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1.
Rev Med Chir Soc Med Nat Iasi ; 97(1): 405-10, 1993.
Article Ro | MEDLINE | ID: mdl-8153462

In a statistics including 954 patients with hyperthyroidism [correction of Huprotoncoses] treated between 1966-1989, the authors found 522 cases (54) with various associated cardiac disorders. Of these cases, 199 presented rhythm disturbances: extrasystolic arrhythmia, auricular fibrillation and flutter to which 34 postoperative arrhythmias are added. Cardiac insufficiency present in 46 cases was the main complication and end point of the various myocardial conditions. Ischemic cardiopathy (181 cases), arterial hypertension (98 cases) and rheumatic valvulopathies (9 cases), either isolated or dominating the clinical picture, complete the nosological spectrum of these disturbances. The frequency of associated conditions and the absence of some specific morphologic lesions suggest that thyrotoxicosis is rather an aggravating factor although in many cases the presence of a previous cardiac disease is excluded. The two objectives in the management of thyrocardiac diseases are the amelioration of cardiac condition and an endocrine balance. In the conditions of a careful selection and preoperative preparation, surgery gave good results consisting, in this series, in over 70% cures and ameliorations.


Heart Diseases/etiology , Hyperthyroidism/complications , Adult , Aged , Female , Graves Disease/complications , Graves Disease/diagnosis , Graves Disease/surgery , Heart Diseases/diagnosis , Heart Diseases/surgery , Humans , Hyperthyroidism/diagnosis , Hyperthyroidism/surgery , Male , Middle Aged , Remission Induction
13.
Rev Med Chir Soc Med Nat Iasi ; 86(1): 51-4, 1982.
Article Ro | MEDLINE | ID: mdl-25591249

48 patients with the diagnosis of ACH, admitted in the interval 1972-1981 and subjuected to corticotherapy were investigated by hepatic puncture biopsy with Vim-Silverman needls. The dose of prednison was of 15-20 mg daily for 2-4 years, with a mean 20 months. Corticotherapy was efficient in 73% of the cases, stabilization of the clinical and hepatic functional pictures being obtained. In 17% of the cases the hepatic process persited unmodified and in 10% ACH evolved towards cirrhosis.


Glucocorticoids/therapeutic use , Hepatitis B, Chronic/drug therapy , Hepatitis B, Chronic/pathology , Prednisone/therapeutic use , Biomarkers/blood , Biopsy , Disease Progression , Dose-Response Relationship, Drug , Glucocorticoids/administration & dosage , Hepatitis B, Chronic/blood , Humans , Prednisone/administration & dosage , Retrospective Studies , Treatment Outcome , gamma-Globulins/metabolism
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