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Emerg Infect Dis ; 25(9): 1625-1631, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-31441425

RESUMEN

Microsporidiosis is a fungal infection that generally causes digestive disorders, especially in immunocompromised hosts. Over a 4-day period in January 2018, 3 patients with hematologic malignancies who were admitted to the hematology unit of a hospital in France received diagnoses of Enterocytozoon bieneusi microsporidiosis. This unusually high incidence was investigated by sequence analysis at the internal transcribed spacer rDNA locus and then by 3 microsatellites and 1 minisatellite for multilocus genotyping. The 3 isolates had many sequence similarities and belonged to a new genotype closely related to genotype C. In addition, multilocus genotyping showed high genetic distances with all the other strains collected from epidemiologically unrelated persons; none of these strains belonged to the new genotype. These data confirm the epidemiologic link among the 3 patients and support a common source of infection.


Asunto(s)
Enterocytozoon/aislamiento & purificación , Neoplasias Hematológicas , Microsporidiosis/microbiología , Infección Hospitalaria/prevención & control , Enterocytozoon/genética , Heces/microbiología , Francia , Genotipo , Hematología , Hospitales Universitarios , Humanos
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