AiCarePWP: Deep learning-based novel research for Freezing of Gait forecasting in Parkinson.

BACKGROUND AND OBJECTIVES: Episodes of Freezing of Gait (FoG) are among the most debilitating motor symptoms of Parkinson's Disease (PD), leading to falls and significantly impacting patients' quality of life. Accurate assessment of FoG by neurologists provides crucial insights into patients' conditions and disease symptoms. This proposed strategy involves utilizing a Weighted Fuzzy Logic Controller, Kalman Filter, and Kaiser-Meyer-Olkin test to detect the gait parameters while walking, resting, and standing phases. Parameters such as neuromodulation format, intensity, duration, frequency, and velocity are computed to pre-empt freezing episodes, thus aiding their prevention. METHOD: The AiCarePWP is a wearable electronics device designed to identify instances when a patient is on the brink of experiencing a freezing episode and subsequently deliver a brief electrical impulse to the patient's shank muscles to stimulate movement. The AiCarePWP wearable device aims to identify impending freezing episodes in PD patients and deliver brief electrical impulses to stimulate movement. The study validates this innovative approach using plantar insoles with a 3D accelerometer and electrical stimulator, analysing data from the inertial measuring unit and plantar-pressure foot data to detect and predict FoG. RESULTS: Using a Convolutional Neural Network-based model, the study evaluated 47 gait features for their ability to differentiate resting, standing, and walking conditions. Variable selection was based on sensitivity, specificity, and overall accuracy, followed by Principal Component Analysis and Varimax rotation to extract and interpret factors. Factors with eigenvalues exceeding 1.0 were retained, and 37 features were retained. CONCLUSION: This study validates CNN's effectiveness in detecting FoG during various activities. It introduces a novel cueing method using electrical stimulation, which improves gait function and reduces FoG incidence in PD patients. Trustworthy wearable devices, based on Artificial Intelligence of Things (AIoT) and Artificial Intelligence of Medical Things (AIoMT), have been developed to support such interventions.

Synergistic Analysis of Lung Cancer's Impact on Cardiovascular Disease Using ML-Based Techniques.

Cancer patients are known to have a higher likelihood of developing Cardiovascular Disease (CVD) compared to non-cancer individuals. Although various types of cancer can contribute to the onset of CVD, lung cancer is inherently linked with increased susceptibility. To bridge this hypothesis, we propose a Lung cancer detection and Cardiovascular Disease Prediction (LCDP) system through lung Computed Tomography (CT) scan images. The lung cancer detection module of the LCDP system utilizes Transfer Learning (TL) with AdaDenseNet for classification. It employs the improvised Proximity-based Synthetic Minority Over-sampling Technique (Prox-SMOTE), improving accuracy. In the CVD prediction module, the feature extraction was performed using the VGG-16 model, followed by classification using a Support Vector Machine (SVM) classifier. The impact and interdependence of lung cancer on CVD were evident in our evaluation, with high accuracies of 98.28% for lung cancer detection and 91.62% for CVD prediction.

Multimodal-Boost: Multimodal Medical Image Super-Resolution Using Multi-Attention Network With Wavelet Transform.

Multimodal medical images are widely used by clinicians and physicians to analyze and retrieve complementary information from high-resolution images in a non-invasive manner. Loss of corresponding image resolution adversely affects the overall performance of medical image interpretation. Deep learning-based single image super resolution (SISR) algorithms have revolutionized the overall diagnosis framework by continually improving the architectural components and training strategies associated with convolutional neural networks (CNN) on low-resolution images. However, existing work lacks in two ways: i) the SR output produced exhibits poor texture details, and often produce blurred edges, ii) most of the models have been developed for a single modality, hence, require modification to adapt to a new one. This work addresses (i) by proposing generative adversarial network (GAN) with deep multi-attention modules to learn high-frequency information from low-frequency data. Existing approaches based on the GAN have yielded good SR results; however, the texture details of their SR output have been experimentally confirmed to be deficient for medical images particularly. The integration of wavelet transform (WT) and GANs in our proposed SR model addresses the aforementioned limitation concerning textons. While the WT divides the LR image into multiple frequency bands, the transferred GAN uses multi-attention and upsample blocks to predict high-frequency components. Additionally, we present a learning method for training domain-specific classifiers as perceptual loss functions. Using a combination of multi-attention GAN loss and a perceptual loss function results in an efficient and reliable performance. Applying the same model for medical images from diverse modalities is challenging, our work addresses (ii) by training and performing on several modalities via transfer learning. Using two medical datasets, we validate our proposed SR network against existing state-of-the-art approaches and achieve promising results in terms of structural similarity index (SSIM) and peak signal-to-noise ratio (PSNR).

