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Humans , Female , Middle Aged , Lichen Planus/diagnosis , Lichen Planus/pathology , Lichen Planus/therapy , Alopecia/diagnosis , Alopecia/pathology , Alopecia/therapy , Diagnosis, Differential , Scalp/injuries , Scalp/pathology , Scalp/physiopathology , Hair Diseases/complications , Hair Diseases/diagnosis , Hair Diseases/therapy
El carcinoma de cérvix es la segunda neoplasia más común en la mujer. Es infrecuente la afectación cutánea incluso en los estadios terminales de laenfermedad. Describimos una paciente con carcinoma de cérvix que desarrolló una metástasis cutánea inflamatoria (AU)
Carcinoma of the cervix is the second most common malignancy in women. Cutaneous involvement originating from cervical cancer is particularlyunusual, even in the terminal stage of the disease. A patient with cervical cancer who developed an inflammatory cutaneous metastases is reported (AU)
Humans , Female , Middle Aged , Uterine Cervical Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Skin Neoplasms/secondary , Tomography, X-Ray Computed
Introducción. La escrofulodermia se produce por la extensión directa a la piel de un foco tuberculoso subyacente a nivel óseo, articular o incluso del epidídimo, pero sucede con mayor frecuencia sobre un ganglio linfático, sobre todo los cervicales. Métodos. Analizamos todos los casos de escrofulodermia de origen óseo o articular vistos en el área sanitaria de Ferrol, población actual de 220.000 habitantes, en un periodo de 15 años. Describimos los datos clínicos, histopatológicos y microbiológicos de los pacientes. Resultados. Encontramos 6 casos de escrofulodermia con tuberculosis osteoarticular. Esta serie incluye 5 varones y una mujer, de entre 37 y 80 años de edad. Se encontró afectación de órganos internos en tres pacientes (50 %). Conclusión. La tuberculosis osteoarticular constituye el 10 % de todas las infecciones tuberculosas extrapulmonares. Hay una alta probabilidad de afectación interna en pacientes con escrofulodermia. Se debe descartar afectación ósea subyacente en todos los pacientes con escrofulodermia, sobre todo en los que muestran una respuesta incompleta al tratamiento médico
Introduction. Scrofuloderma results from direct extension of an underlying tuberculous focus such as bone, joint or even the epydidimus to the overlying skin, but is more frequent over a lymph node, mainly in the cervical region. Methods. We analysed all cases of scrofuloderma with a bone or joint focus evaluated in the sanitary area of Ferrol, with a current population of 220,000, during a 15-year period. We describe the clinical, histopathological, and microbiological data of patients. Results. We found 6 cases of scrofuloderma with osteoarticular tuberculosis. This series includes five men and one woman, aged 37 to 80. Visceral involvement was found in 3 patients (50 %). Conclusion. Osteoarticular tuberculosis comprises 10 % of all extrapulmonary tuberculous infections. There is a high probability of visceral involvement in patients with scrofuloderma. Underlying bone involvement should be rule out in all patients with scrofuloderma, especially in those with incomplete response to medical treatment
Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Humans , Tuberculosis, Cutaneous/complications , Tuberculosis, Osteoarticular/complications , Antitubercular Agents/administration & dosage , Tuberculosis, Cutaneous/diagnosis , Tuberculosis, Cutaneous/drug therapy , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Osteoarticular/drug therapy , Prospective Studies , Treatment Outcome
INTRODUCTION: Scrofuloderma results from direct extension of an underlying tuberculous focus such as bone, joint or even the epididymis to the overlying skin, but is more frequent over a lymph node, mainly in the cervical region. METHODS: We analysed all cases of scrofuloderma with a bone or joint focus evaluated in the sanitary area of Ferrol, with a current population of 220,000, during a 15-year period. We describe the clinical, histopathological, and microbiological data of patients. RESULTS: We found 6 cases of scrofuloderma with osteoarticular tuberculosis. This series includes five men and one woman, aged 37 to 80. Visceral involvement was found in 3 patients (50 %). CONCLUSION: Osteoarticular tuberculosis comprises 10 % of all extrapulmonary tuberculous infections. There is a high probability of visceral involvement in patients with scrofuloderma. Underlying bone involvement should be rule out in all patients with scrofuloderma, especially in those with incomplete response to medical treatment.
