[Mechanism of self-maintenance of experimental atherogenic hyperlipoproteinemia]. / O mekhanizme samopodderzhaniia éksperimental'noi aterogennoi giperlipoproteinemii.

Disorders of lipid catabolism in the liver and increased formation and intensified secretion into the blood of lipoproteins synthesized in the liver evidently play a significant role in the maintenance of experimental atherogenic hyperlipoproteinemia induced in rabbits by prolonged administration of atherogenic lipoproteins.

[The erythrocyte functional status and phospholipid composition in breast cancer patients]. / Funktsional'noe sostoianie i fosfolipidnyi sostav éritrotsitov u bol'nykh rakom molochnoi zhelezy.

A study of the osmotic resistance of both red blood cells and phospholipids of whole blood and isolated red blood cells showed breast cancer with symptoms of metastasis to involve perverted influence of calcium ions on osmoerythrograms. It is also characterized by similarly high levels of lysophospholipids both in whole blood and in isolated red blood cells and phosphatidylinositol levels which are lower than in metastasis-free cases. Red blood cells from cases of metastatic spreading revealed relatively lower values of the phosphatidylcholine/phosphatidylethanolamine ratio, too.

[The phosphatidylinositol content of the blood in cancer patients]. / Soderzhanie fosfatidilinozitov v krovi onkologicheskikh bol'nykh.

Phosphatidyl inosite level was measured in the whole blood, plasma, erythrocytes and platelets of patients with cancer of various sites (270), benign tumors (50), and hemoblastoses and anemia (60 cases). Phosphatidyl inosite levels in all the substrates in cancer patients, on the average, proved half the normal one while, in the benign tumor group, they only tended to decrease. The levels did not depend upon blood count.

[Teaching medical radiology to foreign students]. / Prepodovanie meditsinskoi radiologii inostrannym studentam.

The paper is concerned with activities aimed at improvement of teaching medical radiology to foreign students. To overcome language difficulties and differences in the national secondary school educational systems, summary lectures with schemes are proposed enabling foreign students to rapidly orientate in the studied material during their independent work. Reference materials for foreign students contribute to the motivation of foreign students' cognition and drawing the teaching process near conditions of the students' future working activities.

[Lipid composition, activity and isoenzyme spectrum of certain lymphoid cell enzymes and the effect of hydrocortisone on them]. / Lipidnyi sostav, aktivnost' i izofermentnyi spektr nekotorykh fermentov limfoidnykh kletok i vliianie na nikh gidrokortizona.

Activities of glucose-6-phosphate dehydrogenase (G6PD), lactate dehydrogenase (LDH) as well as lipolytic activity were decreased in lymphoid cells of lymphatic glands from rabbit mesentery as compared with corresponding levels of the enzymatic activity in cells of bone marrow. The isozyme spectra of G6PD, LDH and unspecific esterases were dissimilar in lymphoid and bone marrow cells. Content of total lipids, triglycerides, free fatty acids as well as the hexokinase and lipolytic activities were decreased in the cells after treatment with hydrocortisone.

[Importance of the occupational factor in the realization of influences that induce atherogenic disorders of lipid metabolism]. / Znachenie professional'nogo faktora v realizatsii nekotorykh vliianii, vyzyvaiushchikh aterogennye rasstroistva lipidnogo obmena.

The phenotype was determined and the concentration of the main classes of lipids was studied in blood serum of 248 engineers and other technical workers (ETW). High prevalence of hyperproteinemia, type IV in particular, was revealed among the administrative group fo ETW whose work is associated with marked neuro-emotional stress and high personal responsibility. This occupational factor promoted and levelled the age shifts in lipid metabolism and contributed to the realization of the hereditary determined disorders of lipid metabolism.

[Isoenzyme spectrum and activity of several enzymes of bone marrow erythroid and myeloid cells in rabbits and changes in them under the influence of hydrocortisone]. / Izofermentnyi spektr i aktivnost' nekotorykh fermentov éritroidnykh i mieloidnykh kletok kostnogo mozga krolika i osobennosti ikh izmenenii pod vliianiem gidrokortizona.

Rabbit myeloid myelocaryocytes possessed higher activities of hexokinase (HK) and lactate dehydrogenase (LDH) as compared with those of erythroid cells. The lypolytic activity was twice as high in myeloid myelocaryocytes as in erythroid ones. Both strains of medullar cells did not differ in the activity of glucose-6-phosphate dehydrogenase (G6PD). But the isoenzyme spectra of G6PD varied distinctly in these cells; HK and LDH isoenzyme spectra were the same both in myeloid and erythroid cells. The enzymatic activity was altered dissimilarly in myeloid and erythroid cells after administration of hydrocortisone. In myeloid cells the HK activity was decreased, in the erythroid cells--the HK activity tended to increase and the lipolytic activity was decreased. Alterations in the isoenzyme spectra of G6PD and LDH, caused by hydrocortisone administration, exhibited similar patterns in myeloid and erythroid cells.

[Morphological and biochemical changes in the myocardium after sudden death from ischemic heart disease]. / Morfologicheskie i biokhimicheskie izmeneniia miokarda pri vnezapnoi smerti ot ishemicheskoi bolezni serdtsa.

The myocardium was examined in 44 persons who had suddenly died of ischemic heart disease, in 37 who had died of injury, and in 28 who had died of alcohol poisoning. Those with ischemic heart disease had foci of necrosis of the muscle fibers, severe disturbances in microcirculation, changes in the activity of certain myocardial enzymes and in the content of lipids in the myocardium. Biochemical changes similar to these in many respects were revealed in individuals who had died of alcohol poisoning, in view of which alcohol poisoning may be a factor conducive to sudden death in ischemic heart disease.