I-Health: SDN-Based Fog Architecture for IIoT Applications in Healthcare.

The Industrial Internet of Things (IIoT) has been introduced in an era of increasingly broad potentials in the medical industry. In recent years, IIoT-based healthcare applications have grown in popularity, with the majority of them relying on Wireless Body Area Network (WBAN) for flexibility. There have been a few recent works that have investigated SDN-based fog architecture for constructing smart healthcare systems. However, the best fog node from the fog layer must be identified and limit the transmission of unnecessary data. To address this issue, the Intelligent Software-defined Fog Architecture (i-Health) is developed in this work. Based on the prior data pattern of each patient, the controller will decide whether to send the data to the fog layer. Furthermore, we introduced the Fog Ranking Service (FRS) and Fog Probing Service (FPS) to select the best fog node. The performance comparison reveals that the proposed i-Health outperforms existing benchmark approaches.

Harris Hawk Optimization: A Survey onVariants and Applications.

In this review, we intend to present a complete literature survey on the conception and variants of the recent successful optimization algorithm, Harris Hawk optimizer (HHO), along with an updated set of applications in well-established works. For this purpose, we first present an overview of HHO, including its logic of equations and mathematical model. Next, we focus on reviewing different variants of HHO from the available well-established literature. To provide readers a deep vision and foster the application of the HHO, we review the state-of-the-art improvements of HHO, focusing mainly on fuzzy HHO and a new intuitionistic fuzzy HHO algorithm. We also review the applications of HHO in enhancing machine learning operations and in tackling engineering optimization problems. This survey can cover different aspects of HHO and its future applications to provide a basis for future research in the development of swarm intelligence paths and the use of HHO for real-world problems.

CP-BDHCA: Blockchain-Based Confidentiality-Privacy Preserving Big Data Scheme for Healthcare Clouds and Applications.

Healthcare big data (HBD) allows medical stakeholders to analyze, access, retrieve personal and electronic health records (EHR) of patients. Mostly, the records are stored on healthcare cloud and application (HCA) servers, and thus, are subjected to end-user latency, extensive computations, single-point failures, and security and privacy risks. A joint solution is required to address the issues of responsive analytics, coupled with high data ingestion in HBD and secure EHR access. Motivated from the research gaps, the paper proposes a scheme, that integrates blockchain (BC)-based confidentiality-privacy (CP) preserving scheme, CP-BDHCA, that operates in two phases. In the first phase, elliptic curve cryptographic (ECC)-based digital signature framework, HCA-ECC is proposed to establish a session key for secure communication among different healthcare entities. Then, in the second phase, a two-step authentication framework is proposed that integrates Rivest-Shamir-Adleman (RSA) and advanced encryption standard (AES), named as HCA-RSAE that safeguards the ecosystem against possible attack vectors. CP-BDAHCA is compared against existing HCA cloud applications in terms of parameters like response time, average delay, transaction and signing costs, signing and verifying of mined blocks, and resistance to DoS and DDoS attacks. We consider 10 BC nodes and create a real-world customized dataset to be used with SEER dataset. The dataset has 30,000 patient profiles, with 1000 clinical accounts. Based on the combined dataset the proposed scheme outperforms traditional schemes like AI4SAFE, TEE, Secret, and IIoTEED, with a lower response time. For example, the scheme has a very less response time of 300 ms in DDoS. The average signing cost of mined BC transactions is 3,34 seconds, and for 205 transactions, has a signing delay of 1405 ms, with improved accuracy of ≈ 12% than conventional state-of-the-art approaches.

A simulated measurement for COVID-19 pandemic using the effective reproductive number on an empirical portion of population: epidemiological models.

