RESUMEN
Nevus sebaceus (NS)(organoid nevus) is a benign follicular neoplasm that commonly occurs on the scalp, face, or neck. With time, it may give rise to benign or malignant tumors such as trichoblastoma, syringocystadenoma papilliferum, and basal cell carcinoma (BCC). Rarely, other types of neoplasms may develop. We present a 76-year-old woman with several trichoblastomas as well as a primary cutaneous apocrine carcinoma arising within a preexisting NS that was treated with frozen section excision.
Asunto(s)
Adenocarcinoma/diagnóstico , Neoplasias de Cabeza y Cuello/diagnóstico , Neoplasias Primarias Múltiples/diagnóstico , Neoplasias de las Glándulas Sebáceas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Adenocarcinoma/patología , Adenocarcinoma/cirugía , Anciano , Diagnóstico Diferencial , Femenino , Neoplasias de Cabeza y Cuello/patología , Neoplasias de Cabeza y Cuello/cirugía , Humanos , Neoplasias Primarias Múltiples/patología , Neoplasias Primarias Múltiples/cirugía , Cuero Cabelludo , Enfermedades de las Glándulas Sebáceas , Neoplasias de las Glándulas Sebáceas/patología , Neoplasias de las Glándulas Sebáceas/cirugía , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/cirugíaRESUMEN
Imiquimod is a topical immunomodulating medication approved by the US Food and Drug Administration for the treatment of condyloma acuminata, actinic keratoses (AKs), and superficial basal cell carcinoma (BCC). Imiquimod commonly is used off label for its antiviral and antitumoral effects. We present a case of a 51-year-old man with vitiligolike depigmentation following treatment of periungual verruca vulgaris with imiquimod therapy.
Asunto(s)
Adyuvantes Inmunológicos/efectos adversos , Aminoquinolinas/efectos adversos , Hipopigmentación/inducido químicamente , Paroniquia/tratamiento farmacológico , Enfermedades Cutáneas Virales/tratamiento farmacológico , Verrugas/tratamiento farmacológico , Adyuvantes Inmunológicos/uso terapéutico , Aminoquinolinas/uso terapéutico , Humanos , Imiquimod , Masculino , Persona de Mediana EdadRESUMEN
Aphthous stomatitis is a painful and often recurrent inflammatory process of the oral mucosa that can appear secondary to various well-defined disease processes. Idiopathic recurrent aphthous stomatitis is referred to as recurrent aphthous stomatitis. The differential diagnosis for recurrent aphthous ulcerations is extensive and ranges from idiopathic benign causes to inherited fever syndromes, to connective tissue disease, or even inflammatory bowel diseases. A thorough history and review of systems can assist the clinician in determining whether it is related to a systemic inflammatory process or truly idiopathic. Management of aphthous stomatitis is challenging. For recurrent aphthous stomatitis or recalcitrant aphthous stomatitis from underlying disease, first-line treatment consists of topical medications with use of systemic medications as necessary. Herein, the authors discuss the differential diagnosis and treatment ladder of aphthous stomatitis as described in the literature.