Tuberculosis, Cutaneous/epidemiology , Tuberculosis, Osteoarticular/epidemiology , Adult , Aged , Aged, 80 and over , Antitubercular Agents/therapeutic use , Combined Modality Therapy , Comorbidity , Female , Humans , Male , Middle Aged , Prospective Studies , Spain/epidemiology , Tuberculosis, Cutaneous/diagnosis , Tuberculosis, Cutaneous/drug therapy , Tuberculosis, Cutaneous/etiology , Tuberculosis, Cutaneous/surgery , Tuberculosis, Lymph Node/complications , Tuberculosis, Osteoarticular/complications , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Osteoarticular/drug therapy , Tuberculosis, Osteoarticular/surgery
There are several reports of porokeratosis in the context of immmunosuppressive diseases. These mainly include organ transplant, HIV infection, lymphomas and some inflammatory and autoimmune diseases commonly treated with immunosuppresive drugs or chemotherapy. Disseminated superficial actinic porokeratosis is the clinical variant of porokeratosis that most frequently develops in immunosuppressive states. We report a case of porokeratosis in a woman with dermatomyositis.
Dermatomyositis/complications , Porokeratosis/etiology , Aged , Dermatomyositis/drug therapy , Dermatomyositis/immunology , Dermatomyositis/pathology , Female , Humans , Immunocompromised Host , Immunosuppressive Agents/adverse effects , Immunosuppressive Agents/therapeutic use , Methotrexate/adverse effects , Methotrexate/therapeutic use , Porokeratosis/immunology , Porokeratosis/pathology , Prednisone/adverse effects , Prednisone/therapeutic use
Se han descrito varios casos de poroqueratosis en el curso de enfermedades con inmunosupresión. Éstas incluyen sobre todo trasplantes de órganos, infección por virus de la inmunodeficiencia humana (VIH), linfomas y varias enfermedades inflamatorias o autoinmunes normalmente tratadas con fármacos inmunosupresores o quimioterapia. La poroqueratosis actínica superficial diseminada es la variante clínica de poroqueratosis que con más frecuencia se desarrolla en estados de inmunosupresión. Describimos un caso de poroqueratosis en una paciente mujer con dermatomiositis
There are several reports of porokeratosis in the context of immmunosuppressive diseases. These mainly include organ transplant, HIV infection, lymphomas and some inflammatory and autoimmune diseases commonly treated with immunosuppresive drugs or chemotherapy. Disseminated superficial actinic porokeratosis is the clinical variant of porokeratosis that most frequently develops in immunosuppressive states. We report a case of porokeratosis in a woman with dermatomyositis
Female , Middle Aged , Humans , Porokeratosis/complications , Porokeratosis/diagnosis , Porokeratosis/therapy , Dermatomyositis/complications , Dermatomyositis/diagnosis , Dermatomyositis/therapy , Immunosuppression Therapy/methods , Intussusception/complications , Intussusception/diagnosis , Biopsy/methods , Hyperkeratosis, Epidermolytic/complications , Hyperkeratosis, Epidermolytic/diagnosis
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Male , Adult , Humans , Perianal Glands/physiopathology , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/diagnosis , Hyperkeratosis, Epidermolytic/complications , Hyperkeratosis, Epidermolytic/diagnosis , Folliculitis/complications , Folliculitis/diagnosis , Skin Ulcer/complications , Skin Ulcer/diagnosis , Perianal Glands/injuries , Perianal Glands/pathology , Fissure in Ano/complications , Nontuberculous Mycobacteria , Nontuberculous Mycobacteria/pathogenicity , Folliculitis/pathology , Folliculitis/physiopathology , Anal Canal/injuries , Anal Canal/pathology
No disponible
Male , Adolescent , Humans , Hair Diseases/diagnosis , Pilomatrixoma/diagnosis , Skin Neoplasms/diagnosis
