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1.
PLoS One ; 9(7): e101353, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25007052

RESUMEN

An abdominal aortic aneurysm is a pathological dilation of the abdominal aorta, which carries a high mortality rate if ruptured. The most commonly used surrogate marker of rupture risk is the maximal transverse diameter of the aneurysm. More recent studies suggest that wall stress from models of patient-specific aneurysm geometries extracted, for instance, from computed tomography images may be a more accurate predictor of rupture risk and an important factor in AAA size progression. However, quantification of wall stress is typically computationally intensive and time-consuming, mainly due to the nonlinear mechanical behavior of the abdominal aortic aneurysm walls. These difficulties have limited the potential of computational models in clinical practice. To facilitate computation of wall stresses, we propose to use a linear approach that ensures equilibrium of wall stresses in the aneurysms. This proposed linear model approach is easy to implement and eliminates the burden of nonlinear computations. To assess the accuracy of our proposed approach to compute wall stresses, results from idealized and patient-specific model simulations were compared to those obtained using conventional approaches and to those of a hypothetical, reference abdominal aortic aneurysm model. For the reference model, wall mechanical properties and the initial unloaded and unstressed configuration were assumed to be known, and the resulting wall stresses were used as reference for comparison. Our proposed linear approach accurately approximates wall stresses for varying model geometries and wall material properties. Our findings suggest that the proposed linear approach could be used as an effective, efficient, easy-to-use clinical tool to estimate patient-specific wall stresses.


Asunto(s)
Aorta Abdominal/patología , Aneurisma de la Aorta Abdominal/diagnóstico , Algoritmos , Aorta Abdominal/fisiopatología , Aneurisma de la Aorta Abdominal/fisiopatología , Humanos , Modelos Lineales , Modelos Biológicos , Músculo Liso Vascular/patología , Músculo Liso Vascular/fisiopatología , Mejoramiento de la Calidad , Riesgo , Medición de Riesgo , Índice de Severidad de la Enfermedad , Estrés Fisiológico
2.
J Vasc Surg ; 59(5): 1440-55, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24655750

RESUMEN

OBJECTIVE: The aim of this systematic review is to describe the literature and assessment tools evaluating vascular surgical operative performance that could potentially be used for the assessment of educational outcomes applicable to the Milestone Project and the Next Accreditation System. METHODS: A systematic review of PubMed/MEDLINE, EMBASE, PsycINFO, and key journals from 1985 to 2013 was performed to identify English-language articles describing assessment of vascular surgical skills and competence. Qualifying studies were abstracted for data concerning study aims, study and assessment setting, skills measured, and metrics used to determine competency. Strengths, weaknesses, and psychometric robustness of the assessment tools were determined. RESULTS: The literature search identified 617 citations. After title and abstract review, 65 articles were retrieved for full-text assessment and 48 articles were included in the final review. Twenty-nine articles assessed open vascular skills; 19, endovascular skills; six, nontechnical skills; and one, teamwork skills. The majority (84%) of studies were performed in a simulated environment, four (8%) were performed in the operating room, and the remaining three were performed in both a simulated environment and an operating room. Strengths and weaknesses of assessment tools were study and assessor dependent, with none applicable to all study scenarios or procedures. CONCLUSIONS: The literature describing assessment tools pertinent to vascular surgery is diverse. Existing assessment tools may be relevant to individual technical skill acquisition assessment; however, an operative assessment tool relevant to vascular/endovascular surgery and generalizable to the wide spectrum of technical and nontechnical skills pertinent to vascular surgery needs to be developed, validated, and implemented to allow the practical assessment of resident readiness to operate in an unsupervised setting.


Asunto(s)
Competencia Clínica , Educación de Postgrado en Medicina/métodos , Curva de Aprendizaje , Destreza Motora , Enseñanza/métodos , Procedimientos Quirúrgicos Vasculares/educación , Certificación , Curriculum , Evaluación Educacional , Humanos , Análisis y Desempeño de Tareas
3.
J Vasc Surg ; 59(2): 427-34, 2014 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-24103407

