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2.
Rinsho Shinkeigaku ; 60(1): 32-36, 2020 Jan 30.
Article Ja | MEDLINE | ID: mdl-31852867

Epilepsy surgery for patients with drug-resistant epilepsy after anti-N-methyl-D-aspartate (NMDA) receptor encephalitis has been rarely reported. The present study reports two patients with anti-NMDA receptor encephalitis, who later underwent epilepsy surgery due to drug-resistant epilepsy. The patients had refractory status epilepticus in the acute phase. The cerebrospinal fluid was positive for anti-NMDA receptor antibodies. Systemic corticosteroid therapy and plasma exchange were effective. Seizure control, however, worsened over several months after discharge, and was refractory to antiepileptic drugs. They underwent palliative epilepsy surgery, and their seizure control improved. Epilepsy surgery should be considered in patients with drug-resistant epilepsy after anti-NMDA receptor encephalitis.


Encephalitis/complications , Epilepsy/surgery , Receptors, N-Methyl-D-Aspartate , Adult , Drug Resistance , Female , Humans , Male , Palliative Care , Treatment Outcome , Young Adult
3.
Brain Nerve ; 69(6): 665-669, 2017 Jun.
Article Ja | MEDLINE | ID: mdl-28596469

A 38-year-old woman developed disturbance of consciousness and quadriplegia. Magnetic resonance images showed scattered acute infarcts in both hemispheres and bilateral occlusion of the intracranial artery (ICA). Immediate mechanical thrombectomy restored the patency of the ICA. Contrast-enhanced computed tomography revealed bilateral wall thickening of the abdominal aorta and the iliac arteries. This finding and an elevated erythrocyte sedimentation rate supported the diagnosis of Takayasu arteritis. Here, we thus report a rare case of Takayasu arteritis with acute bilateral occlusion of the internal carotid arteries.


Carotid Artery, Internal/diagnostic imaging , Coronary Occlusion/diagnostic imaging , Takayasu Arteritis/diagnostic imaging , Acute Disease , Adult , Coronary Occlusion/drug therapy , Drug Combinations , Female , Humans , Magnetic Resonance Angiography , Multimodal Imaging , Tomography, X-Ray Computed
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