinal blood flow than control subjects. In AMD group total mean flow values were 266.89 / 272.21 AU, while in control group were: 1.498 / 1.509 AU. Mean velocity values were: 1.315 / 1.329 AU in AMD patients and: 1.498 / 1.509 AU in controls. CONCLUSIONS: The study results showed reduced capillary retinal blood flow in patients with age-related macular degeneration compared to normal subjects. This retinal microcirculation impairment suggests more generalized perfusion defect involving both, choroidal and retinal blood flow.

[Changes in intraocular pressure during pregnancy]. / Zmiany cisnienia wewnatrzgalkowego w przebiegu ciazy.

PURPOSE: The purpose of this study was to define physiological changes in intraocular pressure during pregnancy. MATERIAL AND METHODS: 182 healthy pregnant women were examined cross-sectionally throughout the pregnancy. After measuring systolic and diastolic blood pressure full ophthalmological examination was performed (visual acuity, refractive error, intraocular pressure, slit lamp examination and fundus exam). All subjects were free from any systemic or ocular diseases. RESULTS: Intraocular pressure significantly decreased during successive stages of pregnancy. The results are presented as means SD. In the control group mean IOP was 15.6 +/- 1.81 mmHg. During first ten weeks of pregnancy mean IOP was 15.33 +/- 1.98 mmHg, between 11-20 hbd was 14.52 +/- 2.37 mmHg, between 21-30 hbd was 13.47 +/- 2.19 mmHg, and towards the end of pregnancy (31-40 hbd) was 12.5 +/- 1.96 mmHg. The mean fall of IOP during whole pregnancy was 3.1 +/- 0.38 mmHg (p < 0.001). In these subjects pregnancy decreased IOP by 19.8%. CONCLUSIONS: The study results showed a gradual, statistically significant fall of intraocular pressure during pregnancy.

[Surgery in severe forms of allergic eye diseases]. / Postepowanie chirurgiczne w ciezkich postaciach alergii oczu.

Surgical treatment is performed in allergic eye diseases when drug treatment fails and the disease leads to conjunctival, corneal or palpebral disorders. Surgery procedures can be divided into early (surgery on palpebral conjunctiva, surgery on cornea) and late ones (decreasing tears outflow, plastic surgery on eyelids, cul de sac).