1.
J Org Chem
; 89(4): 2759-2763, 2024 Feb 16.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38308650
RESUMEN
On the basis of steric hindrance, one carbonyl group in a diketone can be reduced in a regioselective manner, with high enantioselectivity. The methodology can be extended to ketones with varied length of hydrocarbon chain spacing, and the products can be converted by oxidation to hydroxy esters or lactones without loss of enantiopurity.