RESUMEN

OBJECTIVE: This study determined wound complication rates, intervention rates, failure mechanisms, patency, limb salvage, and overall survival after lower extremity revascularization using open vein harvest (OVH) vs endoscopic vein harvest (EVH) for critical limb ischemia. METHODS: A single-institution review was conducted of consecutive patients who underwent infrainguinal bypass with a single-segment reversed great saphenous vein between 2005 and 2012. RESULTS: A total of 251 patients with critical limb ischemia underwent revascularization, comprising 153 with OVH and 98 with EVH. The OVH group had a lower mean body mass index (26.7 vs 29.9 kg/m(2); P = .001). There were no other differences in demographics, comorbidities, medications, smoking, or in the proximal or distal anastomotic site. Median operative times were 249 minutes (OVH) vs 316 minutes (EVH; P < .001). Median postoperative hospital length of stay was 7 days (OVH) vs 5 days (EVH; P < .001). Median follow-up was 295 days (OVH) vs 313 days (EVH; P = .416). During follow-up, 21 OVH grafts (14%) and 27 EVH grafts (28%) underwent an intervention (P = .048). There were a similar number of surgical interventions: 50% (OVH) vs 61% (EVH; P = .449). Failed grafts had a mean of 1.2 stenoses per graft, regardless of harvest method. Median stenosis length was 2.1 cm (OVH) vs 2.5 cm (EVH; P = .402). At 1 and 3 years, the primary patency was 71% and 52% (OVH) vs 58% and 41% (EVH; P = .010), and secondary patency was 88% and 71% (OVH) vs 88% and 64% (EVH; P = .266). A secondary patency Cox proportional hazard model showed EVH had a hazard ratio of 2.93 (95% confidence interval, 1.03-8.33; P = .044). Overall and harvest-related wound complications were 44% and 29% (OVH) vs 37% and 12% (EVH; P = .226 and P = .002). At 5 years, amputation-free survival was 48% (OVH) vs 54% (EVH; P = .305), and limb salvage was 89% (OVH) and 91% (EVH; P = .615). CONCLUSIONS: OVH and EVH have similar failure mechanisms, limb salvage, amputation-free survival, and overall survival. EVH is associated with impaired patency, increased need for intervention, longer operative times, shorter hospital stays, and decreased vein harvest site wound complications. OVH of the great saphenous vein may provide optimal patency but was not necessarily associated with better patient-centered outcomes. Similar limb salvage rates and amputation-free survival may justify the use of EVH, despite inferior patency, to capture shorter hospital stays and decreased wound complications.


Asunto(s)
Endoscopía , Isquemia/cirugía , Extremidad Inferior/irrigación sanguínea , Vena Safena/trasplante , Recolección de Tejidos y Órganos/métodos , Injerto Vascular , Anciano , Anciano de 80 o más Años , Amputación Quirúrgica , Distribución de Chi-Cuadrado , Enfermedad Crítica , Supervivencia sin Enfermedad , Endoscopía/efectos adversos , Endoscopía/mortalidad , Femenino , Humanos , Isquemia/diagnóstico , Isquemia/mortalidad , Isquemia/fisiopatología , Estimación de Kaplan-Meier , Tiempo de Internación , Recuperación del Miembro , Masculino , Persona de Mediana Edad , Oregon , Modelos de Riesgos Proporcionales , Reoperación , Estudios Retrospectivos , Factores de Riesgo , Factores de Tiempo , Recolección de Tejidos y Órganos/efectos adversos , Recolección de Tejidos y Órganos/mortalidad , Resultado del Tratamiento , Injerto Vascular/efectos adversos , Injerto Vascular/mortalidad , Grado de Desobstrucción Vascular , Cicatrización de Heridas
4.
J Vasc Surg ; 58(4): 1076-9, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23465174

RESUMEN

Rotational vertebral artery occlusion, or bow hunter's stroke, is reversible, positional symptomatic vertebrobasilar ischemia. The typical mechanism of action is obstruction of a dominant vertebral artery with contralateral head rotation in the setting of baseline ipsilateral vertebral artery stenosis or occlusion. Here we present a rare case of mechanical occlusion of bilateral patent vertebral arteries manifesting as near syncope with rightward head rotation. Diagnostic cerebral angiography showed dynamic right C5 vertebral occlusion and left C2 vertebral occlusion. The patient underwent right C4/5 transverse process decompression. Postoperative angiogram showed patent flow through the right vertebral artery in neutral position and with head turn with resultant resolution of symptoms.


Asunto(s)
Movimientos de la Cabeza , Insuficiencia Vertebrobasilar/etiología , Angiografía Cerebral , Vértebras Cervicales/cirugía , Descompresión Quirúrgica/métodos , Humanos , Masculino , Persona de Mediana Edad , Rotación , Síncope/etiología , Resultado del Tratamiento , Ultrasonografía Doppler en Color , Insuficiencia Vertebrobasilar/diagnóstico , Insuficiencia Vertebrobasilar/cirugía
5.
Ann Vasc Surg ; 26(6): 871-80, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22284771

RESUMEN

Buerger's disease (thromboangiitis obliterans) is a nonatherosclerotic segmental inflammatory disease of small- and medium-sized arteries of the distal extremities of predominantly young male tobacco users. Early symptoms may include episodic pain and coldness in fingers, and late findings may present as intermittent claudication, skin ulcers, or gangrene requiring eventual amputation. Tobacco cessation is the cornerstone of treatment. Other modalities of reducing pain or avoiding amputation have not been as successful. This review summarizes in tabular form the types of treatment that have been used, including therapeutic angiogenesis.


Asunto(s)
Implantación de Prótesis Vascular , Fármacos Cardiovasculares/uso terapéutico , Procedimientos Endovasculares , Cese del Hábito de Fumar , Tromboangitis Obliterante/terapia , Adulto , Amputación Quirúrgica , Inductores de la Angiogénesis/uso terapéutico , Femenino , Humanos , Recuperación del Miembro , Masculino , Persona de Mediana Edad , Neovascularización Fisiológica/efectos de los fármacos , Medición de Riesgo , Factores de Riesgo , Tromboangitis Obliterante/diagnóstico , Tromboangitis Obliterante/epidemiología , Tromboangitis Obliterante/fisiopatología , Factores de Tiempo , Resultado del Tratamiento , Grado de Desobstrucción Vascular/efectos de los fármacos
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