[Changes of hemodynamics during the treatment of patients with neurologic pain syndromes by the method of dynamic electrical neurostimulation].

The Doppler ultrasound technique was used to study blood flow characteristics for the evaluation of the efficacy of the treatment of painful neurological syndromes with the help of a DiaDENS apparatus allowing for dynamic changes of electrostimulation parameters. A significant improvement of the extracranial cerebral blood flow was achieved as early as the mid-course of 10 treatment sessions when the most pronounced stabilization of the clinical characteristics was apparent. Marked heterogeneity of responses of extracranial vessels to the therapeutic effect of dynamic electrostimulation (DENS) was documented, possibly due to the redistribution of the blood flow in certain vascular areas during the treatment. DENS applied to the lumbar region was shown to induce positive dynamics of the initially impaired blood flow in the tibial artery. It is concluded that positive hemodynamic changes in the cerebral blood flow constitute an important component of the anesthetic and general sanogenetic actions of DENS.

[Clinico-pharmacologic aspects of the use of ofloxacin]. / Kliniko-farmakologicheskie aspekty primeneniia ofloksatsina.

Ofloxacin was used in the treatment of 124 patients with bronchopulmonary diseases, the diseases of the biliary system and other infectious inflammatory diseases of the internal organs. The microbiological and pharmacokinetic indices as well as the immune status were investigated. The drug proved to be efficient in the treatment of 78.9 per cent of the cases. The pharmacokinetic indices were evident of the fact that the treatment of severe cases should be started with the drug intravenous administration. Ofloxacin had no negative effects on the immune status.

[Role of electrolytes in the pathogenesis of arterial spasm and muscle cramps in varicose veins of the lower limbs]. / Rol' élektrolitov v patogeneze arterial'nogo spazma i myshechnyk sudorog pri varikoznoi bolezni nizhnikh konechnostei.

The blood magnesium and calcium content and the blood flow in the limbs was studied in 68 patients suffering from varicosity, 42 of whom had trophic ulcers of the legs. It was established that diminished content of magnesium in blood serum contributes to the development of hypercalcemia, spasm of arterioles, and the occurrence of muscular convulsions and trophic disorders and thus plays an essential role in the pathogenesis of changes of the blood flow and trophic disorders. Administration of magnesium preparations in the preoperative period improved circulation in the limb and relieved muscular convulsions completely.

[Possibility of predicting and preventing postoperative complications leading to relaparotomy]. / Vozmozhnosti prognozirovaniia i profilaktiki posleoperatsionnykh oslozhnenii, privodiashchikh k relaparotomii.

The occurrence of relaparotomies is known to be 1,2% of operations on the abdomen organs. Pyo-inflammatory complications are responsible for more than half cases resulting in relaparotomies. Relaparotomies are divided into emergent and urgent, radical and palliative. A system for prognosis of complications and differential diagnosis of postoperative paresis of the gastro-intestinal tract and postoperative peritonitis is presented. Prophylactics of postoperative complications reduced lethality after relaparotomies from 79% to 56%.