COVID-19 as a global pandemic has had an unprecedented impact on the entire world. Projecting the future spread of the virus in relation to its characteristics for a specific suite of countries against a temporal trend can provide public health guidance to governments and organizations. Therefore, this paper presented an epidemiological comparison of the traditional SEIR model with an extended and modified version of the same model by splitting the infected compartment into asymptomatic mild and symptomatic severe. We then exposed our derived layered model into two distinct case studies with variations in mitigation strategies and non-pharmaceutical interventions (NPIs) as a matter of benchmarking and comparison. We focused on exploring the United Arab Emirates (a small yet urban centre (where clear sequential stages NPIs were implemented). Further, we concentrated on extending the models by utilizing the effective reproductive number (R t) estimated against time, a more realistic than the static R 0, to assess the potential impact of NPIs within each case study. Compared to the traditional SEIR model, the results supported the modified model as being more sensitive in terms of peaks of simulated cases and flattening determinations.

VIRFIM: an AI and Internet of Medical Things-driven framework for healthcare using smart sensors.

After affecting the world in unexpected ways, the virus has started mutating which is evident with the insurgence of its new variants. The governments, hospitals, schools, industries, and humans, in general, are looking for a potential solution in the vaccine which will eventually be available, but its timeline for eradicating the virus is yet unknown. Several researchers have encouraged and recommended the use of good practices such as physical healthcare monitoring, immunity boosting, personal hygiene, mental healthcare, and contact tracing for slowing down the spread of the virus. In this article, we propose the use of smart sensors integrated with the Internet of Medical Things to cover the spectrum of good practices in an automated manner. We present hypothetical frameworks for each of the good practice modules and propose the VIrus Resistance Framework using the Internet of Medical Things (VIRFIM) to tie all the individual modules in a unified architecture. Furthermore, we validate the realization of VIRFIM framework with two case studies related to physical activity monitoring and stress detection services. We envision that VIRFIM would be influential in assisting people with the new normal for current and future pandemics as well as instrumental in halting the economic losses, respectively. We also provide potential challenges and their probable solutions in compliance with the proposed VIRFIM.

Triage of potential COVID-19 patients from chest X-ray images using hierarchical convolutional networks.

The current COVID-19 pandemic has motivated the researchers to use artificial intelligence techniques for a potential alternative to reverse transcription-polymerase chain reaction due to the limited scale of testing. The chest X-ray (CXR) is one of the alternatives to achieve fast diagnosis, but the unavailability of large-scale annotated data makes the clinical implementation of machine learning-based COVID detection difficult. Another issue is the usage of ImageNet pre-trained networks which does not extract reliable feature representations from medical images. In this paper, we propose the use of hierarchical convolutional network (HCN) architecture to naturally augment the data along with diversified features. The HCN uses the first convolution layer from COVIDNet followed by the convolutional layers from well-known pre-trained networks to extract the features. The use of the convolution layer from COVIDNet ensures the extraction of representations relevant to the CXR modality. We also propose the use of ECOC for encoding multiclass problems to binary classification for improving the recognition performance. Experimental results show that HCN architecture is capable of achieving better results in comparison with the existing studies. The proposed method can accurately triage potential COVID-19 patients through CXR images for sharing the testing load and increasing the testing capacity.

Detecting COVID-19-Related Fake News Using Feature Extraction.

Since its emergence in December 2019, there have been numerous posts and news regarding the COVID-19 pandemic in social media, traditional print, and electronic media. These sources have information from both trusted and non-trusted medical sources. Furthermore, the news from these media are spread rapidly. Spreading a piece of deceptive information may lead to anxiety, unwanted exposure to medical remedies, tricks for digital marketing, and may lead to deadly factors. Therefore, a model for detecting fake news from the news pool is essential. In this work, the dataset which is a fusion of news related to COVID-19 that has been sourced from data from several social media and news sources is used for classification. In the first step, preprocessing is performed on the dataset to remove unwanted text, then tokenization is carried out to extract the tokens from the raw text data collected from various sources. Later, feature selection is performed to avoid the computational overhead incurred in processing all the features in the dataset. The linguistic and sentiment features are extracted for further processing. Finally, several state-of-the-art machine learning algorithms are trained to classify the COVID-19-related dataset. These algorithms are then evaluated using various metrics. The results show that the random forest classifier outperforms the other classifiers with an accuracy of 88.50%.